K48pUb-BIRC2 [cytosol]

Stable Identifier
R-HSA-5675479
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
K48polyUB-BIRC, K48polyUb-cIAP2
K48pUb-BIRC2 [cytosol] icon
Locations in the PathwayBrowser
External Reference Information
External Reference
Gene Names
BIRC2, API1, MIHB, RNF48
Chain
chain:1-618
Other Identifiers
11717627_a_at
11717628_a_at
11744694_a_at
11750887_a_at
11757937_s_at
16730540
202076_PM_at
202076_at
329
3346585
3346586
3346587
3346588
3346589
3346590
3346593
3346594
3346595
3346596
3346597
3346598
3346599
3346601
3346604
3346605
3346607
3346608
3346609
3346610
3346611
3346612
3346613
3346614
3346615
3346616
36578_at
7943424
A_14_P124015
A_14_P129741
A_14_P131109
A_24_P115774
GE59117
GO:0000209
GO:0001666
GO:0001741
GO:0001890
GO:0002376
GO:0003713
GO:0003824
GO:0004842
GO:0005515
GO:0005634
GO:0005694
GO:0005737
GO:0005829
GO:0005886
GO:0006351
GO:0006355
GO:0006915
GO:0006954
GO:0007166
GO:0007249
GO:0008270
GO:0009898
GO:0010243
GO:0012501
GO:0014070
GO:0016740
GO:0023052
GO:0030154
GO:0030163
GO:0031398
GO:0032991
GO:0033209
GO:0034121
GO:0035631
GO:0036211
GO:0038061
GO:0039535
GO:0042127
GO:0042802
GO:0042981
GO:0043027
GO:0043066
GO:0043123
GO:0043130
GO:0043161
GO:0043226
GO:0044877
GO:0045088
GO:0045471
GO:0045595
GO:0045893
GO:0046872
GO:0048856
GO:0050727
GO:0051087
GO:0051591
GO:0051726
GO:0060544
GO:0060546
GO:0061630
GO:0065003
GO:0070266
GO:0070424
GO:0071356
GO:0098542
GO:0098770
GO:0098772
GO:0140096
GO:0140110
GO:1901222
GO:1902443
GO:1902523
GO:1902524
GO:1902527
GO:1902916
GO:2000116
GO:2000377
HMNXSV003027101
ILMN_1768194
ILMN_2182704
PH_hs_0015035
TC11000957.hg
U37547_at
g10880127_3p_at
Participates
Other forms of this molecule
Inferred To
Modified Residues
Name
ubiquitinylated lysine (K48polyUb [cytosol]) at unknown position
Modification
K48polyUb [cytosol]
PsiMod Name
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Cross References
Guide to Pharmacology - Targets
OpenTargets
ZINC - Substances
ZINC target
PRO
ZINC - Investigational
GeneCards
Pharos - Targets
ZINC - Predictions - Purchasable
Interactors (69)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q12933 TRAF2  5 0.951 19
 UniProt:P55211 CASP9  5 0.919 12
 UniProt:Q9NR28 DIABLO  2 0.825 8
 UniProt:Q96HA8 NTAQ1      0.801 8
 UniProt:Q96CA5 BIRC7  1 0.801 8
 UniProt:Q13077 TRAF1  3 0.798 8
 UniProt:P01375 TNF  5 0.788 5
 UniProt:Q9Y3E2 BOLA1      0.781 7
 UniProt:Q92844 TANK  2 0.725 5
 UniProt:Q96CN9 GCC1  1 0.718 6
 UniProt:P08949-2 NMB      0.718 6
 UniProt:Q8N3J5 PPM1K  2 0.718 6
 UniProt:Q9NQT4 EXOSC5  2 0.718 6
 UniProt:Q13546 RIPK1  20 0.697 5
 UniProt:P19438 TNFRSF1A  2 0.69 4
 UniProt:Q13490 BIRC2  5 0.667 4
 UniProt:Q9BZW7 TSG10      0.666 4
 UniProt:O43464 HTRA2  1 0.65 4
 UniProt:P55210 CASP7  5 0.641 3
 ChEBI:47924 N,N'-(HEXANE-1,6-DIYL)BIS(1-{(2S)-2-CYCLOHEXYL-2-[(N-METHYL-L-ALANYL)AMINO]ACETYL}-L-PROLYL-BETA-PHENYL-L-PHENYLALANINAMIDE)      0.618 4
 ChEBI:47922 METHYL 1-{(2S)-2-CYCLOHEXYL-2-[(N-METHYL-L-ALANYL)AMINO]ACETYL}-L-PROLYL-BETA-PHENYL-L-PHENYLALANINATE      0.618 6
 UniProt:P57078 RIPK4      0.602 3
 UniProt:Q9Y572 RIPK3  8 0.602 3
 UniProt:O43353 RIPK2  2 0.602 3
 UniProt:Q9UBU9 NXF1  2 0.556 3
 UniProt:P40325 HUA1      0.556 3
 UniProt:A0A087WZT3 A0A087WZT3      0.556 3
 UniProt:P32502  1 0.556 3
 UniProt:P51813 BMX  3 0.556 3
 UniProt:P08949 NMB  1 0.556 3
 UniProt:Q06455-2 RUNX1T1      0.556 3
 UniProt:P51451 BLK  2 0.556 3
 UniProt:O60341 KDM1A  1 0.556 3
 IntAct:EBI-25847655 CCSB      0.556 3
 UniProt:Q01976  1 0.556 3
 UniProt:P38339  2 0.556 3
 UniProt:Q3E793 BOL1      0.556 3
 UniProt:P40937 RFC5  1 0.556 3
 UniProt:Q8WXH2 JPH3      0.556 3
 UniProt:Q8TBB1 LNX1  1 0.556 3
 UniProt:Q9Y4C2-2 TCAF1      0.556 3
 UniProt:Q96CJ1 EAF2  1 0.556 3
 UniProt:P14136 GFAP  3 0.556 3
 UniProt:O75173 ADAMTS4  4 0.527 3
 UniProt:Q9NYW3 TAS2R7  1 0.527 2
 UniProt:Q9H0L4 CSTF2T  1 0.527 2
 UniProt:P19086 GNAZ  2 0.527 2
 UniProt:P00736 C1R  3 0.527 3
 UniProt:Q9Y240 CLC11      0.527 3
 UniProt:P36941 LTBR  1 0.527 3
 UniProt:P30048 PRDX3  1 0.527 2
 UniProt:Q5T6F0 DCA12      0.527 4
 UniProt:Q9BQK8 LPIN3  3 0.527 3
 UniProt:Q96EP0 RNF31  1 0.527 3
 UniProt:Q9NQ34 TMM9B      0.527 2
 UniProt:O75351 VPS4B  1 0.527 2
 UniProt:Q86SG7 LYG2      0.527 3
 UniProt:Q9Y6K9 IKBKG  12 0.527 3
 UniProt:Q13114 TRAF3  4 0.527 3
 UniProt:O75325 LRRN2      0.527 2
 UniProt:P58062 ISK7      0.527 2
 UniProt:Q14790 CASP8  8 0.527 2
 UniProt:P26842 CD27  1 0.527 2
 UniProt:P17677 GAP43  2 0.527 2
 UniProt:P21580 TNFAIP3  1 0.527 2
 UniProt:P98170 XIAP  3 0.527 3
 UniProt:P63000 RAC1  6 0.525 2
 UniProt:Q96FW1 OTUB1  2 0.499 3
 UniProt:Q9NP84 TNFRSF12A  1 0.499 2
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