AKR1A1 reduces D-glucuronate to L-gulonate

Stable Identifier
R-HSA-5661256
Type
Reaction
Species
Homo sapiens
Compartment
Synonyms
D-glucuronate + NADPH + H+ => L-gulonate + NADP+
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Cytosolic AKR1A1 (Aldo-keto reductase family 1 member A1) catalyzes the reduction by NADPH of D-glucuronate to L-gulonate (Barski et al. 1995).

Literature References
PubMed ID Title Journal Year
7669785 Mechanism of human aldehyde reductase: characterization of the active site pocket

Gabbay, KH, Barski, OA, Bohren, KM, Grimshaw, CE

Biochemistry 1995
Participants
Participates
Catalyst Activity

L-glucuronate reductase activity of AKR1A1 [cytosol]

Orthologous Events
Authored
Reviewed
Created
Cite Us!