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MTORC1:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane]
Stable Identifier
R-HSA-5672812
Type
Complex
Species
Homo sapiens
Compartment
lysosomal membrane
Synonyms
Ragulator:Rag:GNP heterodimers:mTORC1:RHEB:GTP
Locations in the PathwayBrowser
Expand all
Autophagy (Homo sapiens)
Macroautophagy (Homo sapiens)
Active MTORC1 binds the ULK1 complex (Homo sapiens)
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Homo sapiens)
MTORC1:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Homo sapiens)
MTORC1:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Homo sapiens)
Active MTORC1 phosphorylates ULK1 (Homo sapiens)
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Homo sapiens)
MTORC1:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Homo sapiens)
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Homo sapiens)
MTORC1:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Homo sapiens)
Rheb in the MTORC1 complex hydrolyses GTP (Homo sapiens)
MTORC1:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Homo sapiens)
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Homo sapiens)
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Homo sapiens)
MTORC1:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Homo sapiens)
Signal Transduction (Homo sapiens)
Intracellular signaling by second messengers (Homo sapiens)
PIP3 activates AKT signaling (Homo sapiens)
PTEN Regulation (Homo sapiens)
Regulation of PTEN gene transcription (Homo sapiens)
MAF1 translocates to the nucleus (Homo sapiens)
MTORC1:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Homo sapiens)
mTORC1 phosphorylates MAF1 (Homo sapiens)
MTORC1:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Homo sapiens)
Participants
components
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane]
(Homo sapiens)
RHEB:GTP [lysosomal membrane]
(Homo sapiens)
Participates
as an input of
Rheb in the MTORC1 complex hydrolyses GTP (Homo sapiens)
Active MTORC1 binds the ULK1 complex (Homo sapiens)
as a component of
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Homo sapiens)
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Homo sapiens)
This entity regulates
Negatively
MAF1 translocates to the nucleus
(Homo sapiens)
Inferred To
Active mTORC1 complex [lysosomal membrane]
(Bos taurus)
Active mTORC1 complex [lysosomal membrane]
(Caenorhabditis elegans)
Active mTORC1 complex [lysosomal membrane]
(Canis familiaris)
Active mTORC1 complex [lysosomal membrane]
(Danio rerio)
Active mTORC1 complex [lysosomal membrane]
(Dictyostelium discoideum)
Active mTORC1 complex [lysosomal membrane]
(Drosophila melanogaster)
Active mTORC1 complex [lysosomal membrane]
(Gallus gallus)
Active mTORC1 complex [lysosomal membrane]
(Mus musculus)
Active mTORC1 complex [lysosomal membrane]
(Rattus norvegicus)
Active mTORC1 complex [lysosomal membrane]
(Sus scrofa)
Active mTORC1 complex [lysosomal membrane]
(Xenopus tropicalis)
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