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SIK1 [nucleoplasm]
Stable Identifier
R-HSA-5656504
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Serine/threonine-protein kinase SIK1 ecNumber2.7.11.1/ecNumber, SIK1_HUMAN
Locations in the PathwayBrowser
Expand all
Circadian Clock (Homo sapiens)
Expression of PERIOD-1 (Homo sapiens)
SIK1 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:P57059 SIK1
Gene Names
SIK1, SIK, SNF1LK
Chain
chain:1-783
Reference Genes
BioGPS Gene:102724428 SIK1
BioGPS Gene:150094 SIK1
COSMIC (genes):SIK1 SIK1
CTD Gene:150094 SIK1
dbSNP Gene:102724428 SIK1
dbSNP Gene:150094 SIK1
ENSEMBL:ENSG00000142178 SIK1
ENSEMBL_homo_sapiens_GENE:ENSG00000142178.9 SIK1
HGNC:11142 SIK1
KEGG Gene (Homo sapiens):102724428 SIK1
KEGG Gene (Homo sapiens):150094 SIK1
Monarch:102724428 SIK1
Monarch:150094 SIK1
NCBI Gene:102724428 SIK1
NCBI Gene:150094 SIK1
OMIM:605705 SIK1
UCSC:P57059 SIK1
Reference Transcript
RefSeq:NM_001320643.2 SIK1
RefSeq:NM_173354.4 SIK1
Other Identifiers
11716771_s_at
150094
16926200
208078_PM_s_at
208078_s_at
232470_3p_at
232470_PM_at
232470_at
33439_at
3934118
3934119
3934120
3934121
3934122
3934124
3934125
3934127
3934128
3934129
3934131
3934132
3934133
3934134
3934137
3934139
3934141
3934144
3934145
8070665
A_23_P132115
A_24_P237231
D15050_at
GE62158
GO:0000166
GO:0000278
GO:0000287
GO:0002028
GO:0003824
GO:0004672
GO:0004674
GO:0005515
GO:0005524
GO:0005634
GO:0005737
GO:0005975
GO:0006351
GO:0006355
GO:0006468
GO:0006629
GO:0007049
GO:0007346
GO:0008140
GO:0010830
GO:0010868
GO:0012501
GO:0016301
GO:0016310
GO:0016740
GO:0019901
GO:0023052
GO:0030154
GO:0032792
GO:0035556
GO:0036211
GO:0042826
GO:0043153
GO:0043226
GO:0043276
GO:0045595
GO:0045721
GO:0046777
GO:0046872
GO:0048511
GO:0048856
GO:0055007
GO:0071889
GO:0106310
GO:0140096
GO:2000210
HMNXSV003012193
Hs.283778.0.S1_3p_at
Hs.283778.0.S1_3p_x_at
ILMN_1717639
PH_hs_0018562
PH_hs_0033027
TC21000506.hg
g13540478_3p_s_at
This entity regulates
Negatively
Expression of PERIOD-1
(Homo sapiens)
Cross References
RefSeq
NP_775490.2
,
NP_001307572.1
ZINC - World Drugs
SIK1_HUMAN
Guide to Pharmacology - Targets
2197
OpenTargets
ENSG00000142178
ZINC - FDA approved
SIK1_HUMAN
ZINC - Substances
SIK1_HUMAN
ZINC target
P57059
ZINC - Biogenic
SIK1_HUMAN
PRO
P57059
ZINC - Investigational
SIK1_HUMAN
GeneCards
P57059
HPA
ENSG00000142178-SIK1
Ensembl
ENSG00000142178
,
ENST00000270162
,
ENSP00000270162
Pharos - Targets
P57059
Orphanet
23215
ZINC - Predictions - Purchasable
SIK1_HUMAN
HMDB Protein
HMDBP01197
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P63104 YWHAZ
2
YWHAZ [nucleoplasm]
(R-HSA-450469)
YWHAZ [cytosol]
(R-HSA-206099)
0.677
5
UniProt:P62258 YWHAE
1
YWHAE [cytosol]
(R-HSA-194368)
0.669
4
UniProt:Q9BRT9 GINS4
1
GINS4 [nucleoplasm]
(R-HSA-176963)
0.527
2
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