Reactome | PDE6D dissociates from ARL13B:INPP5E

PDE6D dissociates from ARL13B:INPP5E

Stable Identifier

R-HSA-5638012

Type

Reaction [dissociation]

Species

Homo sapiens

Compartment

cilium

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ARL13B promotes the ciliary localization of INPP5E by interacting with it directly and displacing PDE6D from the complex (Humbert et al, 2012).

Literature References

PubMed ID	Title	Journal	Year
23150559	ARL13B, PDE6D, and CEP164 form a functional network for INPP5E ciliary targeting Humbert, MC, Weihbrecht, K, Searby, CC, Li, Y, Pope, RM, Sheffield, VC, Seo, S	Proc. Natl. Acad. Sci. U.S.A.	2012