LC3 is cleaved by ATG4

Stable Identifier
R-HSA-5681987
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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LC3 family proteins are processed by members of the ATG4 family, which remove a C-terminal residue to create an exposed C-terminal glycine (Kirisako et al. 2000, Tanida et al. 2004, Kabeya et al. 2004, Li et al. 2011). Processed LC3 proteins are sometimes referred to as LC3-I.

Literature References
Participants
Participates
Catalyst Activity

cysteine-type endopeptidase activity of ATG4 [cytosol]

Orthologous Events
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