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TIPIN [nucleoplasm]
Stable Identifier
R-HSA-5684983
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
TIMELESS-interacting protein
Locations in the PathwayBrowser
Expand all
DNA Repair (Homo sapiens)
DNA Double-Strand Break Repair (Homo sapiens)
Homology Directed Repair (Homo sapiens)
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) (Homo sapiens)
Processing of DNA double-strand break ends (Homo sapiens)
Activation of CHEK1 at resected DNA DSBs (Homo sapiens)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1:TIMELESS:TIPIN:p-T916,S945-CLSPN:CHEK1 [nucleoplasm] (Homo sapiens)
TIMELESS:TIPIN [nucleoplasm] (Homo sapiens)
TIPIN [nucleoplasm] (Homo sapiens)
TIMELESS:TIPIN [nucleoplasm] (Homo sapiens)
TIPIN [nucleoplasm] (Homo sapiens)
CHEK1 is recruited to resected DNA DSBs (Homo sapiens)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1:TIMELESS:TIPIN:p-T916,S945-CLSPN:CHEK1 [nucleoplasm] (Homo sapiens)
TIMELESS:TIPIN [nucleoplasm] (Homo sapiens)
TIPIN [nucleoplasm] (Homo sapiens)
TIMELESS:TIPIN [nucleoplasm] (Homo sapiens)
TIPIN [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9BVW5 TIPIN
Gene Names
TIPIN
Chain
chain:1-301
Reference Genes
BioGPS Gene:54962 TIPIN
COSMIC (genes):TIPIN TIPIN
CTD Gene:54962 TIPIN
dbSNP Gene:54962 TIPIN
ENSEMBL:ENSG00000075131 TIPIN
ENSEMBL_homo_sapiens_GENE:ENSG00000075131.10 TIPIN
HGNC:30750 TIPIN
KEGG Gene (Homo sapiens):54962 TIPIN
Monarch:54962 TIPIN
NCBI Gene:54962 TIPIN
OMIM:610716 TIPIN
UCSC:Q9BVW5 TIPIN
Reference Transcript
RefSeq:XM_005254521.2 TIPIN
RefSeq:XM_017022390.1 TIPIN
RefSeq:NM_017858.2 TIPIN
RefSeq:NM_001289986.1 TIPIN
RefSeq:XM_011521743.1 TIPIN
RefSeq:XM_006720594.3 TIPIN
RefSeq:XM_005254522.4 TIPIN
Other Identifiers
11727081_a_at
11761621_at
11761622_x_at
16810933
219258_PM_at
219258_at
3630100
3630101
3630102
3630103
3630106
3630108
3630109
3630110
3630111
3630112
3693513
4009309
4009312
43381_s_at
54962
64738_at
7989915
A_23_P99930
GE82236
GO:0000076
GO:0000077
GO:0000228
GO:0000278
GO:0000785
GO:0003677
GO:0005515
GO:0005634
GO:0005654
GO:0005694
GO:0005737
GO:0006260
GO:0006974
GO:0007049
GO:0008284
GO:0009411
GO:0023052
GO:0031297
GO:0031298
GO:0031573
GO:0033262
GO:0043111
GO:0043226
GO:0044770
GO:0051301
HMNXSV003001308
HMNXSV003014709
ILMN_1761939
PH_hs_0035946
TC15001576.hg
g8923484_3p_at
Participates
as a component of
TIMELESS:TIPIN [nucleoplasm] (Homo sapiens)
Inferred To
Tipin [nucleoplasm]
(Mus musculus)
Tipin [nucleoplasm]
(Rattus norvegicus)
CSM3 [nucleoplasm]
(Saccharomyces cerevisiae)
Homologues of TIPIN [nucleoplasm]
(Rattus norvegicus)
tipn-1 [nucleoplasm]
(Caenorhabditis elegans)
TIPIN [nucleoplasm]
(Bos taurus)
TIPIN [nucleoplasm]
(Canis familiaris)
TIPIN [nucleoplasm]
(Drosophila melanogaster)
TIPIN [nucleoplasm]
(Gallus gallus)
TIPIN [nucleoplasm]
(Sus scrofa)
swi3 [nucleoplasm]
(Schizosaccharomyces pombe)
Cross References
RefSeq
XP_016877879.1
,
XP_005254578.1
,
XP_005254579.1
,
XP_011520045.1
,
NP_060328.2
,
XP_006720657.1
,
NP_001276915.1
OpenTargets
ENSG00000075131
HPA
ENSG00000075131-TIPIN
GeneCards
Q9BVW5
Ensembl
ENST00000261881
,
ENSG00000075131
,
ENSP00000261881
PRO
Q9BVW5
Pharos - Targets
Q9BVW5
PDB
7PLO
,
7PFO
,
8B9D
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9BRX5 GINS3
1
GINS3 [nucleoplasm]
(R-HSA-5688046)
0.527
2
UniProt:Q9BRT9 GINS4
1
GINS4 [nucleoplasm]
(R-HSA-176963)
0.527
2
UniProt:Q14691 GINS1
1
GINS1 [nucleoplasm]
(R-HSA-176955)
0.527
2
UniProt:P33993 MCM7
1
MCM7 [nucleoplasm]
(R-HSA-68555)
0.527
2
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