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DDX46 [nucleoplasm]
Stable Identifier
R-HSA-5688096
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Probable ATP-dependent RNA helicase DDX46 ecNumber3.6.4.13/ecNumber, DDX46_HUMAN, hPrp5
Locations in the PathwayBrowser
Expand all
Metabolism of RNA (Homo sapiens)
Processing of Capped Intron-Containing Pre-mRNA (Homo sapiens)
mRNA Splicing (Homo sapiens)
mRNA Splicing - Major Pathway (Homo sapiens)
Disassembly of the Intron Lariat Spliceosome (new) (Homo sapiens)
Intron Lariat Spliceosome (ILS) [nucleoplasm] (Homo sapiens)
U2 12S snRNP [nucleoplasm] (Homo sapiens)
DDX46 [nucleoplasm] (Homo sapiens)
U2 12S snRNP [nucleoplasm] (Homo sapiens)
DDX46 [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal A complex (Homo sapiens)
DDX46 [nucleoplasm] (Homo sapiens)
Spliceosomal A complex [nucleoplasm] (Homo sapiens)
U2 snRNP [nucleoplasm] (Homo sapiens)
DDX46 [nucleoplasm] (Homo sapiens)
U2 snRNP [nucleoplasm] (Homo sapiens)
DDX46 [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal B complex (Homo sapiens)
Spliceosomal B complex [nucleoplasm] (Homo sapiens)
U2 snRNP [nucleoplasm] (Homo sapiens)
DDX46 [nucleoplasm] (Homo sapiens)
Spliceosomal Pre-B complex [nucleoplasm] (Homo sapiens)
U2 snRNP [nucleoplasm] (Homo sapiens)
DDX46 [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal B* complex (Homo sapiens)
Spliceosomal B* complex [nucleoplasm] (Homo sapiens)
U2 12S snRNP [nucleoplasm] (Homo sapiens)
DDX46 [nucleoplasm] (Homo sapiens)
Spliceosomal Bact complex [nucleoplasm] (Homo sapiens)
U2 snRNP [nucleoplasm] (Homo sapiens)
DDX46 [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal Bact complex (Homo sapiens)
Spliceosomal B complex [nucleoplasm] (Homo sapiens)
U2 snRNP [nucleoplasm] (Homo sapiens)
DDX46 [nucleoplasm] (Homo sapiens)
Spliceosomal Bact complex [nucleoplasm] (Homo sapiens)
U2 snRNP [nucleoplasm] (Homo sapiens)
DDX46 [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal C* complex (Homo sapiens)
Spliceosomal C complex [nucleoplasm] (Homo sapiens)
U2 12S snRNP [nucleoplasm] (Homo sapiens)
DDX46 [nucleoplasm] (Homo sapiens)
Spliceosomal C* complex [nucleoplasm] (Homo sapiens)
U2 12S snRNP [nucleoplasm] (Homo sapiens)
DDX46 [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal P complex and exon ligation (Homo sapiens)
Spliceosomal C* complex [nucleoplasm] (Homo sapiens)
U2 12S snRNP [nucleoplasm] (Homo sapiens)
DDX46 [nucleoplasm] (Homo sapiens)
Spliceosomal P complex [nucleoplasm] (Homo sapiens)
U2 12S snRNP [nucleoplasm] (Homo sapiens)
DDX46 [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal Pre-B complex (Homo sapiens)
Spliceosomal A complex [nucleoplasm] (Homo sapiens)
U2 snRNP [nucleoplasm] (Homo sapiens)
DDX46 [nucleoplasm] (Homo sapiens)
Spliceosomal Pre-B complex [nucleoplasm] (Homo sapiens)
U2 snRNP [nucleoplasm] (Homo sapiens)
DDX46 [nucleoplasm] (Homo sapiens)
Spliceosomal P complex dissociates yielding the intron-containing complex (ILS) and the spliced mRNP (new) (Homo sapiens)
Intron Lariat Spliceosome (ILS) [nucleoplasm] (Homo sapiens)
U2 12S snRNP [nucleoplasm] (Homo sapiens)
DDX46 [nucleoplasm] (Homo sapiens)
Spliceosomal P complex [nucleoplasm] (Homo sapiens)
U2 12S snRNP [nucleoplasm] (Homo sapiens)
DDX46 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q7L014 DDX46
Gene Names
DDX46, KIAA0801
Chain
initiator methionine:, chain:2-1031
Reference Genes
BioGPS Gene:9879 DDX46
COSMIC (genes):DDX46 DDX46
CTD Gene:9879 DDX46
dbSNP Gene:9879 DDX46
ENSEMBL:ENSG00000145833 DDX46
ENSEMBL_homo_sapiens_GENE:ENSG00000145833.16 DDX46
HGNC:18681 DDX46
KEGG Gene (Homo sapiens):9879 DDX46
Monarch:9879 DDX46
NCBI Gene:9879 DDX46
OMIM:617848 DDX46
UCSC:Q7L014 DDX46
Reference Transcript
RefSeq:NM_001300860.1 DDX46
RefSeq:NM_014829.3 DDX46
Other Identifiers
11727818_a_at
16989332
202462_PM_s_at
202462_s_at
2829489
2829490
2829491
2829493
2829494
2829496
2829498
2829500
2829503
2829504
2829505
2829506
2829509
2829510
2829515
2829516
2829518
2829521
2829522
2829524
2829525
2829527
2829528
2829532
2829533
2829534
2829535
33237_at
8108134
9879
A_14_P102864
A_14_P106105
A_23_P30377
GE53498
GO:0000166
GO:0000398
GO:0001650
GO:0003676
GO:0003723
GO:0003724
GO:0003824
GO:0004386
GO:0005515
GO:0005524
GO:0005634
GO:0005654
GO:0005681
GO:0005684
GO:0005686
GO:0005730
GO:0006397
GO:0008380
GO:0015030
GO:0016071
GO:0016607
GO:0016787
GO:0016887
GO:0043226
GO:0065003
GO:0140098
GO:0140657
GO:1903241
HMNXSV003009911
PH_hs_0026481
TC05003400.hg
g7662317_3p_s_at
Participates
as a component of
U2 snRNP [nucleoplasm] (Homo sapiens)
U2 12S snRNP [nucleoplasm] (Homo sapiens)
Inferred To
Ddx46 [nucleoplasm]
(Rattus norvegicus)
Prp5 [nucleoplasm]
(Drosophila melanogaster)
DDX46 [nucleoplasm]
(Bos taurus)
DDX46 [nucleoplasm]
(Canis familiaris)
DDX46 [nucleoplasm]
(Danio rerio)
DDX46 [nucleoplasm]
(Dictyostelium discoideum)
DDX46 [nucleoplasm]
(Gallus gallus)
DDX46 [nucleoplasm]
(Mus musculus)
DDX46 [nucleoplasm]
(Plasmodium falciparum)
DDX46 [nucleoplasm]
(Schizosaccharomyces pombe)
DDX46 [nucleoplasm]
(Sus scrofa)
ddx-46 [nucleoplasm]
(Caenorhabditis elegans)
Ghost homologue of DDX46 [nucleoplasm]
(Xenopus tropicalis)
Cross References
RefSeq
NP_055644.2
,
NP_001287789.1
OpenTargets
ENSG00000145833
HPA
ENSG00000145833-DDX46
GeneCards
Q7L014
Ensembl
ENST00000354283
,
ENSG00000145833
,
ENSP00000346236
PRO
Q7L014
Pharos - Targets
Q7L014
HMDB Protein
HMDBP11677
PDB
6Y5Q
,
6Y53
,
7EVO
,
6Y50
,
7VPX
,
7Q3L
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P62304 SNRPE
2
SNRPE [nucleoplasm]
(R-HSA-71905)
SNRPE [cytosol]
(R-HSA-191782)
0.527
2
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