NF2 [plasma membrane]

Stable Identifier
R-HSA-5669168
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Merlin, Moesin-ezrin-radixin-like protein, Neurofibromin-2, Schwannomerlin, Schwannomin, SCH
Locations in the PathwayBrowser for interactor UniProt:Q6ZNE9 RUFY4
Expand all
External Reference Information
External Reference
UniProt:P35240 NF2
Gene Names
NF2, SCH
Chain
chain:1-595
Reference Genes
BioGPS Gene:4771 NF2
COSMIC (genes):NF2 NF2
CTD Gene:4771 NF2
dbSNP Gene:4771 NF2
ENSEMBL:ENSG00000186575 NF2
ENSEMBL_homo_sapiens_GENE:ENSG00000186575.19 NF2
HGNC:7773 NF2
KEGG Gene (Homo sapiens):4771 NF2
Monarch:4771 NF2
NCBI Gene:4771 NF2
OMIM:607379 NF2
UCSC:P35240 NF2
Reference Transcript
Other Identifiers
11719746_a_at
11719747_a_at
11733352_a_at
11735884_at
11742197_a_at
11742198_x_at
11753857_x_at
16928824
204991_PM_s_at
204991_s_at
210767_PM_at
210767_at
211017_PM_s_at
211017_s_at
211091_PM_s_at
211091_s_at
211092_PM_s_at
211092_s_at
217150_PM_s_at
217150_s_at
218915_PM_at
218915_at
238618_PM_at
238618_at
38007_at
3942063
3942064
3942065
3942066
3942067
3942071
3942073
3942075
3942077
3942078
3942079
3942080
3942081
3942083
3942084
3942085
3942086
3942087
3942088
3942089
3942090
3942092
3942095
3942096
3942097
3942098
3942099
3942102
3942103
3942104
3942105
4771
53097_at
8072242
A_14_P115280
A_14_P131295
A_23_P251051
A_24_P168726
GE62153
GO:0000165
GO:0001707
GO:0001726
GO:0001953
GO:0003779
GO:0005178
GO:0005515
GO:0005634
GO:0005730
GO:0005737
GO:0005768
GO:0005769
GO:0005829
GO:0005856
GO:0005886
GO:0005912
GO:0007010
GO:0007155
GO:0007398
GO:0007420
GO:0008092
GO:0008285
GO:0008360
GO:0010626
GO:0012501
GO:0014010
GO:0014013
GO:0016020
GO:0016192
GO:0021766
GO:0022408
GO:0023052
GO:0030027
GO:0030036
GO:0030154
GO:0030175
GO:0030336
GO:0030864
GO:0031410
GO:0031527
GO:0031647
GO:0032154
GO:0032587
GO:0033687
GO:0033689
GO:0034330
GO:0035330
GO:0036211
GO:0042127
GO:0042475
GO:0042532
GO:0042981
GO:0042995
GO:0043005
GO:0043226
GO:0043409
GO:0044297
GO:0045177
GO:0045216
GO:0045597
GO:0046426
GO:0048471
GO:0048856
GO:0048870
GO:0050767
GO:0051496
GO:0051726
GO:0070306
GO:0072091
GO:1900180
GO:1902115
GO:1902966
GO:2000177
GO:2000643
HMNXSV003025821
HMNXSV003045132
Hs.202718.0.S1_3p_s_at
Hs.303179.0.S1_3p_at
Hs.303179.0.S1_3p_x_at
ILMN_1671267
ILMN_1676721
ILMN_1747580
ILMN_2412244
L11353_at
PH_hs_0000111
TC22000199.hg
TC22001059.hg
g13111888_3p_at
g4557794_3p_at
g5730863_3p_a_at
g5730865_3p_a_at
g5730867_3p_x_at
g9994194_3p_at
Participates
as a component of
as an input of
This entity regulates
Negatively
Inferred To
NF2 [plasma membrane] (Bos taurus)
NF2 [plasma membrane] (Canis familiaris)
NF2 [plasma membrane] (Gallus gallus)
NF2 [plasma membrane] (Sus scrofa)
NF2 [plasma membrane] (Xenopus tropicalis)
nfm-1 [plasma membrane] (Caenorhabditis elegans)
Mer [plasma membrane] (Drosophila melanogaster)
Nf2 [plasma membrane] (Mus musculus)
Nf2 [plasma membrane] (Rattus norvegicus)
Cross References
RefSeq
OpenTargets
HPA
GeneCards
Ensembl
PRO
Pharos - Targets
Orphanet
PDB
Interactors (43)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q4VCS5 AMOT      0.882 10
 UniProt:Q8IY63 AMOTL1  1 0.725 5
 UniProt:O14964 HGS  2 0.7 7
 UniProt:O60341 KDM1A  1 0.666 4
 UniProt:Q16584 MAP3K11  1 0.645 4
 UniProt:Q9Y2J4 AMOTL2  1 0.643 3
 UniProt:Q9BZE4 GTPB4      0.61 9
 UniProt:Q4VCS5-2 AMOT  1 0.591 6
 UniProt:Q9H204 MED28  1 0.581 4
 UniProt:O76041 NEBL      0.556 3
 UniProt:Q5TAQ9-2 Q5TAQ92      0.556 3
 UniProt:Q99598 TSNAX  1 0.556 3
 UniProt:Q96KP6 TNIP3  1 0.556 3
 UniProt:Q8NEZ2 VPS37A  1 0.556 3
 UniProt:Q8WXF7 ATLA1      0.556 3
 UniProt:Q86WT6-2 TRIM69      0.556 3
 UniProt:Q5VYS8-5 TUT7      0.556 3
 UniProt:Q8WWB5 PIHD2      0.556 3
 UniProt:Q9C0F3 ZNF436  1 0.556 3
 UniProt:Q6ZR37 PKHG7      0.556 3
 UniProt:P17024 ZNF20  1 0.556 3
 UniProt:Q6ZNH5 ZN497      0.556 3
 UniProt:Q14525 KRT33B  1 0.556 3
 UniProt:Q15776 ZKSCAN8  1 0.556 3
 UniProt:Q6ZNE9 RUFY4      0.556 3
 UniProt:P54274-2 TERF1      0.556 3
 UniProt:Q9BY12-3 Q9BY123      0.556 3
 UniProt:Q6X4W1-6 NSMF      0.556 3
 UniProt:Q8TBB1 LNX1  1 0.556 3
 UniProt:O95835 LATS1  2 0.556 4
 UniProt:Q7Z3I7 ZN572      0.556 3
 UniProt:Q8IZU1 FAM9A      0.556 3
 UniProt:Q6H8Q1-8 ABLIM2      0.556 3
 UniProt:Q9UNS2 COPS3  2 0.556 3
 UniProt:O75530-2 EED      0.556 3
 UniProt:Q13573 SNW1  1 0.556 3
 UniProt:O75925 PIAS1  1 0.556 3
 UniProt:Q9UNE7 STUB1  1 0.556 3
 UniProt:P46937 YAP1  8 0.527 2
 UniProt:Q10728 Ppp1r12a  5 0.524 2
 UniProt:P0DPB4 SCHI1      0.508 2
 UniProt:Q4VCS5-1 AMOT  1 0.499 2
 UniProt:Q8NI35 PATJ  1 0.499 2
Cite Us!