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SPIDR [nucleoplasm]
Stable Identifier
R-HSA-5686408
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
DNA repair-scaffolding protein, KIAA0146
Locations in the PathwayBrowser for interactor UniProt:Q6NVH7 SWAP1
Expand all
DNA Repair (Homo sapiens)
DNA Double-Strand Break Repair (Homo sapiens)
Homology Directed Repair (Homo sapiens)
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) (Homo sapiens)
HDR through Homologous Recombination (HRR) (Homo sapiens)
Resolution of D-Loop Structures (Homo sapiens)
Resolution of D-loop Structures through Holliday Junction Intermediates (Homo sapiens)
FIGNL1 binds SPIDR (Homo sapiens)
SPIDR [nucleoplasm] (Homo sapiens)
SPIDR binds BLM:TOP3A:RMI1:RMI2 (Homo sapiens)
SPIDR [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q14159 SPIDR
Gene Names
SPIDR, KIAA0146
Chain
chain:1-915
Reference Genes
BioGPS Gene:23514 SPIDR
COSMIC (genes):SPIDR SPIDR
CTD Gene:23514 SPIDR
dbSNP Gene:23514 SPIDR
ENSEMBL:ENSG00000164808 SPIDR
ENSEMBL_homo_sapiens_GENE:ENSG00000164808.17 SPIDR
HGNC:28971 SPIDR
KEGG Gene (Homo sapiens):23514 SPIDR
Monarch:23514 SPIDR
NCBI Gene:23514 SPIDR
OMIM:615384 SPIDR
UCSC:Q14159 SPIDR
Reference Transcript
RefSeq:XM_017013271.1 SPIDR
RefSeq:NM_001282916.1 SPIDR
RefSeq:NM_001282919.1 SPIDR
RefSeq:NM_001080394.3 SPIDR
Other Identifiers
11718246_a_at
11746386_a_at
11746387_x_at
11746388_x_at
11746542_x_at
11747475_a_at
11747476_x_at
11747798_a_at
11749411_a_at
11750434_x_at
11754805_a_at
17068724
17082962
212523_PM_s_at
212523_s_at
23514
3096934
3096941
3096942
3096943
3096946
3096948
3096979
3096983
3096992
3097029
3097030
3097056
3097071
3097072
3097073
3097074
3097084
3097086
3097095
3097097
3097098
3097099
3097105
3097106
3097107
32561_at
4050009
4050011
4050013
4050015
4050017
42362_at
8146336
A_14_P123664
A_14_P200239
A_23_P327013
A_24_P143686
D63480_at
GO:0000228
GO:0000724
GO:0005515
GO:0005634
GO:0005654
GO:0005694
GO:0006281
GO:0006310
GO:0006974
GO:0010569
GO:0031334
GO:0043226
GO:0065003
GO:0070202
GO:0071479
GO:0072711
GO:0072757
GO:2000781
HMNXSV003010624
HMNXSV003035441
Hs.278634.0.A1_3p_a_at
ILMN_1887174
PH_hs_0033029
Participates
as an input of
FIGNL1 binds SPIDR (Homo sapiens)
SPIDR binds BLM:TOP3A:RMI1:RMI2 (Homo sapiens)
as a component of
FIRRM:FIGNL1:SPIDR [nucleoplasm] (Homo sapiens)
BLM:TOP3A:RMI1:RMI2:SPIDR [nucleoplasm] (Homo sapiens)
Inferred To
spidr [nucleoplasm]
(Xenopus tropicalis)
SPIDR [nucleoplasm]
(Bos taurus)
SPIDR [nucleoplasm]
(Gallus gallus)
SPIDR [nucleoplasm]
(Sus scrofa)
Spidr [nucleoplasm]
(Mus musculus)
Spidr [nucleoplasm]
(Rattus norvegicus)
Cross References
RefSeq
NP_001073863.1
,
NP_001269848.1
,
XP_016868760.1
,
NP_001269845.1
OpenTargets
ENSG00000164808
GeneCards
Q14159
HPA
ENSG00000164808-SPIDR
Ensembl
ENSP00000429487
,
ENSP00000297423
,
ENST00000541342
,
ENST00000297423
,
ENST00000518074
,
ENSP00000444061
,
ENSG00000164808
PRO
Q14159
Pharos - Targets
Q14159
Orphanet
25448
Interactors (9)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P54132 BLM
2
4SUMO2,3-BLM [nucleoplasm]
(R-HSA-4568883)
BLM [nucleoplasm]
(R-HSA-174881)
0.663
11
UniProt:Q19AV6 ZSWM7
0.661
8
UniProt:Q06609 RAD51
2
RAD51 [nucleoplasm]
(R-HSA-62637)
p-T309-RAD51 [nucleoplasm]
(R-HSA-5685231)
0.659
6
UniProt:Q6NVH7 SWAP1
0.632
7
UniProt:O15496 PLA2G10
1
PLA2G10 [extracellular region]
(R-HSA-1498793)
0.527
2
UniProt:Q6PIW4 FIGNL1
1
FIGNL1 [nucleoplasm]
(R-HSA-9853365)
0.488
3
UniProt:Q96E14 RMI2
1
RMI2 [nucleoplasm]
(R-HSA-5685951)
0.462
2
UniProt:Q13472 TOP3A
1
TOP3A [nucleoplasm]
(R-HSA-912452)
0.462
2
UniProt:Q9H9A7 RMI1
1
RMI1 [nucleoplasm]
(R-HSA-5685949)
0.462
2
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