Reactome | DUSP10 [cytosol]

DUSP10 [cytosol]

Stable Identifier

R-HSA-5675334

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9Y6W6 DUSP10

Gene Names

DUSP10, MKP5

Chain

chain:1-482

Reference Genes

BioGPS Gene:11221 DUSP10

COSMIC (genes):DUSP10 DUSP10

CTD Gene:11221 DUSP10

dbSNP Gene:11221 DUSP10

ENSEMBL:ENSG00000143507 DUSP10

ENSEMBL_homo_sapiens_GENE:ENSG00000143507.18 DUSP10

HGNC:3065 DUSP10

KEGG Gene (Homo sapiens):11221 DUSP10

Monarch:11221 DUSP10

NCBI Gene:11221 DUSP10

OMIM:608867 DUSP10

UCSC:Q9Y6W6 DUSP10

Reference Transcript

RefSeq:NM_007207.5 DUSP10

Other Identifiers

11221

11729169_a_at

11729170_x_at

11731303_a_at

11751237_a_at

16699533

215501_PM_s_at

215501_s_at

221563_PM_at

221563_at

2457260

2457262

2457263

2457264

2457267

2457268

2457283

2457284

2457285

2457288

2457289

38555_at

56889_at

7924450

A_23_P51856

A_24_P182494

GE53677

GO:0002376

GO:0002819

GO:0003824

GO:0004721

GO:0004722

GO:0004725

GO:0005515

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0006470

GO:0006954

GO:0007155

GO:0008138

GO:0008330

GO:0008432

GO:0010033

GO:0010633

GO:0016311

GO:0016787

GO:0016791

GO:0017017

GO:0017018

GO:0023052

GO:0030154

GO:0030336

GO:0032496

GO:0032873

GO:0033549

GO:0033550

GO:0035970

GO:0036211

GO:0043226

GO:0043508

GO:0045088

GO:0045591

GO:0046329

GO:0048273

GO:0048709

GO:0048715

GO:0048856

GO:0048870

GO:0050680

GO:0051403

GO:0060266

GO:0070373

GO:0090335

GO:0098542

GO:0140096

GO:1903753

GO:1905042

GO:1990264

HMNXSV003046016

HMNXSV003052620

Hs.177534.0.S2_3p_at

Hs.177534.1.S1_3p_a_at

ILMN_1759175

ILMN_2401873

ILMN_2401878

PH_hs_0010548

TC01003847.hg

Participates

as a candidate of

cytosolic MAPK DUSPs [cytosol] (Homo sapiens)

Other forms of this molecule

DUSP10 [nucleoplasm]

Inferred To

dusp10 [cytosol] (Xenopus tropicalis)

DUSP10 [cytosol] (Bos taurus)

DUSP10 [cytosol] (Canis familiaris)

DUSP10 [cytosol] (Dictyostelium discoideum)

DUSP10 [cytosol] (Gallus gallus)

DUSP10 [cytosol] (Plasmodium falciparum)

DUSP10 [cytosol] (Sus scrofa)

mpl1 [cytosol] (Dictyostelium discoideum)

puc [cytosol] (Drosophila melanogaster)

mpl2 [cytosol] (Dictyostelium discoideum)

mpl3 [cytosol] (Dictyostelium discoideum)

Dusp10 [cytosol] (Mus musculus)

Dusp10 [cytosol] (Rattus norvegicus)

Homologues of DUSP10 [cytosol] (Dictyostelium discoideum)

Cross References

RefSeq

NP_009138.1

OpenTargets

ENSG00000143507

GeneCards

Q9Y6W6

HPA

ENSG00000143507-DUSP10

ZINC - Substances

DUS10_HUMAN

ZINC target

Q9Y6W6

Ensembl

ENSG00000143507, ENSP00000355866, ENST00000366899

PRO

Q9Y6W6

Pharos - Targets

Q9Y6W6

ZINC - Predictions - Purchasable

DUS10_HUMAN

HMDB Protein

HMDBP08903

PDB

7Y4E, 3TG1, 2OUD, 7U4R, 7UN4, 7Y4D, 6MC1, 7U4O, 7UMV, 7UN0, 7Y4C, 2OUC, 7UMU, 7Y4B, 1ZZW

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P06396 GSN	7	GSN(200-270) [extracellular region] (R-HSA-976940) GSN [secretory granule lumen] (R-HSA-6801486) GSN [extracellular region] (R-HSA-6806510) GSN [ficolin-1-rich granule lumen] (R-HSA-6801465) GSN(404-782) [cytosol] (R-HSA-350272) GSN(28-403) [cytosol] (R-HSA-201618) GSN [cytosol] (R-HSA-350275)	0.556	3
UniProt:Q14957 GRIN2C	3	GRIN2C [plasma membrane] (R-HSA-419560) p-Y-GRIN2C [plasma membrane] (R-HSA-9612189) GRIN2C [endoplasmic reticulum membrane] (R-HSA-9609761)	0.556	3
UniProt:P49639 HOXA1	1	HOXA1 [nucleoplasm] (R-HSA-5617464)	0.556	5