MYLK (MLCK) phosphorylates MRLCs of the non-muscle myosin II complex

Stable Identifier
R-HSA-5668978
Type
Reaction
Species
Homo sapiens
Compartment
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MYLK (MLCK) is a Ca2+/calmodulin-dependent myosin light chain kinase that phosphorylates myosin regulatory light chains (MRLC) MYL9 and MYL12B at threonine T19 and serine S20 (also labeled in literature as T18 and S19) (Ikebe and Hartshorne 1985, Ikebe et al. 1986).

Literature References
Participants
Participates
Catalyst Activity

myosin light chain kinase activity of MYLK:Ca2+:CALM1 [cytosol]

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