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TRAPPC6A [cytosol]
Stable Identifier
R-HSA-5685733
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Asparagine N-linked glycosylation (Homo sapiens)
Transport to the Golgi and subsequent modification (Homo sapiens)
ER to Golgi Anterograde Transport (Homo sapiens)
COPII-mediated vesicle transport (Homo sapiens)
COPII coat binds TRAPPCII and RAB1:GDP (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC6A [cytosol] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC6A [cytosol] (Homo sapiens)
CSNK1D phosphorylates SEC23 (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC6A [cytosol] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC6A [cytosol] (Homo sapiens)
Nucleotide exchange on RAB1 (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC6A [cytosol] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC6A [cytosol] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC6A [cytosol] (Homo sapiens)
RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC6A [cytosol] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC6A [cytosol] (Homo sapiens)
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
ER to Golgi Anterograde Transport (Homo sapiens)
COPII-mediated vesicle transport (Homo sapiens)
COPII coat binds TRAPPCII and RAB1:GDP (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC6A [cytosol] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC6A [cytosol] (Homo sapiens)
CSNK1D phosphorylates SEC23 (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC6A [cytosol] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC6A [cytosol] (Homo sapiens)
Nucleotide exchange on RAB1 (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC6A [cytosol] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC6A [cytosol] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC6A [cytosol] (Homo sapiens)
RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC6A [cytosol] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC6A [cytosol] (Homo sapiens)
Rab regulation of trafficking (Homo sapiens)
RAB GEFs exchange GTP for GDP on RABs (Homo sapiens)
TRAPPC complexes exchange GTP for GDP on RAB1 (Homo sapiens)
TRAPPCs [cytosol] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC6A [cytosol] (Homo sapiens)
TRAPPCIII [cytosol] (Homo sapiens)
TRAPPC6A [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:O75865 TRAPPC6A
Gene Names
TRAPPC6A, HSPC289
Chain
chain:1-159
Reference Genes
BioGPS Gene:79090 TRAPPC6A
COSMIC (genes):TRAPPC6A TRAPPC6A
CTD Gene:79090 TRAPPC6A
dbSNP Gene:79090 TRAPPC6A
ENSEMBL:ENSG00000007255 TRAPPC6A
HGNC:23069 TRAPPC6A
KEGG:hsa:79090 TRAPPC6A
Monarch:79090 TRAPPC6A
NCBI Gene:79090 TRAPPC6A
OMIM:610396 TRAPPC6A
UCSC:O75865 TRAPPC6A
Reference Transcript
RefSeq:NM_001270893.1 TRAPPC6A
RefSeq:NM_001270891.1 TRAPPC6A
RefSeq:NM_001270892.1 TRAPPC6A
RefSeq:NM_024108.2 TRAPPC6A
Participates
as a component of
TRAPPCIII [cytosol] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
Inferred To
Trs33 [cytosol]
(Drosophila melanogaster)
trappc6bl [cytosol]
(Danio rerio)
Trappc6a [cytosol]
(Mus musculus)
Trappc6a [cytosol]
(Rattus norvegicus)
Ghost homologue of TRAPPC6A [cytosol]
(Gallus gallus)
TRAPPC6A [cytosol]
(Bos taurus)
TRAPPC6A [cytosol]
(Canis familiaris)
TRAPPC6A [cytosol]
(Dictyostelium discoideum)
TRAPPC6A [cytosol]
(Plasmodium falciparum)
TRAPPC6A [cytosol]
(Schizosaccharomyces pombe)
TRAPPC6A [cytosol]
(Sus scrofa)
trappc6a [cytosol]
(Xenopus tropicalis)
TRS33 [cytosol]
(Saccharomyces cerevisiae)
trpp-6 [cytosol]
(Caenorhabditis elegans)
Cross References
ENSEMBL
ENSG00000007255
,
ENSP00000468612
,
ENSP00000006275
,
ENSP00000468182
,
ENST00000006275
,
ENST00000592647
,
ENST00000585934
,
ENST00000588062
,
ENSP00000468363
OpenTargets
ENSG00000007255
GeneCards
TRAPPC6A
HPA
ENSG00000007255-TRAPPC6A
PRO
O75865
Pharos - Targets
O75865
PDB
2J3T
,
2C0J
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q96QF0 RAB3IP
1
RAB3IP [cytosol]
(R-HSA-5617610)
0.666
4
UniProt:P09022 Hoxa1
1
Hoxa1 [nucleoplasm]
(R-MMU-5617924)
0.57
3
UniProt:Q9Y296 TRAPPC4
2
TRAPPC4 [cytosol]
(R-HSA-5683764)
TRAPPC4 [plasma membrane]
(R-HSA-2682314)
0.544
2
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