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Ub-SNCA [cytosol]
Stable Identifier
R-HSA-5660754
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Alpha-synuclein, SYUA_HUMAN, Monoubiquitinated SNCA
Locations in the PathwayBrowser for interactor UniProt:P68363 TUBA1B
Expand all
Metabolism of proteins (Homo sapiens)
Amyloid fiber formation (Homo sapiens)
USP9X binds Ub-SNCA (Homo sapiens)
Ub-SNCA [cytosol] (Homo sapiens)
Ub-SNCA dissociates from the conjugating enzyme (Homo sapiens)
Ub-SNCA [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P37840 SNCA
Gene Names
SNCA, NACP, PARK1
Chain
chain:1-140
Reference Genes
BioGPS Gene:6622 SNCA
COSMIC (genes):SNCA SNCA
CTD Gene:6622 SNCA
dbSNP Gene:6622 SNCA
ENSEMBL:ENSG00000145335 SNCA
HGNC:11138 SNCA
KEGG:hsa:6622 SNCA
Monarch:6622 SNCA
NCBI Gene:6622 SNCA
OMIM:163890 SNCA
UCSC:P37840 SNCA
Reference Transcript
RefSeq:NM_001146054.1 SNCA
RefSeq:XM_017008563.1 SNCA
RefSeq:NM_000345.3 SNCA
RefSeq:NM_007308.2 SNCA
RefSeq:XM_017008562.1 SNCA
RefSeq:NM_001146055.1 SNCA
RefSeq:XM_011532208.2 SNCA
Other Identifiers
11731446_s_at
11731447_x_at
11731448_a_at
11739782_a_at
11753730_a_at
11753731_x_at
11754090_a_at
16977986
204466_PM_s_at
204466_s_at
204467_PM_s_at
204467_s_at
207827_PM_x_at
207827_x_at
211546_PM_x_at
211546_x_at
236081_PM_at
236081_at
2777711
2777712
2777715
2777716
2777717
2777718
2777719
2777722
2777741
2777742
2777743
2777744
2777746
2777749
2777750
2777751
2777752
2777753
2777754
2777756
2777769
3468050
37291_r_at
44191_at
6622
8101762
A_23_P29939
A_32_P109653
GE57593
GO:0000122
GO:0000149
GO:0000287
GO:0000976
GO:0001774
GO:0001921
GO:0001956
GO:0001963
GO:0002376
GO:0003677
GO:0003779
GO:0003824
GO:0004860
GO:0005507
GO:0005509
GO:0005515
GO:0005543
GO:0005576
GO:0005615
GO:0005634
GO:0005737
GO:0005739
GO:0005764
GO:0005773
GO:0005829
GO:0005856
GO:0005886
GO:0005938
GO:0006091
GO:0006355
GO:0006469
GO:0006629
GO:0006631
GO:0006638
GO:0006644
GO:0006919
GO:0007005
GO:0007006
GO:0007268
GO:0007269
GO:0008092
GO:0008198
GO:0008270
GO:0008289
GO:0008344
GO:0009410
GO:0010040
GO:0010517
GO:0010642
GO:0012501
GO:0014048
GO:0014059
GO:0015629
GO:0016020
GO:0016079
GO:0016082
GO:0016192
GO:0016234
GO:0016491
GO:0019894
GO:0022898
GO:0023052
GO:0030424
GO:0030426
GO:0030544
GO:0030672
GO:0031092
GO:0031115
GO:0031623
GO:0031648
GO:0032026
GO:0032410
GO:0032496
GO:0032769
GO:0032991
GO:0033138
GO:0034330
GO:0034341
GO:0034599
GO:0035493
GO:0035543
GO:0040012
GO:0042393
GO:0042416
GO:0042417
GO:0042775
GO:0042802
GO:0042995
GO:0043014
GO:0043025
GO:0043027
GO:0043030
GO:0043065
GO:0043066
GO:0043154
GO:0043226
GO:0043524
GO:0043679
GO:0045202
GO:0045807
GO:0045920
GO:0045921
GO:0046872
GO:0046928
GO:0048156
GO:0048168
GO:0048169
GO:0048471
GO:0048488
GO:0048489
GO:0050729
GO:0050806
GO:0050808
GO:0050812
GO:0051219
GO:0051259
GO:0051262
GO:0051281
GO:0051402
GO:0051583
GO:0051585
GO:0051612
GO:0051621
GO:0051622
GO:0060079
GO:0060090
GO:0060291
GO:0060732
GO:0061024
GO:0065003
GO:0070495
GO:0070555
GO:0070840
GO:0071280
GO:0071872
GO:0071902
GO:0097435
GO:0098772
GO:0098794
GO:0099512
GO:1902957
GO:1903136
GO:1903284
GO:1903285
GO:1903421
GO:1903426
GO:1904377
GO:1904715
GO:1905606
GO:1990000
GO:2000377
HMNXSV003001866
HMNXSV003022460
Hs.21374.0.A1_3p_at
Hs.76930.1.A1_3p_a_at
ILMN_1701933
ILMN_1766165
PH_hs_0004441
TC04001383.hg
TC04002630.hg
U46901_at
g556211_3p_x_at
g556213_3p_a_at
g6806896_3p_a_at
Participates
as an input of
USP9X binds Ub-SNCA (Homo sapiens)
as a component of
USP9X:Ub-SNCA [cytosol] (Homo sapiens)
SIAH1:UBE2L6:Ub-SNCA [cytosol] (Homo sapiens)
as an output of
Ub-SNCA dissociates from the conjugating enzyme (Homo sapiens)
Other forms of this molecule
SNCA [cytosol]
p-S129-SNCA [cytosol]
SNCA [extracellular region]
SNCA A30P [cytosol]
Modified Residues
Name
ubiquitinylated lysine (monoUb [cytosol]) at unknown position
Modification
monoUb [cytosol]
PsiMod Name
ubiquitinylated lysine [MOD:01148]
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Cross References
RefSeq
XP_016864051.1
,
NP_001139527.1
,
NP_001139526.1
,
NP_000336.1
,
XP_011530510.1
,
NP_009292.1
,
XP_016864052.1
Guide to Pharmacology - Targets
3285
OpenTargets
ENSG00000145335
ENSEMBL
ENSP00000421485
,
ENSP00000343683
,
ENSP00000378437
,
ENST00000506244
,
ENST00000394986
,
ENST00000394991
,
ENSP00000378440
,
ENSP00000484044
,
ENSP00000338345
,
ENSP00000378442
,
ENST00000673718
,
ENSP00000500990
,
ENST00000508895
,
ENST00000345009
,
ENST00000618500
,
ENSP00000422238
,
ENST00000505199
,
ENSP00000396241
,
ENST00000394989
,
ENST00000420646
,
ENSP00000426955
,
ENST00000336904
ZINC - Substances
SYUA_HUMAN
ZINC target
P37840
PRO
P37840
GlyGen
P37840
PDB
6A6B
,
7V4B
,
7OZH
,
7YK8
,
8B9V
,
7YNF
,
7WMM
,
3Q28
,
7NCH
,
6CT7
,
8CYR
,
8PK2
,
7YNQ
,
4R0W
,
6L4S
,
8AEX
,
6H6B
,
7E0F
,
3Q26
,
7NCG
,
4ZNN
,
8FPT
,
8CYY
,
7YNT
,
8A4L
,
7YNN
,
6PEO
,
8HZC
,
7XO0
,
6CU7
,
8H05
,
8RQM
,
8RRR
,
7OZG
,
7V4A
,
7V49
,
6RT0
,
8PIC
,
7YNR
,
8ADU
,
7NCI
,
8CZ3
,
3Q27
,
5CRW
,
6XYP
,
7NCA
,
6UFR
,
6OSJ
,
7NCJ
,
8JEX
,
7YNS
,
8ADW
,
7V47
,
7YK2
,
8A9L
,
7XO2
,
8CZ1
,
1XQ8
,
6LRQ
,
6L1U
,
7YNL
,
8G0L
,
6RTB
,
8CZ0
,
3Q25
,
6CU8
,
4BXL
,
7L7H
,
8RI9
,
6PES
,
7WNZ
,
8JJV
,
2N0A
,
8CYS
,
6OSM
,
7NCK
,
6XYO
,
4R0U
,
8CYT
,
7V4C
,
8PJO
,
6SST
,
7V48
,
8PIX
,
8JEY
,
8ADV
,
2X6M
,
7XO1
,
7C1D
,
8HZS
,
8PK4
,
8CYV
,
4RIL
,
8CZ2
,
7XO3
,
7LC9
,
7YNG
,
8GF7
,
7UAK
,
2M55
,
8H03
,
7V4D
,
8HZB
,
9EUU
,
8CE7
,
6XYQ
,
8ADS
,
6OSL
,
8OJR
,
8OQI
,
8CZ6
,
7YNM
,
2JN5
,
3Q29
,
7WO0
,
8OG0
,
7YNP
,
8JLY
,
4RIK
,
2KKW
,
7STX
,
8CEB
,
8CYW
,
7YNO
,
6I42
,
8CYX
,
6L1T
,
8BQW
,
6SSX
,
8H04
,
7XJX
,
8BQV
HPA
ENSG00000145335-SNCA
Pharos - Targets
P37840
Orphanet
SNCA
ZINC - Predictions - Purchasable
SYUA_HUMAN
HMDB Protein
HMDBP02388
Interactors (186)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P37840 SNCA
5
SNCA [cytosol]
(R-HSA-5658500)
p-S129-SNCA [cytosol]
(R-HSA-9836432)
Ub-SNCA [cytosol]
(R-HSA-5660754)
SNCA [extracellular region]
(R-HSA-976954)
SNCA A30P [cytosol]
(R-HSA-5658569)
0.99
51
UniProt:Q9Y6H5 SNCAIP
3
PolyUb-SNCAIP [cytosol]
(R-HSA-5667104)
K63Ub-SNCAIP [cytosol]
(R-HSA-5667114)
SNCAIP [cytosol]
(R-HSA-5333629)
0.825
22
UniProt:P02649 APOE
10
APOE [endoplasmic reticulum lumen]
(R-HSA-6784908)
p-APOE [endoplasmic reticulum lumen]
(R-HSA-8956980)
APOE [extracellular region]
(R-HSA-174646)
APOE [endocytic vesicle lumen]
(R-HSA-3221641)
APOE-4 [extracellular region]
(R-HSA-9711070)
APOE [plasma membrane]
(R-HSA-174615)
APOE [clathrin-coated endocytic vesicle membrane]
(R-HSA-174651)
APOE [endosome membrane]
(R-HSA-174766)
APOE [endosome lumen]
(R-HSA-174804)
APOE [early endosome]
(R-HSA-2429687)
0.809
11
UniProt:P08107 HSP71
0.74
7
UniProt:O94811 TPPP
0.719
8
UniProt:P10636-8 MAPT
3
MAPT-8 [cytosol]
(R-HSA-9619519)
p-S262,S356,S396-MAPT-8 [cytosol]
(R-HSA-9619521)
p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol]
(R-HSA-9836400)
0.681
12
UniProt:P10909 CLU
4
CLU(23-449) [extracellular region]
(R-HSA-349732)
CLU(23-449) [platelet alpha granule lumen]
(R-HSA-349733)
CLU(228-449) [extracellular region]
(R-HSA-6810626)
CLU(23-227) [extracellular region]
(R-HSA-6810660)
0.662
4
UniProt:P05067 APP
20
APP(672-713) [extracellular region]
(R-HSA-879340)
APP(672-711) [cytosol]
(R-HSA-877188)
APP(672-711) [extracellular region]
(R-HSA-976740)
APP [endoplasmic reticulum lumen]
(R-HSA-8956696)
p-APP [endoplasmic reticulum lumen]
(R-HSA-8957012)
APP(18-770) [endosome lumen]
(R-HSA-5229077)
APP(672-711) [endosome lumen]
(R-HSA-6783333)
APP(672-713) [endosome lumen]
(R-HSA-5692993)
APP(672-770) [endosome lumen]
(R-HSA-9010082)
APP(712-770) [endosome lumen]
(R-HSA-6783331)
APP(714-770) [endosome lumen]
(R-HSA-6783325)
APP(18-671) [endosome lumen]
(R-HSA-5693003)
APP(18-770) [plasma membrane]
(R-HSA-9010038)
APP(18-770) [Golgi lumen]
(R-HSA-8871509)
APP(688-770) [plasma membrane]
(R-HSA-9010028)
APP(18-687) [extracellular region]
(R-HSA-9010033)
APP(18-770) [platelet alpha granule lumen]
(R-HSA-139835)
APP(18-770) [extracellular region]
(R-HSA-49335)
APP-C99 [cytosol]
(R-HSA-9617603)
APP(18-770) [trans-Golgi network membrane]
(R-HSA-5229136)
0.659
6
UniProt:Q07812 BAX
3
BAX [mitochondrial outer membrane]
(R-HSA-139949)
BAX activated [cytosol]
(R-HSA-139907)
BAX [cytosol]
(R-HSA-139916)
0.659
4
UniProt:O75920-2 SERF1A
0.655
4
UniProt:Q04917 YWHAH
1
YWHAH [cytosol]
(R-HSA-1445107)
0.646
4
UniProt:Q9UNE7 STUB1
1
STUB1 [cytosol]
(R-HSA-975970)
0.633
4
UniProt:P63027 VAMP2
20
VAMP2 [clathrin-sculpted monoamine transport vesicle membrane]
(R-HSA-379363)
VAMP2 [plasma membrane]
(R-HSA-210516)
VAMP2 [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane]
(R-HSA-917738)
VAMP2 [clathrin-sculpted glutamate transport vesicle membrane]
(R-HSA-210365)
VAMP2 [synaptic vesicle membrane]
(R-HSA-181517)
VAMP2(59-116) [synaptic vesicle membrane]
(R-HSA-5250891)
VAMP2(2-58) [cytosol]
(R-HSA-194815)
VAMP2(2-76) [cytosol]
(R-HSA-194802)
VAMP2(77-116) [synaptic vesicle membrane]
(R-HSA-5228355)
VAMP2(60-116) [synaptic vesicle membrane]
(R-HSA-5250615)
VAMP2(2-59) [cytosol]
(R-HSA-194797)
VAMP2(82-116) [synaptic vesicle membrane]
(R-HSA-5250961)
VAMP2(2-81) [cytosol]
(R-HSA-5250970)
VAMP2 [secretory granule membrane]
(R-HSA-376363)
VAMP2 [cytosol]
(R-HSA-9609882)
VAMP2 [endoplasmic reticulum membrane]
(R-HSA-9609886)
VAMP2 [cytoplasmic vesicle membrane]
(R-HSA-1449630)
VAMP2 [lysosomal membrane]
(R-HSA-432703)
VAMP2 [Golgi membrane]
(R-HSA-375425)
VAMP2 [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869129)
0.632
5
UniProt:Q9UI14 PRAF1
0.626
4
UniProt:P02647 APOA1
11
APOA1(25-266) [extracellular region]
(R-HSA-174720)
APOA1 [endoplasmic reticulum lumen]
(R-HSA-8956724)
p-APOA1 [endoplasmic reticulum lumen]
(R-HSA-8957081)
APOA1(25-266) [endocytic vesicle lumen]
(R-HSA-2239460)
Variant apolipoprotein AI [extracellular region]
(R-HSA-976865)
APOA1(25-266) [plasma membrane]
(R-HSA-216742)
APOA1(19-266) [extracellular region]
(R-HSA-264771)
APOA1(25-267) [endoplasmic reticulum lumen]
(R-HSA-174640)
APOA1(25-267) [early endosome]
(R-HSA-2429641)
APOA1(25-267) [cytosol]
(R-HSA-2395781)
APOA1(25-266) [secretory granule lumen]
(R-HSA-350761)
0.623
3
UniProt:Q7Z7K6 CENPV
0.61
4
UniProt:P00519 ABL1
6
p-S456-ABL1 [nucleoplasm]
(R-HSA-5686576)
ABL1 [nucleoplasm]
(R-HSA-5686579)
p-Y226,Y393-ABL1 [cytosol]
(R-HSA-8942610)
ABL1 [cytosol]
(R-HSA-375987)
p-Y226,Y393-ABL1 [nucleoplasm]
(R-HSA-8985251)
p-Y393-ABL1 [cytosol]
(R-HSA-9865161)
0.602
3
GDP [ChEBI:17552]
7
GDP [lysosomal membrane]
(R-ALL-9628545)
GDP [cytoplasmic vesicle membrane]
(R-ALL-1996292)
GDP [cilium]
(R-ALL-5617810)
GDP [platelet dense granule lumen]
(R-ALL-114622)
GDP [nucleoplasm]
(R-ALL-111349)
GDP [plasma membrane]
(R-ALL-114549)
GDP [endoplasmic reticulum lumen]
(R-ALL-1467290)
0.582
5
UniProt:P00441 SOD1
5
2xHC-SOD1 [cytosol]
(R-HSA-3299726)
SOD1 [cytosol]
(R-HSA-350697)
2xHC-SOD1 [mitochondrial intermembrane space]
(R-HSA-3777108)
SOD1 [mitochondrial intermembrane space]
(R-HSA-3777082)
SOD1 [extracellular region]
(R-HSA-350705)
0.567
9
UniProt:P00519-1 ABL1
0.558
6
UniProt:P0DTC9 N
13
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [cytosol]
(R-COV-9729340)
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-COV-9729341)
ADPr-p-11S,2T-metR95,177-N [cytosol]
(R-COV-9729275)
p-11S,2T-metR95,177-N [cytosol]
(R-COV-9729308)
p-11S,2T-N [cytosol]
(R-COV-9729264)
p-8S,2T-N [cytosol]
(R-COV-9729277)
p-8S-N [cytosol]
(R-COV-9729335)
p-S188,206-N [cytosol]
(R-COV-9729324)
N [cytosol]
(R-COV-9694300)
SUMO1-K62,ADPr-,p-11S,2T,met-R95,177,Ac-K375-N [cytosol]
(R-COV-9756489)
N [plasma membrane]
(R-COV-9694356)
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [nucleolus]
(R-COV-9729339)
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [plasma membrane]
(R-COV-9729325)
0.558
2
UniProt:Q16650 TBR1
0.556
3
UniProt:Q8IUI8 CRLF3
0.556
3
UniProt:Q9UHY8 FEZ2
0.556
3
UniProt:O60479 DLX3
0.556
3
UniProt:Q07817 BCL2L1
2
BCL2L1 [cytosol]
(R-HSA-50771)
BCL2L1 [mitochondrial outer membrane]
(R-HSA-114236)
0.556
3
UniProt:O15392 BIRC5
3
BIRC5 [cytosol]
(R-HSA-50851)
BIRC5 [nucleoplasm]
(R-HSA-4655344)
ub-BIRC5 [cytosol]
(R-HSA-8955933)
0.556
3
UniProt:P68363 TUBA1B
9
TUBA1B [cytosol]
(R-HSA-191691)
TUBA1B [axonemal microtubule]
(R-HSA-5610434)
TUBA1B(1-450) [cytosol]
(R-HSA-8955581)
Polyglutamyl-TUBA1B [cytosol]
(R-HSA-8867435)
L-isoglutamyl polyglycyl-TUBA1B [cytosol]
(R-HSA-8867436)
TUBA1B unfolded [cytosol]
(R-HSA-392781)
TUBA1B folding intermediate [cytosol]
(R-HSA-392797)
Ac K40 TUBA1B [axonemal microtubule]
(R-HSA-5624854)
AcK-TUBA1B [cytosol]
(R-HSA-5618285)
0.556
3
UniProt:Q8WVJ9 TWIST2
1
TWIST2 [nucleoplasm]
(R-HSA-445444)
0.556
3
UniProt:Q9H2C1 LHX5
0.556
3
UniProt:P62826 RAN
2
RAN [cytosol]
(R-HSA-165540)
RAN [nucleoplasm]
(R-HSA-165528)
0.556
3
UniProt:Q8N895 ZN366
0.556
3
UniProt:P17980 PSMC3
5
PSMC3 [cytosol]
(R-HSA-68774)
PSMC3 [nucleoplasm]
(R-HSA-174313)
PSMC3 [secretory granule lumen]
(R-HSA-6800917)
PSMC3 [extracellular region]
(R-HSA-6806496)
PSMC3 [ficolin-1-rich granule lumen]
(R-HSA-6800429)
0.556
6
UniProt:Q9HCE7-2 SMURF1
0.556
3
UniProt:P10636-6 MAPT
0.556
3
UniProt:O00560 SDCBP
3
SDCBP [cytosol]
(R-HSA-373639)
SDCBP [azurophil granule lumen]
(R-HSA-6799372)
SDCBP [extracellular region]
(R-HSA-6806206)
0.556
3
UniProt:Q6VY07 PACS1
1
PACS1 [cytosol]
(R-HSA-167634)
0.556
3
UniProt:Q71DI3 H3C15
20
2xAcK-HIST2H3A [nucleoplasm]
(R-HSA-427525)
Me1K5-HIST2H3A [nucleoplasm]
(R-HSA-9677679)
Me2aR27-HIST2H3A [nucleoplasm]
(R-HSA-5229057)
Me2aR18-HIST2H3A [nucleoplasm]
(R-HSA-5229063)
Me2sR9-HIST2H3A [nucleoplasm]
(R-HSA-5211327)
Me2sR3-HIST2H3A [nucleoplasm]
(R-HSA-5218930)
AcK9,14-p-S10-HIST2H3A [nucleoplasm]
(R-HSA-8870892)
AcK14,18,79-p-S10-HIST2H3A [nucleoplasm]
(R-HSA-8871273)
AcK9,14,18-p-S10,T11-HIST2H3A [nucleoplasm]
(R-HSA-8871304)
AcK14,18-p-S10,T11-HIST2H3A [nucleoplasm]
(R-HSA-8871292)
AcK9,14,18,79-p-S10,T11-HIST2H3A [nucleoplasm]
(R-HSA-8865607)
AcK14,18-p-S10-HIST2H3A [nucleoplasm]
(R-HSA-8871296)
AcK14,18,79-p-T11-HIST2H3A [nucleoplasm]
(R-HSA-8871290)
AcK14,18-p-T11-HIST2H3A [nucleoplasm]
(R-HSA-8871302)
AcK14,18,79-p-S10,T11-HIST2H3A [nucleoplasm]
(R-HSA-8871289)
Me2K28-HIST2H3A [nucleoplasm]
(R-HSA-4754197)
MeK37-HIST2H3A [nucleoplasm]
(R-HSA-4722131)
MeK80-HIST2H3A [nucleoplasm]
(R-HSA-5649805)
Me3K80-HIST2H3A [nucleoplasm]
(R-HSA-5649798)
Me2K80-HIST2H3A [nucleoplasm]
(R-HSA-5649803)
0.556
3
UniProt:O00203 AP3B1
4
AP3B1 [Golgi membrane]
(R-HSA-434335)
AP3B1 [cytoplasmic vesicle membrane]
(R-HSA-434197)
AP3B1(1-859)-BRAF(381-766) fusion [cytosol]
(R-HSA-6802269)
AP3B1(1-859)-p-BRAF(381-766) fusion [cytosol]
(R-HSA-6802516)
0.556
3
UniProt:Q8N6F8 MET27
0.556
3
UniProt:Q9Y483-4 MTF2
0.556
3
UniProt:Q9Y3D2 MSRB2
1
MSRB2 [cytosol]
(R-HSA-5676906)
0.556
3
UniProt:Q96D59 RN183
0.556
3
UniProt:P46379-2 BAG6
0.556
3
UniProt:P55212 CASP6
5
CASP6(194-293) [cytosol]
(R-HSA-266128)
CASP6(24-179) [cytosol]
(R-HSA-350313)
CASP6(24-179) [nucleoplasm]
(R-HSA-352247)
CASP6(194-293) [nucleoplasm]
(R-HSA-352246)
CASP6 (1-293) [cytosol]
(R-HSA-6798132)
0.556
3
UniProt:Q8N5U6 RNF10
0.556
3
UniProt:Q9H0Y0 ATG10
2
GlyK166-ATG10 [cytosol]
(R-HSA-5683572)
ATG10 [cytosol]
(R-HSA-5671733)
0.556
3
UniProt:O96013-2 PAK4
0.556
3
UniProt:P57052 RBM11
0.556
3
UniProt:Q6PCB6 ABHD17C
1
ABHD17C [plasma membrane]
(R-HSA-9647774)
0.556
3
UniProt:Q16352 AINX
0.556
3
UniProt:Q8N594 MPND
0.556
3
UniProt:P23497-2 SP100
0.556
3
UniProt:O75400-2 PRPF40A
0.556
3
UniProt:Q9UIH9 KLF15
1
KLF15 [nucleoplasm]
(R-HSA-8878735)
0.556
3
UniProt:Q8TC29 ENKUR
0.556
3
UniProt:Q9HCC6 HES4
0.556
3
UniProt:Q6ZNA4-2 Q6ZNA42
0.556
3
UniProt:O75398 DEAF1
0.556
3
UniProt:P18847 ATF3
1
ATF3 [nucleoplasm]
(R-HSA-535543)
0.556
3
UniProt:P07948 LYN
7
LYN [cytosol]
(R-HSA-354251)
MyrG2-PalmC3-LYN [plasma membrane]
(R-HSA-9606875)
p-Y397-LYN [plasma membrane]
(R-HSA-2454229)
p-Y397-LYN [cytosol]
(R-HSA-8942608)
LYN [plasma membrane]
(R-HSA-197943)
MyrG2-PalmC3-LYN [endocytic vesicle membrane]
(R-HSA-9705728)
MyrG2-PalmC3-LYN [lysosomal membrane]
(R-HSA-9707903)
0.556
3
UniProt:O43236 SEPT4
0.556
3
UniProt:Q9NR21-5 PARP11
0.556
3
UniProt:Q9BSL1 UBAC1
1
UBAC1 [cytosol]
(R-HSA-8851644)
0.556
3
UniProt:O60260-5 PRKN
0.556
8
UniProt:P63010-2 AP2B1
0.556
3
UniProt:Q9H0E2 TOLLIP
4
TOLLIP [cytosol]
(R-HSA-446885)
TOLLIP [specific granule lumen]
(R-HSA-6799719)
TOLLIP [extracellular region]
(R-HSA-6800448)
TOLLIP [azurophil granule lumen]
(R-HSA-6799709)
0.556
3
UniProt:Q96FW1 OTUB1
2
OTUB1 [nucleoplasm]
(R-HSA-6783242)
OTUB1 [cytosol]
(R-HSA-933411)
0.556
3
UniProt:Q13113 PDZ1I
0.556
3
UniProt:Q6ZTN6-2 ANKRD13D
0.556
3
UniProt:O14713 ITBP1
0.556
3
UniProt:Q16740 CLPP
1
CLPP [mitochondrial matrix]
(R-HSA-9838002)
0.556
3
UniProt:P13473-2 P134732
0.556
3
IntAct:EBI-25849442 CCSB
0.556
3
UniProt:Q0VDC6 Q0VDC6
0.556
3
UniProt:Q8NDP9 Q8NDP9
0.556
3
IntAct:EBI-25830852 RZPDO839G03145
0.556
3
UniProt:Q6DN90-2 Q6DN902
0.556
3
UniProt:Q9ULX5 RN112
0.556
3
UniProt:Q8N5S9-2 Q8N5S92
0.556
3
UniProt:O75446 SAP30
1
SAP30 [nucleoplasm]
(R-HSA-351693)
0.556
3
UniProt:P62191 PSMC1
2
PSMC1 [cytosol]
(R-HSA-68768)
PSMC1 [nucleoplasm]
(R-HSA-174338)
0.556
3
UniProt:Q8TBB1 LNX1
1
LNX1 [cytosol]
(R-HSA-8851641)
0.556
3
UniProt:Q13702-2 Q137022
0.556
3
UniProt:Q8WUW1 BRK1
1
BRK1 [cytosol]
(R-HSA-1671645)
0.556
3
UniProt:Q9NV79 PCMD2
0.556
3
UniProt:O00308 WWP2
1
WWP2 [cytosol]
(R-HSA-6807279)
0.556
3
UniProt:P28347-2 TEAD1
0.556
3
UniProt:Q6PIV2 FOXR1
0.556
3
UniProt:Q92797-2 Q927972
0.556
3
UniProt:Q9BYQ4 KRTAP9-2
1
KRTAP9-2 [cytosol]
(R-HSA-6809965)
0.556
3
UniProt:P06241-3 FYN
0.556
3
UniProt:O75604-3 USP2
0.556
3
UniProt:Q9UNS2 COPS3
2
COPS3 [nucleoplasm]
(R-HSA-5697017)
COPS3 [cytosol]
(R-HSA-416973)
0.556
3
UniProt:Q8N488 RYBP
1
RYBP [nucleoplasm]
(R-HSA-8937975)
0.556
3
UniProt:P62879 GNB2
4
GNB2 [cytosol]
(R-HSA-6814421)
Partially folded GNB2 [cytosol]
(R-HSA-8850536)
Unfolded GNB2 [cytosol]
(R-HSA-6814202)
GNB2 [plasma membrane]
(R-HSA-164335)
0.556
3
UniProt:Q92876 KLK6
0.556
3
UniProt:P07437 TUBB
3
TUBB [extracellular region]
(R-HSA-380317)
TUBB [azurophil granule lumen]
(R-HSA-6799370)
TUBB [cytosol]
(R-HSA-9020816)
0.556
3
UniProt:Q99932-2 SPAG8
0.556
3
UniProt:P62987 UBA52
20
UBA52(1-76) [endocytic vesicle membrane]
(R-HSA-939236)
Ub-33-UBA52(1-76) [mitochondrial outer membrane]
(R-HSA-6783187)
Ub-63-UBA52(1-76) [mitochondrial outer membrane]
(R-HSA-6783039)
Ub-6-UBA52(1-76) [mitochondrial outer membrane]
(R-HSA-6783072)
Ub-11-UBA52(1-76) [mitochondrial outer membrane]
(R-HSA-6783059)
Ub-48-UBA52(1-76) [mitochondrial outer membrane]
(R-HSA-6783049)
Ub-29-UBA52(1-76) [mitochondrial outer membrane]
(R-HSA-6783030)
Ub-63-UBA52(1-76) [cytosol]
(R-HSA-939169)
UBA52(1-76) [lysosomal lumen]
(R-HSA-9660000)
UBA52(1-76) [cytosol]
(R-HSA-939203)
p-S65-UBA52(1-76) [mitochondrial outer membrane]
(R-HSA-9834996)
Ub-48-UBA52(1-76) [cytosol]
(R-HSA-939250)
UBA52(1-76) [mitochondrial outer membrane]
(R-HSA-9834955)
UBA52(1-76) [late endosome lumen]
(R-HSA-9660003)
Ub-6-UBA52(1-76) [nucleoplasm]
(R-HSA-6782616)
Ub-63-UBA52(1-76) [nucleoplasm]
(R-HSA-6782530)
Ub-48-UBA52(1-76) [nucleoplasm]
(R-HSA-5683034)
UBA52(1-76) [nucleoplasm]
(R-HSA-939844)
Ub-11-UBA52(1-76) [cytosol]
(R-HSA-3095931)
Ub-63-UBA52(1-76) [plasma membrane]
(R-HSA-939851)
0.556
3
UniProt:P06241 FYN
6
FYN [cytosol]
(R-HSA-200917)
MyrG-p-Y420-FYN [plasma membrane]
(R-HSA-1810410)
p-Y420-FYN [cytosol]
(R-HSA-391821)
MyrG2-PalmC3,6-FYN [plasma membrane]
(R-HSA-9606873)
p-Y531-FYN [cytosol]
(R-HSA-391819)
p-S21,Y420-FYN [cytosol]
(R-HSA-5218745)
0.556
3
UniProt:Q96RL1-2 UIMC1
0.556
3
UniProt:O43167-2 O431672
0.556
3
UniProt:Q9Y2M5 KLHL20
1
KLHL20 [cytosol]
(R-HSA-976032)
0.556
3
UniProt:O15381-5 O153815
0.556
3
UniProt:A2RU56 A2RU56
0.556
3
UniProt:A4FUJ8 A4FUJ8
0.556
3
UniProt:P02795 MT2A
1
MT2A [cytosol]
(R-HSA-1031707)
0.556
3
UniProt:P48730-2 CSNK1D
0.556
3
UniProt:Q0P5N6 ARL16
0.556
3
UniProt:P02792 FTL
4
FTL [endocytic vesicle lumen]
(R-HSA-2299671)
FTL [extracellular region]
(R-HSA-2187214)
FTL [azurophil granule lumen]
(R-HSA-6799149)
FTL [cytosol]
(R-HSA-434215)
0.556
3
UniProt:Q6ZR37 PKHG7
0.556
3
UniProt:Q15554-4 Q155544
0.556
3
UniProt:Q04323-2 UBXN1
0.556
3
UniProt:Q9UJ41-4 RABGEF1
0.556
3
UniProt:Q8WUU4 ZN296
0.556
3
UniProt:Q5S007 LRRK2
1
LRRK2 [cytosol]
(R-HSA-5661173)
0.556
6
IntAct:EBI-25875427 CCSB
0.556
3
UniProt:Q9GZS3 SKIC8
2
WDR61 [cytosol]
(R-HSA-8931534)
WDR61 [nucleoplasm]
(R-HSA-8866696)
0.556
3
UniProt:Q2NKQ1-4 SGSM1
0.556
3
UniProt:P40337-2 VHL
0.556
3
UniProt:P68431 HIST1H3G
20
2xAcK-HIST1H3A [nucleoplasm]
(R-HSA-427507)
Me1K5-H3C1 [nucleoplasm]
(R-HSA-9677683)
Ack-Me3K5-HIST1H3A [nucleoplasm]
(R-HSA-4551293)
AcK-Me3K10-HIST1H3A [nucleoplasm]
(R-HSA-4551291)
AcK-Me3K28-HIST1H3A [nucleoplasm]
(R-HSA-4551292)
Me2aR27-HIST1H3A [nucleoplasm]
(R-HSA-5229052)
Me2aR18-HIST1H3A [nucleoplasm]
(R-HSA-5229062)
Me2sR9-HIST1H3A [nucleoplasm]
(R-HSA-5211328)
Me2sR3-HIST1H3A [nucleoplasm]
(R-HSA-5218935)
AcK9,14-p-S10-HIST1H3A [nucleoplasm]
(R-HSA-8870893)
AcK14,18,79-p-S10-HIST1H3A [nucleoplasm]
(R-HSA-8871271)
AcK9,14,18-p-S10,T11-HIST1H3A [nucleoplasm]
(R-HSA-8871306)
AcK14,18-p-S10,T11-HIST1H3A [nucleoplasm]
(R-HSA-8871294)
AcK9,14,18,79-p-S10,T11-HIST1H3A [nucleoplasm]
(R-HSA-8865596)
AcK14,18-p-S10-HIST1H3A [nucleoplasm]
(R-HSA-8871295)
AcK14,18,79-p-T11-HIST1H3A [nucleoplasm]
(R-HSA-8871288)
AcK14,18-p-T11-HIST1H3A [nucleoplasm]
(R-HSA-8871299)
AcK14,18,79-p-S10,T11-HIST1H3A [nucleoplasm]
(R-HSA-8871286)
Me2K28-HIST1H3A [nucleoplasm]
(R-HSA-4754193)
MeK37-HIST1H3A [nucleoplasm]
(R-HSA-4722135)
0.556
3
UniProt:O95777 LSM8
1
LSM8 [nucleoplasm]
(R-HSA-6806779)
0.556
3
UniProt:Q8NBB4-2 ZSCAN1
0.556
3
UniProt:Q9UPM6 LHX6
0.556
3
UniProt:P99999 CYCS
6
CYCS [cytosol]
(R-HSA-53259)
CYCS [mitochondrial intermembrane space]
(R-HSA-114244)
Cytochrome c (oxidised) [mitochondrial inner membrane]
(R-HSA-352607)
Cytochrome c (reduced) [mitochondrial inner membrane]
(R-HSA-352609)
apo-CYCS [mitochondrial inner membrane]
(R-HSA-352608)
AcK-CYCS [mitochondrial intermembrane space]
(R-HSA-5688308)
0.556
3
UniProt:Q5SZD1 CF141
0.556
3
UniProt:Q8TCT7-2 SPPL2B
0.556
3
UniProt:P17252 PRKCA
8
PRKCA [cytosol]
(R-HSA-58196)
PRKCA [plasma membrane]
(R-HSA-156469)
pT497,T638,S657-PRKCA [plasma membrane]
(R-HSA-4332340)
p-T497,T638,S657-PRKCA [nucleoplasm]
(R-HSA-5223292)
p-T497-PRKCA [cytosol]
(R-HSA-5218731)
p-T497,T638,S657-PRKCA [cytosol]
(R-HSA-4332337)
PRKCA [photoreceptor disc membrane]
(R-HSA-2648987)
PRKCA [nucleoplasm]
(R-HSA-450530)
0.556
3
UniProt:Q13501 SQSTM1
7
SQSTM1 [cytosol]
(R-HSA-193937)
SQSTM1 [nucleoplasm]
(R-HSA-210961)
ub K420 p-S349 SQSTM1 [cytosol]
(R-HSA-9766536)
p-S349 SQSTM1 [cytosol]
(R-HSA-9766524)
K7 ub-SQSTM1 [cytosol]
(R-HSA-9759088)
SQSTM1(2-251)-ALK(1058-1620) fusion [cytosol]
(R-HSA-9711954)
SQSTM1(2-251)-p-7Y-ALK(1058-1620) fusion [cytosol]
(R-HSA-9711967)
0.556
3
UniProt:Q8WXK3 ASB13
1
ASB13 [cytosol]
(R-HSA-975427)
0.556
3
UniProt:Q8IYW5 RNF168
2
RNF168 [nucleoplasm]
(R-HSA-4551605)
monoSUMO1-RNF168 [nucleoplasm]
(R-HSA-4551750)
0.556
3
UniProt:Q9UBQ0-2 VPS29
0.556
3
UniProt:Q96JM7-2 L3MBTL3
0.556
3
UniProt:O00472 ELL2
1
ELL2 [nucleoplasm]
(R-HSA-6807506)
0.556
3
UniProt:Q8NHS9 SPT22
0.556
3
UniProt:O00471 EXOC5
2
EXOC5 [cytosol]
(R-HSA-265045)
EXOC5 [cytosol]
(R-HSA-5623383)
0.556
3
UniProt:Q68EA5 ZNF57
0.556
3
UniProt:Q8TD91-2 MAGEC3
0.556
3
IntAct:EBI-25835277 CCSB
0.556
3
UniProt:P80217-2 IFI35
0.556
3
UniProt:Q9NP61 ARFGAP3
1
ARFGAP3 [cytosol]
(R-HSA-6807740)
0.556
3
UniProt:Q8WVV9-3 Q8WVV93
0.556
3
UniProt:Q86WS3 OOSP2
0.556
3
IntAct:EBI-25831191 CCSB
0.556
3
UniProt:Q8WVD3 RNF138
1
RNF138 [cytosol]
(R-HSA-976008)
0.556
3
UniProt:O15205 UBD
1
UBD [cytosol]
(R-HSA-8956123)
0.556
3
UniProt:Q6GQQ9-2 Q6GQQ92
0.556
3
UniProt:Q8TDB4 HUMMR
0.556
3
UniProt:P62158 CALM
0.556
3
UniProt:Q9BR01-2 Q9BR012
0.556
3
UniProt:O75886 STAM2
2
Ub-STAM2 [cytosol]
(R-HSA-6782781)
STAM2 [cytosol]
(R-HSA-182965)
0.556
3
UniProt:O00746 NME4
1
NME4 [mitochondrial inner membrane]
(R-HSA-60026)
0.556
3
UniProt:Q02156 PRKCE
2
p-T566,T710,S729-PRKCE [plasma membrane]
(R-HSA-198260)
PRKCE [cytosol]
(R-HSA-58202)
0.556
3
UniProt:Q13569 TDG
3
TDG [nucleoplasm]
(R-HSA-65812)
monoSUMO1-K330-TDG [nucleoplasm]
(R-HSA-4551718)
polySUMO2,3-K330-TDG [nucleoplasm]
(R-HSA-4551628)
0.556
3
UniProt:A8K878 A8K878
0.556
3
UniProt:Q8N6T3-3 ARFGAP1
0.556
3
UniProt:A0AVK6 E2F8
1
E2F8 [nucleoplasm]
(R-HSA-8952990)
0.556
3
UniProt:Q9HD42 CHMP1A
1
CHMP1A [cytosol]
(R-HSA-917721)
0.556
3
UniProt:P19474 TRIM21
1
TRIM21 [cytosol]
(R-HSA-976051)
0.556
3
UniProt:Q9BYZ2 LDHAL6B
1
LDHAL6B [mitochondrial matrix]
(R-HSA-6807613)
0.556
3
UniProt:Q969S8 HDAC10
1
HDAC10 [nucleoplasm]
(R-HSA-351579)
0.556
3
UniProt:Q16143 SNCB
1
SNCB [cytosol]
(R-HSA-5660390)
0.556
3
UniProt:Q96NC0 ZMAT2
1
ZMAT2 [nucleoplasm]
(R-HSA-9770248)
0.556
3
UniProt:Q8N448 LNX2
0.556
3
UniProt:Q8N988-2 ZNF557
0.556
3
UniProt:P09017 HOXC4
1
HOXC4 [nucleoplasm]
(R-HSA-5617871)
0.556
3
UniProt:O75530-2 EED
0.556
3
UniProt:O75925 PIAS1
1
PIAS1 [nucleoplasm]
(R-HSA-877307)
0.556
3
UniProt:P00533 EGFR
20
p-6Y-EGFR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869138)
p-5Y-EGFRvIII [plasma membrane]
(R-HSA-1248649)
EGFRvIII [plasma membrane]
(R-HSA-1214162)
p-6Y-EGFR E746_A750del;T790M [plasma membrane]
(R-HSA-1182985)
p-6Y-EGFR L858R;T790M [plasma membrane]
(R-HSA-1182984)
p-6Y-EGFR A767_V769dup [plasma membrane]
(R-HSA-1996343)
p-6Y-EGFR N771_H773dup [plasma membrane]
(R-HSA-1996342)
p-6Y-EGFR K739_I744dup [plasma membrane]
(R-HSA-1996346)
p-6Y-EGFR D770_N771insNPG [plasma membrane]
(R-HSA-1996335)
p-6Y-EGFR E746_A750del [plasma membrane]
(R-HSA-1181214)
p-6Y-EGFR L858R [plasma membrane]
(R-HSA-1173211)
p-6Y-EGFR G719S [plasma membrane]
(R-HSA-1169417)
p-6Y-EGFR L747_P753delinsS [plasma membrane]
(R-HSA-1228038)
p-6Y-EGFR L747_A750delinsP [plasma membrane]
(R-HSA-1228044)
p-6Y-EGFR L747_T751del [plasma membrane]
(R-HSA-1228041)
p-6Y-EGFR L747_S752del [plasma membrane]
(R-HSA-1228040)
p-6Y-EGFR L747_T751delinsP [plasma membrane]
(R-HSA-1228042)
p-6Y-EGFR E746_T751delinsA [plasma membrane]
(R-HSA-1228037)
p-6Y-EGFR E746_S752delinsV [plasma membrane]
(R-HSA-1228039)
p-6Y-EGFR L861Q [plasma membrane]
(R-HSA-1177541)
0.553
2
UniProt:Q5QJC9
1
Bag5 [cytosol]
(R-RNO-5255453)
0.548
3
UniProt:P49841 GSK3B
4
GSK3B [cytosol]
(R-HSA-2997551)
p-S9-GSK3B [cytosol]
(R-HSA-3149577)
GSK3B [nucleoplasm]
(R-HSA-2022823)
GSK3B del304-316 [cytosol]
(R-HSA-5339682)
0.544
2
UniProt:P42858 HTT
1
HTT [nucleoplasm]
(R-HSA-9023590)
0.543
4
UniProt:Q01959 SLC6A3
5
SLC6A3 [plasma membrane]
(R-HSA-379482)
SLC6A3 L368Q [plasma membrane]
(R-HSA-5660710)
SLC6A3 L224P [plasma membrane]
(R-HSA-5660718)
SLC6A3 P395L [plasma membrane]
(R-HSA-5660716)
SLC6A3 R521W [plasma membrane]
(R-HSA-5660729)
0.539
3
UniProt:Q9WV55
4
Vapa [cytosol]
(R-MMU-9609920)
Vapa [endoplasmic reticulum membrane]
(R-MMU-429677)
Vapa [plasma membrane]
(R-MMU-6806269)
Vapa [azurophil granule membrane]
(R-MMU-6799364)
0.527
2
UniProt:P0CG48 UBC
20
UBC(381-456) [endocytic vesicle membrane]
(R-HSA-939218)
UBC(533-608) [endocytic vesicle membrane]
(R-HSA-939220)
UBC(609-684) [endocytic vesicle membrane]
(R-HSA-939223)
UBC(457-532) [endocytic vesicle membrane]
(R-HSA-939195)
UBC(153-228) [endocytic vesicle membrane]
(R-HSA-939194)
UBC(305-380) [endocytic vesicle membrane]
(R-HSA-939228)
UBC(229-304) [endocytic vesicle membrane]
(R-HSA-939177)
UBC(77-152) [endocytic vesicle membrane]
(R-HSA-939210)
UBC(1-76) [endocytic vesicle membrane]
(R-HSA-939245)
Ub-565-UBC(533-608) [mitochondrial outer membrane]
(R-HSA-6783166)
Ub-337-UBC(305-380) [mitochondrial outer membrane]
(R-HSA-6783121)
Ub-185-UBC(153-228) [mitochondrial outer membrane]
(R-HSA-6783154)
Ub-261-UBC(229-304) [mitochondrial outer membrane]
(R-HSA-6783028)
Ub-413-UBC(381-456) [mitochondrial outer membrane]
(R-HSA-6783061)
Ub-109-UBC(77-152) [mitochondrial outer membrane]
(R-HSA-6783158)
Ub-641-UBC(609-684) [mitochondrial outer membrane]
(R-HSA-6783182)
Ub-33-UBC(1-76) [mitochondrial outer membrane]
(R-HSA-6783073)
Ub-489-UBC(457-532) [mitochondrial outer membrane]
(R-HSA-6783078)
Ub-291-UBC(229-304) [mitochondrial outer membrane]
(R-HSA-6783193)
Ub-595-UBC(533-608) [mitochondrial outer membrane]
(R-HSA-6783130)
0.524
2
UniProt:Q9Y6H5-2 SNCAIP
1
SNCAIP-1A [cytosol]
(R-HSA-5667110)
0.524
2
UniProt:Q61327
1
SLC6A3 [plasma membrane]
(R-MMU-379482)
0.518
5
UniProt:O88507
1
Cntfr [plasma membrane]
(R-MMU-5696438)
0.512
4
UniProt:P00414 MT-CO3
1
MT-CO3 [mitochondrial inner membrane]
(R-HSA-164312)
0.508
3
UniProt:P60880-2 SNAP25
0.499
3
UniProt:Q16623 STX1A
5
STX1A [plasma membrane]
(R-HSA-449128)
STX1A(?-288) [plasma membrane]
(R-HSA-5246518)
STX1A(1-?) [cytosol]
(R-HSA-3065964)
STX1A [cytosol]
(R-HSA-9609866)
STX1A [endoplasmic reticulum membrane]
(R-HSA-9609878)
0.499
2
UniProt:P00519-2 ABL1
0.463
5
UniProt:P00520 Abl1
7
phospho-p-S456-ABL1 [nucleoplasm]
(R-MMU-5686576)
ABL1 [nucleoplasm]
(R-MMU-5686579)
p-Y226,Y393-ABL1 [cytosol]
(R-MMU-8942610)
ABL1 [cytosol]
(R-MMU-375987)
p-Y226,Y393-ABL1 [nucleoplasm]
(R-MMU-8985251)
phospho-p-Y393-ABL1 [cytosol]
(R-MMU-9865161)
Abl1 [cytosol]
(R-MMU-449189)
0.463
2
UniProt:Q08406
1
Cntfr [plasma membrane]
(R-RNO-5696438)
0.462
2
UniProt:P54253 ATX1
0.462
3
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