Reactome | DUSP5 [nucleoplasm]

DUSP5 [nucleoplasm]

Stable Identifier

R-HSA-5675342

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q16690 DUSP5

Gene Names

DUSP5, VH3

Chain

chain:1-384

Reference Genes

BioGPS Gene:1847 DUSP5

COSMIC (genes):DUSP5 DUSP5

CTD Gene:1847 DUSP5

dbSNP Gene:1847 DUSP5

ENSEMBL:ENSG00000138166 DUSP5

HGNC:3071 DUSP5

KEGG:hsa:1847 DUSP5

Monarch:1847 DUSP5

NCBI Gene:1847 DUSP5

OMIM:603069 DUSP5

UCSC:Q16690 DUSP5

Reference Transcript

RefSeq:NM_004419.3 DUSP5

Other Identifiers

11717863_a_at

16709128

1847

209457_PM_at

209457_at

3263755

3263756

3263757

3263758

3263759

3263760

3263764

3263768

3263772

3263773

3263774

529_at

7930413

A_14_P126507

A_23_P150018

GE58962

GO:0000165

GO:0001706

GO:0003824

GO:0004721

GO:0004722

GO:0004725

GO:0005515

GO:0005634

GO:0005654

GO:0005737

GO:0006470

GO:0008138

GO:0008330

GO:0016311

GO:0016787

GO:0016791

GO:0017017

GO:0017018

GO:0033550

GO:0035335

GO:0035970

GO:0043226

GO:0043409

GO:0070371

GO:0140096

HMNXSV003013839

ILMN_1656501

PH_hs_0030877

TC10000801.hg

U15932_at

g642012_3p_at

Participates

as a member of

nuclear MAPK DUSPs [nucleoplasm] (Homo sapiens)

Inferred To

mpl2 [nucleoplasm] (Dictyostelium discoideum)

mpl1 [nucleoplasm] (Dictyostelium discoideum)

DUSP5 [nucleoplasm] (Bos taurus)

DUSP5 [nucleoplasm] (Canis familiaris)

DUSP5 [nucleoplasm] (Dictyostelium discoideum)

DUSP5 [nucleoplasm] (Gallus gallus)

DUSP5 [nucleoplasm] (Plasmodium falciparum)

DUSP5 [nucleoplasm] (Sus scrofa)

dusp5 [nucleoplasm] (Danio rerio)

dusp5 [nucleoplasm] (Xenopus tropicalis)

Dusp5 [nucleoplasm] (Mus musculus)

Dusp5 [nucleoplasm] (Rattus norvegicus)

Homologues of DUSP5 [nucleoplasm] (Dictyostelium discoideum)

mpl3 [nucleoplasm] (Dictyostelium discoideum)

Cross References

RefSeq

NP_004410.3

ENSEMBL

ENST00000369583, ENSP00000358596

OpenTargets

ENSG00000138166

HPA

ENSG00000138166-DUSP5

PRO

Q16690

Pharos - Targets

Q16690

HMDB Protein

HMDBP08912

PDB

2G6Z

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P28482 MAPK1	18	p-T185,Y187-MAPK1 [nucleoplasm] (R-HSA-112354) p-T185,Y187-MAPK1 [cytosol] (R-HSA-109853) MAPK1 [cytosol] (R-HSA-59282) MAPK1 [nucleoplasm] (R-HSA-199960) p-T185-MAPK1 [cytosol] (R-HSA-9635773) p-T185,Y187 MAPK1 P58G [cytosol] (R-HSA-9652802) p-T185,Y187 MAPK1 E322A [cytosol] (R-HSA-9652794) p-T185,Y187 MAPK1 D321N [cytosol] (R-HSA-9652785) p-T185,Y187 MAPK1 D321V [cytosol] (R-HSA-9652791) p-T185,Y187 MAPK1 P58L [cytosol] (R-HSA-9652806) p-T185,Y187 MAPK1 S142L [cytosol] (R-HSA-9652808) p-T185,Y187 MAPK1 E81K [cytosol] (R-HSA-9652799) p-T185,Y187 MAPK1 E322K [cytosol] (R-HSA-9652175) p-T185,Y187 MAPK1 E322V [cytosol] (R-HSA-9652797) MAPK1 [azurophil granule lumen] (R-HSA-6799225) MAPK1 [extracellular region] (R-HSA-6806250) MAPK1 [ficolin-1-rich granule lumen] (R-HSA-6800964) MAPK1 [endoplasmic reticulum lumen] (R-HSA-9636293)	0.543	3

© 2025 Reactome

Cite Us!