p-S215 FOXO3 binds MIR34B and C gene

Stable Identifier
R-HSA-5687095
Type
Reaction [binding]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Phosphorylated FOXO3 binds to consensus sites in the promoter of MIR34B and C genes as assessed by ChIP, promoting expression of the microRNAs (Kress et al, 2011).
Literature References
PubMed ID Title Journal Year
21329882 The MK5/PRAK kinase and Myc form a negative feedback loop that is disrupted during colorectal tumorigenesis

Kress, TR, Eilers, M, Roepman, P, Bushell, M, Samans, B, Cannell, IG, Rosenwald, A, Gaestel, M, Burgering, BM, Brenkman, AB

Mol. Cell 2011
Participants
Participates
Authored
Reviewed
Created
Cite Us!