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RAC2:GTP [phagocytic vesicle membrane]
Stable Identifier
R-HSA-5668609
Type
Complex
Species
Homo sapiens
Compartment
phagocytic vesicle membrane
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
ROS and RNS production in phagocytes (Homo sapiens)
NOX2 generates superoxide anion from oxygen (Homo sapiens)
NOX2 complex:RAC2:GTP [phagocytic vesicle membrane] (Homo sapiens)
RAC2:GTP [phagocytic vesicle membrane] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase Effectors (Homo sapiens)
RHO GTPases Activate NADPH Oxidases (Homo sapiens)
Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP (Homo sapiens)
NOX2 complex:RAC2:GTP [phagocytic vesicle membrane] (Homo sapiens)
RAC2:GTP [phagocytic vesicle membrane] (Homo sapiens)
NOX2 complex:S100A8:S100A9:Ca2+ [phagocytic vesicle membrane] (Homo sapiens)
NOX2 complex:RAC2:GTP [phagocytic vesicle membrane] (Homo sapiens)
RAC2:GTP [phagocytic vesicle membrane] (Homo sapiens)
RAC2:GTP binds NOX2 complex (Homo sapiens)
NOX2 complex:RAC2:GTP [phagocytic vesicle membrane] (Homo sapiens)
RAC2:GTP [phagocytic vesicle membrane] (Homo sapiens)
RAC2:GTP [phagocytic vesicle membrane] (Homo sapiens)
S100A8:S100A9:AA:Ca(2+) binds NOX2 complex (Homo sapiens)
NOX2 complex:RAC2:GTP [phagocytic vesicle membrane] (Homo sapiens)
RAC2:GTP [phagocytic vesicle membrane] (Homo sapiens)
NOX2 complex:S100A8:S100A9:Ca2+ [phagocytic vesicle membrane] (Homo sapiens)
NOX2 complex:RAC2:GTP [phagocytic vesicle membrane] (Homo sapiens)
RAC2:GTP [phagocytic vesicle membrane] (Homo sapiens)
RHO GTPase cycle (Homo sapiens)
RAC2 GTPase cycle (Homo sapiens)
RAC2 binds effectors at the phagocytic vesicle membrane (Homo sapiens)
RAC2:GTP [phagocytic vesicle membrane] (Homo sapiens)
RAC2:GTP:RAC2 phagosome effectors [phagocytic vesicle membrane] (Homo sapiens)
RAC2:GTP [phagocytic vesicle membrane] (Homo sapiens)
RAC2 translocates to the phagocytic vesicle membrane (Homo sapiens)
RAC2:GTP [phagocytic vesicle membrane] (Homo sapiens)
Participants
components
GTP [cytosol]
RAC2 [phagocytic vesicle membrane]
(Homo sapiens)
Participates
as an output of
RAC2 translocates to the phagocytic vesicle membrane (Homo sapiens)
as a component of
RAC2:GTP:RAC2 phagosome effectors [phagocytic vesicle membrane] (Homo sapiens)
NOX2 complex:RAC2:GTP [phagocytic vesicle membrane] (Homo sapiens)
as an input of
RAC2 binds effectors at the phagocytic vesicle membrane (Homo sapiens)
RAC2:GTP binds NOX2 complex (Homo sapiens)
Inferred To
RAC2:GTP [phagocytic vesicle membrane]
(Bos taurus)
RAC2:GTP [phagocytic vesicle membrane]
(Caenorhabditis elegans)
RAC2:GTP [phagocytic vesicle membrane]
(Canis familiaris)
RAC2:GTP [phagocytic vesicle membrane]
(Danio rerio)
RAC2:GTP [phagocytic vesicle membrane]
(Dictyostelium discoideum)
RAC2:GTP [phagocytic vesicle membrane]
(Drosophila melanogaster)
RAC2:GTP [phagocytic vesicle membrane]
(Gallus gallus)
RAC2:GTP [phagocytic vesicle membrane]
(Mus musculus)
RAC2:GTP [phagocytic vesicle membrane]
(Rattus norvegicus)
RAC2:GTP [phagocytic vesicle membrane]
(Sus scrofa)
RAC2:GTP [phagocytic vesicle membrane]
(Xenopus tropicalis)
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