Reactome | DPY30 [nucleoplasm]

DPY30 [nucleoplasm]

Stable Identifier

R-HSA-5669104

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Protein dpy-30 homolog, DPY30_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9C005 DPY30

Gene Names

DPY30

Chain

chain:1-99

Reference Genes

BioGPS Gene:84661 DPY30

COSMIC (genes):DPY30 DPY30

CTD Gene:84661 DPY30

dbSNP Gene:84661 DPY30

ENSEMBL:ENSG00000162961 DPY30

HGNC:24590 DPY30

KEGG Gene (Homo sapiens):84661 DPY30

Monarch:84661 DPY30

NCBI Gene:84661 DPY30

OMIM:612032 DPY30

UCSC:Q9C005 DPY30

Reference Transcript

Other Identifiers

0006860082

11744777_s_at

11757820_a_at

16896279

224129_s_at

2547390

2547391

2547392

2547393

2547395

2547400

2547402

2547403

2547404

2547405

2547417

3449952

50305_at

8051387

84661

A_23_P5389

GE62591

GO:0000781

GO:0002376

GO:0003674

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0005694

GO:0005737

GO:0005794

GO:0005802

GO:0006325

GO:0006348

GO:0006464

GO:0006810

GO:0008150

GO:0009058

GO:0016192

GO:0016197

GO:0030154

GO:0032991

GO:0034641

GO:0035097

GO:0042802

GO:0042803

GO:0043226

GO:0044666

GO:0045652

GO:0048188

GO:0048856

GO:0051276

GO:0051568

HMNXSV003017838

ILMN_2131880

ILMN_2131882

PH_hs_0027433

TC02005024.hg

g12655885_3p_a_at

Participates

as a component of

Core MLL complex [nucleoplasm] (Homo sapiens)

Inferred To

DPY30 [nucleoplasm] (Bos taurus)

DPY30 [nucleoplasm] (Canis familiaris)

DPY30 [nucleoplasm] (Gallus gallus)

DPY30 [nucleoplasm] (Sus scrofa)

Ghost homologue of DPY30 [nucleoplasm] (Dictyostelium discoideum)

Ghost homologue of DPY30 [nucleoplasm] (Saccharomyces cerevisiae)

Ghost homologue of DPY30 [nucleoplasm] (Xenopus tropicalis)

Dpy-30L1 [nucleoplasm] (Drosophila melanogaster)

Dpy30 [nucleoplasm] (Mus musculus)

Dpy30 [nucleoplasm] (Rattus norvegicus)

dpy-30 [nucleoplasm] (Caenorhabditis elegans)

dpy30 [nucleoplasm] (Danio rerio)

Cross References

RefSeq

NP_001308138.1, NP_115963.1

OpenTargets

ENSG00000162961

GeneCards

Q9C005

HPA

ENSG00000162961-DPY30

Ensembl

ENST00000295066, ENST00000342166, ENSG00000162961, ENSP00000295066, ENSP00000345837

PRO

Q9C005

Pharos - Targets

Q9C005

PDB

4RTA, 4RT4, 6PWV, 3G36, 6E2H, 4RIQ

Interactors (8)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9UBL3 ASH2L	1	ASH2L [nucleoplasm] (R-HSA-1629834)	0.965	22
UniProt:P61964 WDR5	1	WDR5 [nucleoplasm] (R-HSA-1629838)	0.812	8
UniProt:O00487 PSMD14	5	PSMD14 [secretory granule lumen] (R-HSA-6800926) PSMD14 [extracellular region] (R-HSA-6806511) PSMD14 [ficolin-1-rich granule lumen] (R-HSA-6800419) PSMD14 [nucleoplasm] (R-HSA-174329) PSMD14 [cytosol] (R-HSA-68722)	0.718	6
UniProt:Q15291 RBBP5	1	RBBP5 [nucleoplasm] (R-HSA-1629836)	0.69	4
UniProt:Q9P0U4 CXXC1	1	CXXC1 [nucleoplasm] (R-HSA-535610)	0.643	4
UniProt:Q68CJ9 CREB3L3	10	CREB3L3 [endoplasmic reticulum membrane] (R-HSA-6784669) CREB3L3 [Golgi membrane] (R-HSA-8874144) CREB3L3(365-461) [Golgi membrane] (R-HSA-8874130) CREB3L3(1-364) [Golgi membrane] (R-HSA-8874158) CREB3L3(1-323) [cytosol] (R-HSA-8874214) CREB3L3(1-323) [nucleoplasm] (R-HSA-8874217) CREB3L3(324-364) [Golgi membrane] (R-HSA-8874183) CREB3L3(1-?) [nucleoplasm] (R-HSA-6784629) CREB3L3(1-?) [cytosol] (R-HSA-6784654) CREB3L3(?-461) [endoplasmic reticulum membrane] (R-HSA-6784710)	0.556	3
UniProt:Q09028 RBBP4	1	RBBP4 [nucleoplasm] (R-HSA-212223)	0.527	2
UniProt:Q6ZW49 PAXIP1	1	PAXIP1 [nucleoplasm] (R-HSA-5619395)	0.527	2

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