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RHPN1 [cytosol]
Stable Identifier
R-HSA-5667017
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Rhophilin-1
Icon
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase Effectors (Homo sapiens)
RHO GTPases Activate Rhotekin and Rhophilins (Homo sapiens)
RHOA:GTP binds RHPN1 or RHPN2 (Homo sapiens)
RHOA:GTP:RHPN1,RHPN2 [plasma membrane] (Homo sapiens)
RHPN1,RHPN2 [cytosol] (Homo sapiens)
RHPN1 [cytosol] (Homo sapiens)
RHPN1,RHPN2 [cytosol] (Homo sapiens)
RHPN1 [cytosol] (Homo sapiens)
ROPN1 binds RHOA:GTP:RHPN1 (Homo sapiens)
RHOA:GTP:RHPN1 [plasma membrane] (Homo sapiens)
RHPN1 [cytosol] (Homo sapiens)
RHOA:GTP:RHPN1:ROPN1 [plasma membrane] (Homo sapiens)
RHOA:GTP:RHPN1 [plasma membrane] (Homo sapiens)
RHPN1 [cytosol] (Homo sapiens)
RHO GTPase cycle (Homo sapiens)
RHOA GTPase cycle (Homo sapiens)
RHOA binds effectors at the plasma membrane (Homo sapiens)
RHOA plasma membrane effectors [cytosol] (Homo sapiens)
RHPN1 [cytosol] (Homo sapiens)
RHOA:GTP:cytosolic RHOA effectors [plasma membrane] (Homo sapiens)
RHOA plasma membrane effectors [cytosol] (Homo sapiens)
RHPN1 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q8TCX5 RHPN1
Gene Names
RHPN1, KIAA1929
Chain
chain:1-670
Reference Genes
BioGPS Gene:114822 RHPN1
COSMIC (genes):RHPN1 RHPN1
CTD Gene:114822 RHPN1
dbSNP Gene:114822 RHPN1
ENSEMBL:ENSG00000158106 RHPN1
HGNC:19973 RHPN1
Monarch:114822 RHPN1
NCBI Gene:114822 RHPN1
OMIM:601031 RHPN1
UCSC:Q8TCX5 RHPN1
Reference Transcript
RefSeq:NM_052924.2 RHPN1
Other Identifiers
114822
11728017_a_at
11728018_at
17073340
228405_PM_at
228405_at
235998_PM_at
235998_at
3119573
3119574
3119579
3119580
3119581
3119582
3119583
3119585
3119586
3119587
3119588
3119590
3119591
3119592
3119593
3119594
3119595
3119596
3119598
3119600
3119601
3119602
3119603
3119604
3119605
3119606
3119607
3119608
62216_at
74223_at
8148621
A_14_P112959
A_23_P315386
A_23_P87432
A_23_P87435
A_33_P3387616
GE80358
GO:0005515
GO:0005829
GO:0007165
GO:0051497
HMNXSV003037730
Hs.128081.0.A1_3p_at
Hs.149152.0.A1_3p_at
ILMN_1742003
PH_hs_0008978
TC08000820.hg
Participates
as a member of
RHOA plasma membrane effectors [cytosol] (Homo sapiens)
RHPN1,RHPN2 [cytosol] (Homo sapiens)
as a component of
RHOA:GTP:RHPN1 [plasma membrane] (Homo sapiens)
Inferred To
Rhpn1 [cytosol]
(Mus musculus)
Rhpn1 [cytosol]
(Rattus norvegicus)
RHPN1 [cytosol]
(Bos taurus)
RHPN1 [cytosol]
(Canis familiaris)
RHPN1 [cytosol]
(Gallus gallus)
RHPN1 [cytosol]
(Sus scrofa)
Rhp [cytosol]
(Drosophila melanogaster)
rhpn1 [cytosol]
(Xenopus tropicalis)
Cross References
ENSEMBL
ENST00000289013
,
ENSP00000289013
OpenTargets
ENSG00000158106
HPA
ENSG00000158106-RHPN1
PRO
Q8TCX5
Pharos - Targets
Q8TCX5
HMDB Protein
HMDBP08553
Interactors (12)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q08379 GOLGA2
3
p-S37-GOLGA2 [Golgi membrane]
(R-HSA-2172179)
GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-2167933)
GOLGA2 [Golgi membrane]
(R-HSA-6808764)
0.742
5
UniProt:P07196 NEFL
1
NEFL [cytosol]
(R-HSA-432284)
0.556
3
UniProt:O76024 WFS1
3
WFS1 [endoplasmic reticulum lumen]
(R-HSA-8956747)
p-WFS1 [endoplasmic reticulum lumen]
(R-HSA-8956998)
WFS1 [endoplasmic reticulum membrane]
(R-HSA-535474)
0.556
3
UniProt:P14373 TRIM27
2
TRIM27 [cytosol]
(R-HSA-8851002)
TRIM27 [nucleoplasm]
(R-HSA-2997690)
0.556
3
UniProt:P02545 LMNA
3
LMNA(1-567)-p-RAF1(279-648) fusion [cytosol]
(R-HSA-6802537)
LMNA(1-567)-RAF1(279-648) fusion [cytosol]
(R-HSA-6802399)
LMNA(1-646) [nuclear envelope]
(R-HSA-535479)
0.556
3
UniProt:P14136 GFAP
3
p-GFAP [lysosomal membrane]
(R-HSA-9626054)
GFAP [lysosomal membrane]
(R-HSA-9625195)
GFAP [cytosol]
(R-HSA-1253311)
0.556
3
UniProt:Q6DKK2 TTC19
1
TTC19 [mitochondrial inner membrane]
(R-HSA-9906047)
0.527
2
UniProt:Q9NYA4 MTMR4
2
MTMR4 [cytosol]
(R-HSA-1604658)
MTMR4 [early endosome membrane]
(R-HSA-2187404)
0.527
2
UniProt:Q8WYA0 IFT81
2
IFT81 [cilium]
(R-HSA-5617769)
IFT81 [ciliary tip]
(R-HSA-5625369)
0.527
2
UniProt:Q9NZ53 PODXL2
2
OSulf-Y97,118-PODXL2 [Golgi lumen]
(R-HSA-8954273)
PODXL2 [Golgi lumen]
(R-HSA-8954248)
0.527
2
UniProt:Q96LB3 IFT74
2
IFT74 [ciliary tip]
(R-HSA-5625364)
IFT74 [cilium]
(R-HSA-5617616)
0.527
2
UniProt:P46939 UTRN
1
UTRN [cytosol]
(R-HSA-5216039)
0.527
2
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