Reactome | RAF/MAPK scaffolds [cytosol]

RAF/MAPK scaffolds [cytosol]

Stable Identifier

R-HSA-5672717

Type

Set [CandidateSet]

Species

Homo sapiens

Compartment

cytosol, plasma membrane

Locations in the PathwayBrowser

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Participants

members

p-S311 KSR1:MARK3 [cytosol] (Homo sapiens)

candidates

Participates

as a component of

p-BRAF/RAF fusion dimers:MAP2Ks:MAPKs:scaffold proteins [cytosol] (Homo sapiens)
p-BRAF/RAF fusion dimers:p-2S MAP2Ks:p-T,Y MAPKs:scaffold proteins [cytosol] (Homo sapiens)
p-BRAF/RAF fusion dimers:p-2S MAP2Ks:MAPKs:scaffold proteins [cytosol] (Homo sapiens)
activated RAF1 mutant:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Homo sapiens)
activated RAF1 mutant:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Homo sapiens)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Homo sapiens)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Homo sapiens)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Homo sapiens)
mutant RAS:GTP:p-RAF:p-2S MAP2Ks:p-T,Y MAPKs:scaffold proteins [plasma membrane] (Homo sapiens)
mutant RAS:GTP:p-RAF:p-2S MAP2Ks:MAPKs:scaffold proteins [plasma membrane] (Homo sapiens)
mutant RAS:GTP:p-RAF:MAP2Ks:MAPKs:scaffold proteins [plasma membrane] (Homo sapiens)
high kinase activity BRAF mutants:scaffold:MAP2K:MAPK complex [cytosol] (Homo sapiens)
high kinase activity BRAF mutants:scaffold:p-2S MAP2K:MAPK complex [cytosol] (Homo sapiens)
high kinase activity BRAF mutants:scaffold:p-2S MAP2K:p-T,Y MAPK complex [cytosol] (Homo sapiens)
RAS:GTP:moderate kinase activity p-RAF:MAP2Ks:MAPKs:scaffold proteins [plasma membrane] (Homo sapiens)
RAS:GTP:moderate kinase activity p-RAF:p-2S MAP2Ks:MAPKs:scaffold proteins [plasma membrane] (Homo sapiens)
RAS:GTP:moderate kinase activity p-RAF:p-2S MAP2Ks:p-T,Y MAPKs:scaffold proteins [plasma membrane] (Homo sapiens)
RAS:GTP: inactive p-RAF:p-2S MAP2Ks:MAPKs:scaffold proteins [plasma membrane] (Homo sapiens)
RAS:GTP:inactive p-RAF:p-2S MAP2Ks:p-T,Y MAPKs:scaffold proteins [plasma membrane] (Homo sapiens)
RAS:GTP:inactive p-RAF:MAP2Ks:MAPKs:scaffold proteins [plasma membrane] (Homo sapiens)
activated RAF1 mutant:scaffold:MAP2K:MAPK complex [plasma membrane] (Homo sapiens)

as an input of

as an output of

Inferred To

RAF/MAPK scaffolds [cytosol] (Bos taurus)

RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)

RAF/MAPK scaffolds [cytosol] (Canis familiaris)

RAF/MAPK scaffolds [cytosol] (Drosophila melanogaster)

RAF/MAPK scaffolds [cytosol] (Gallus gallus)

RAF/MAPK scaffolds [cytosol] (Mus musculus)

RAF/MAPK scaffolds [cytosol] (Plasmodium falciparum)

RAF/MAPK scaffolds [cytosol] (Rattus norvegicus)

RAF/MAPK scaffolds [cytosol] (Sus scrofa)

RAF/MAPK scaffolds [cytosol] (Xenopus tropicalis)

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