hyperphosphorylated BRAF [plasma membrane]

Stable Identifier
R-HSA-5675199
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
p-S151,T401,S446,T599,S602,S729,S750,T753 BRAF, BRAF, B-RAF
hyperphosphorylated BRAF [plasma membrane] icon
Locations in the PathwayBrowser for interactor UniProt:P36507 MAP2K2
External Reference Information
External Reference
Gene Names
BRAF, BRAF1, RAFB1
Chain
initiator methionine:, chain:2-766
Reference Transcript
Other Identifiers
11732491_s_at
1654_at
17063631
206044_PM_s_at
206044_s_at
3076364
3076365
3076366
3076367
3076368
3076370
3076372
3076374
3076375
3076380
3076381
3076382
3076383
3076384
3076386
3076388
3076392
3076393
3076396
3076399
3076414
3076416
3076439
3076440
3076441
3076442
3982166
3982173
40306_at
673
8143417
86199_r_at
A_23_P42935
GE58163
GE766137
GO:0000165
GO:0000166
GO:0001934
GO:0002318
GO:0002376
GO:0003824
GO:0004672
GO:0004674
GO:0004708
GO:0004709
GO:0005509
GO:0005515
GO:0005524
GO:0005634
GO:0005737
GO:0005739
GO:0005829
GO:0005886
GO:0005975
GO:0006468
GO:0007010
GO:0007155
GO:0007165
GO:0007173
GO:0008152
GO:0008542
GO:0009887
GO:0010628
GO:0010764
GO:0010828
GO:0012501
GO:0016020
GO:0016079
GO:0016192
GO:0016301
GO:0016310
GO:0016740
GO:0023052
GO:0030154
GO:0030878
GO:0031434
GO:0033077
GO:0033138
GO:0034446
GO:0035019
GO:0036211
GO:0042127
GO:0042802
GO:0043005
GO:0043066
GO:0043149
GO:0043226
GO:0043231
GO:0043367
GO:0043368
GO:0043369
GO:0043434
GO:0043524
GO:0044297
GO:0044877
GO:0045580
GO:0046632
GO:0046872
GO:0048538
GO:0048679
GO:0048680
GO:0048856
GO:0048870
GO:0050772
GO:0050852
GO:0050877
GO:0051496
GO:0051591
GO:0055085
GO:0060291
GO:0060323
GO:0060324
GO:0070371
GO:0070374
GO:0070413
GO:0071277
GO:0071466
GO:0072577
GO:0090150
GO:0097110
GO:0098793
GO:0106310
GO:0140096
GO:1900026
GO:1902531
GO:1990090
GO:2000301
GO:2000352
HMNXSV003020754
ILMN_1652472
M95712_at
PH_hs_0027912
TC07001927.hg
g4757867_3p_a_at
Participates
Other forms of this molecule
Inferred To
Modified Residues
Name
O-phospho-L-serine at 446
Coordinate
446
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 729
Coordinate
729
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-threonine at 599
Coordinate
599
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-serine at 602
Coordinate
602
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 151
Coordinate
151
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 750
Coordinate
750
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-threonine at 753
Coordinate
753
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-threonine at 401
Coordinate
401
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Cross References
RefSeq
ZINC - World Drugs
Guide to Pharmacology - Targets
OpenTargets
ZINC - FDA approved
ZINC - Substances
ZINC - Biogenic
ZINC target
PRO
ZINC - Investigational
ZINC - Metabolites
GeneCards
Pharos - Targets
Orphanet
ZINC - Predictions - Purchasable
HMDB Protein
Interactors (31)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q02750 MAP2K1  20 0.978 63
 UniProt:P04049 RAF1  20 0.966 72
 UniProt:P63104 YWHAZ  2 0.924 13
 UniProt:P61981 YWHAG  1 0.912 12
 UniProt:P31946 YWHAB  1 0.905 11
 UniProt:P01112 HRAS  20 0.904 8
 UniProt:P27348 YWHAQ  1 0.901 11
 UniProt:P15056 BRAF  20 0.9 13
 UniProt:P36507 MAP2K2  12 0.886 12
 UniProt:P62258 YWHAE  1 0.859 10
 UniProt:Q04917 YWHAH  1 0.848 11
 UniProt:P10398 ARAF  4 0.827 7
 UniProt:P01111 NRAS  20 0.806 6
 UniProt:P31947 SFN  1 0.713 5
 UniProt:P08238 HSP90AB1  6 0.669 4
 UniProt:Q16543 CDC37  1 0.643 6
 UniProt:P01116 KRAS  20 0.615 4
 UniProt:Q13233 MAP3K1  2 0.609 2
 UniProt:Q02156 PRKCE  2 0.589 3
 UniProt:P46940 IQGAP1  3 0.544 4
 UniProt:Q9UH62 ARMCX3  1 0.527 2
 UniProt:P07098 LIPF  1 0.527 2
 UniProt:Q15042 RAB3GAP1  2 0.527 2
 UniProt:Q8N122 RPTOR  3 0.527 2
 UniProt:P11021 HSPA5  6 0.527 3
 UniProt:P11142 HSPA8  10 0.527 2
 UniProt:Q9UIM3 FKBPL  1 0.527 2
 UniProt:P38646 HSPA9  6 0.527 2
 UniProt:Q14154 DELE1  3 0.527 2
 UniProt:Q61097  5 0.499 3
 UniProt:Q99N57  11 0.499 3
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