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ATG4B [cytosol]
Stable Identifier
R-HSA-5671858
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Cysteine protease ATG4B ecNumber3.4.22.-/ecNumber, ATG4B_HUMAN
Locations in the PathwayBrowser
Expand all
Autophagy (Homo sapiens)
Macroautophagy (Homo sapiens)
LC3 de-lipidation by ATG4 (Homo sapiens)
ATG4 [cytosol] (Homo sapiens)
ATG4B [cytosol] (Homo sapiens)
LC3 is cleaved by ATG4 (Homo sapiens)
ATG4 [cytosol] (Homo sapiens)
ATG4B [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9Y4P1 ATG4B
Gene Names
ATG4B, APG4B, AUTL1, KIAA0943
Chain
chain:1-393
Reference Genes
BioGPS Gene:23192 ATG4B
COSMIC (genes):ATG4B ATG4B
CTD Gene:23192 ATG4B
dbSNP Gene:23192 ATG4B
ENSEMBL:ENSG00000168397 ATG4B
HGNC:20790 ATG4B
KEGG:hsa:23192 ATG4B
Monarch:23192 ATG4B
NCBI Gene:23192 ATG4B
OMIM:611338 ATG4B
UCSC:Q9Y4P1 ATG4B
Reference Transcript
RefSeq:NM_178326.3 ATG4B
RefSeq:NM_013325.4 ATG4B
Other Identifiers
11734680_a_at
11734681_a_at
11744687_x_at
11750446_x_at
11754092_x_at
11757568_x_at
16893540
204902_3p_s_at
204902_PM_s_at
204902_s_at
204903_3p_x_at
204903_PM_x_at
204903_x_at
212280_3p_x_at
212280_PM_x_at
212280_x_at
23192
2536678
2536679
2536683
2536684
2536685
2536686
2536687
2536688
2536689
2536690
2536691
2536692
2536693
2536695
2536696
2536697
2536699
2536700
2536701
2536702
2536703
2536704
2536706
2536708
2536709
2536710
2536711
2536712
2536713
2536714
2536715
2536716
2536717
2536718
2536719
2536720
37041_at
4046360
4046361
4046367
4046368
4046369
4046370
4046371
4046372
4046373
4046374
4046375
4046376
4046377
4046378
4046381
4046382
4046383
4046386
4046387
4046388
4046389
4046390
4046391
4046392
4046394
4046396
4046397
4046398
4046399
4046400
4046401
4046402
4046403
4046404
4046405
4046406
4046407
4046408
4046409
4046410
4046411
4046412
8049888
8077211
A_23_P9903
A_24_P182764
A_33_P3335137
GE81820
GO:0000045
GO:0000421
GO:0000423
GO:0003824
GO:0004175
GO:0004197
GO:0005515
GO:0005737
GO:0005739
GO:0005773
GO:0005776
GO:0005783
GO:0005829
GO:0006508
GO:0006914
GO:0008233
GO:0008234
GO:0015031
GO:0016236
GO:0016237
GO:0016485
GO:0016787
GO:0019786
GO:0031173
GO:0031410
GO:0034497
GO:0034727
GO:0035973
GO:0048856
GO:0051697
GO:0097110
GO:0140096
HMNXSV003005124
Hs.272586.1.S1_3p_a_at
ILMN_1714050
ILMN_2411915
PH_hs_0023466
TC02001483.hg
g10835257_3p_a_at
g10835257_3p_s_at
g5262635_3p_a_at
g5262635_3p_x_at
Participates
as a member of
ATG4 [cytosol] (Homo sapiens)
Inferred To
Atg4b [cytosol]
(Mus musculus)
Atg4b [cytosol]
(Rattus norvegicus)
ATG4B [cytosol]
(Bos taurus)
ATG4B [cytosol]
(Canis familiaris)
ATG4B [cytosol]
(Dictyostelium discoideum)
ATG4B [cytosol]
(Gallus gallus)
ATG4B [cytosol]
(Plasmodium falciparum)
ATG4B [cytosol]
(Sus scrofa)
atg-4.1 [cytosol]
(Caenorhabditis elegans)
atg4b [cytosol]
(Danio rerio)
atg4b [cytosol]
(Xenopus tropicalis)
ATG4 [cytosol]
(Saccharomyces cerevisiae)
atg4 [cytosol]
(Schizosaccharomyces pombe)
Atg4a [cytosol]
(Drosophila melanogaster)
Cross References
RefSeq
NP_847896.1
,
NP_037457.3
Guide to Pharmacology - Targets
2329
ENSEMBL
ENSG00000168397
,
ENSP00000384259
,
ENSP00000383964
,
ENST00000405546
,
ENST00000402096
,
ENST00000404914
,
ENSP00000384661
OpenTargets
ENSG00000168397
GeneCards
ATG4B
HPA
ENSG00000168397-ATG4B
PRO
Q9Y4P1
Pharos - Targets
Q9Y4P1
GlyGen
Q9Y4P1
PDB
2Z0E
,
2ZZP
,
2CY7
,
5LXI
,
2D1I
,
5LXH
,
2Z0D
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9GZQ8 MAP1LC3B
4
MAP1LC3B [cytosol]
(R-HSA-5205651)
MAP1LC3B(2-121) [cytosol]
(R-HSA-5682674)
MAP1LC3B [autophagosome membrane]
(R-HSA-5683641)
MAP1LC3B [extracellular exosome]
(R-HSA-9959986)
0.952
15
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