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DHX15 [nucleoplasm]
Stable Identifier
R-HSA-5688097
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 ecNumber3.6.4.13/ecNumber, DHX15_HUMAN, hPrp43
Locations in the PathwayBrowser for interactor UniProt:Q8N5A5 ZGPAT
Expand all
Metabolism of RNA (Homo sapiens)
Processing of Capped Intron-Containing Pre-mRNA (Homo sapiens)
mRNA Splicing (Homo sapiens)
mRNA Splicing - Major Pathway (Homo sapiens)
Disassembly of the Intron Lariat Spliceosome (new) (Homo sapiens)
DHX15 [nucleoplasm] (Homo sapiens)
Spliceosomal P complex dissociates yielding the intron-containing complex (ILS) and the spliced mRNP (new) (Homo sapiens)
DHX15 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:O43143 DHX15
Gene Names
DHX15, DBP1, DDX15
Chain
chain:1-795
Reference Genes
BioGPS Gene:1665 DHX15
COSMIC (genes):DHX15 DHX15
CTD Gene:1665 DHX15
dbSNP Gene:1665 DHX15
ENSEMBL:ENSG00000109606 DHX15
HGNC:2738 DHX15
KEGG:hsa:1665 DHX15
Monarch:1665 DHX15
NCBI Gene:1665 DHX15
OMIM:603403 DHX15
UCSC:O43143 DHX15
Reference Transcript
RefSeq:NM_001358.2 DHX15
Other Identifiers
11743114_at
1665
16974873
201385_PM_at
201385_at
201386_PM_s_at
201386_s_at
2763806
2763813
2763814
2763815
2763816
2763817
2763818
2763820
2763821
2763824
2763825
2763826
2763827
2763828
2763829
2763830
2763831
2763833
2763835
2763836
2763842
2763843
2763845
2763846
2763847
2763848
2763849
2763850
2763851
2763852
2763853
2763854
35306_at
8099649
A_19_P00806302
A_23_P69826
GE53029
GO:0000398
GO:0002376
GO:0003676
GO:0003723
GO:0003724
GO:0003725
GO:0003824
GO:0004386
GO:0005515
GO:0005524
GO:0005634
GO:0005654
GO:0005681
GO:0005689
GO:0005730
GO:0006397
GO:0008186
GO:0008380
GO:0009636
GO:0016071
GO:0016607
GO:0016787
GO:0016887
GO:0042742
GO:0043123
GO:0043226
GO:0043279
GO:0045087
GO:0051607
GO:0071008
GO:0098542
GO:0140098
GO:0140374
GO:0140657
HMNXSV003003878
Hs.287588.0.S1_3p_at
ILMN_1754839
ILMN_2168449
PH_hs_0000577
TC04001086.hg
g4557516_3p_at
g9624452_3p_a_at
Participates
as an output of
Disassembly of the Intron Lariat Spliceosome (new) (Homo sapiens)
as a component of
U2 snRNP [nucleoplasm] (Homo sapiens)
Intron Lariat Spliceosome (ILS) [nucleoplasm] (Homo sapiens)
U2 12S snRNP [nucleoplasm] (Homo sapiens)
as an input of
Spliceosomal P complex dissociates yielding the intron-containing complex (ILS) and the spliced mRNP (new) (Homo sapiens)
Inferred To
Ghost homologue of DHX15 [nucleoplasm]
(Danio rerio)
DHX15 [nucleoplasm]
(Bos taurus)
DHX15 [nucleoplasm]
(Caenorhabditis elegans)
DHX15 [nucleoplasm]
(Canis familiaris)
DHX15 [nucleoplasm]
(Dictyostelium discoideum)
DHX15 [nucleoplasm]
(Drosophila melanogaster)
DHX15 [nucleoplasm]
(Gallus gallus)
DHX15 [nucleoplasm]
(Mus musculus)
DHX15 [nucleoplasm]
(Plasmodium falciparum)
DHX15 [nucleoplasm]
(Schizosaccharomyces pombe)
DHX15 [nucleoplasm]
(Sus scrofa)
dhx15 [nucleoplasm]
(Xenopus tropicalis)
Dhx15 [nucleoplasm]
(Rattus norvegicus)
Cross References
RefSeq
NP_001349.2
OpenTargets
ENSG00000109606
ENSEMBL
ENSP00000336741
,
ENST00000336812
HPA
ENSG00000109606-DHX15
PRO
O43143
Pharos - Targets
O43143
GlyGen
O43143
HMDB Protein
HMDBP11694
PDB
6ID1
,
5XDR
,
8EJM
,
6SH6
,
6SH7
Interactors (30)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q96I25 RBM17
1
RBM17 [nucleoplasm]
(R-HSA-8865891)
0.882
12
UniProt:Q8N5A5-2 ZGPAT
0.85
12
UniProt:P52756 RBM5
1
RBM5 [nucleoplasm]
(R-HSA-72049)
0.806
15
UniProt:O15226 NKRF
0.666
4
UniProt:Q8N5A5 ZGPAT
0.666
6
UniProt:O75533 SF3B1
1
SF3B1 [nucleoplasm]
(R-HSA-71968)
0.643
3
UniProt:Q96RS6 NUDC1
0.643
4
UniProt:Q15459 SF3A1
1
SF3A1 [nucleoplasm]
(R-HSA-71962)
0.643
3
UniProt:P98175 RBM10
1
RBM10 [nucleoplasm]
(R-HSA-9770262)
0.632
3
UniProt:Q9UBB9 TFIP11
1
TFIP11 [nucleoplasm]
(R-HSA-8869310)
0.597
4
UniProt:Q15428 SF3A2
1
SF3A2 [nucleoplasm]
(R-HSA-71964)
0.564
2
UniProt:Q8N302 AGGF1
2
AGGF(1-290)-RAF1(279-648) fusion [cytosol]
(R-HSA-6802255)
AGGF(1-290)-p-RAF1(279-648) fusion [cytosol]
(R-HSA-6802507)
0.556
3
UniProt:A0A0S2Z6H0 A0A0S2Z6H0
0.556
3
UniProt:O95678 KRT75
1
KRT75 [cytosol]
(R-HSA-6809652)
0.556
3
UniProt:O95872 GPAN1
0.556
3
UniProt:P51114-2 FXR1
0.556
3
UniProt:Q9P1Y5-2 Q9P1Y52
0.556
3
UniProt:Q86XP3 DDX42
1
DDX42 [nucleoplasm]
(R-HSA-8867894)
0.547
2
UniProt:P19320 VCAM1
1
VCAM1 [plasma membrane]
(R-HSA-197834)
0.527
4
UniProt:P16383 GCFC2
1
GCFC2 [nucleoplasm]
(R-HSA-8869311)
0.527
3
UniProt:Q15427 SF3B4
1
SF3B4 [nucleoplasm]
(R-HSA-71975)
0.527
2
UniProt:Q8N1G2 CMTR1
0.527
2
UniProt:Q1ED39 KNOP1
0.527
2
UniProt:Q15393 SF3B3
1
SF3B3 [nucleoplasm]
(R-HSA-71973)
0.527
2
UniProt:Q8IWX8 CHERP
1
CHERP [nucleoplasm]
(R-HSA-8865901)
0.527
2
UniProt:P78362 SRPK2
1
SRPK2 [cytosol]
(R-HSA-9729332)
0.527
2
UniProt:Q13435 SF3B2
1
SF3B2 [nucleoplasm]
(R-HSA-71971)
0.527
2
UniProt:Q13618 CUL3
3
G76-NEDD8-K712-CUL3 [cytosol]
(R-HSA-8952516)
CUL3 [nucleoplasm]
(R-HSA-5635033)
CUL3 [cytosol]
(R-HSA-975979)
0.527
2
UniProt:Q8IWZ8 SUGP1
1
SUGP1 [nucleoplasm]
(R-HSA-72043)
0.508
2
UniProt:P03372 ESR1
10
ESR1 [cytosol]
(R-HSA-9020968)
ESR1 [nucleoplasm]
(R-HSA-446168)
Me260-PalmS-ESR1 [plasma membrane]
(R-HSA-9637788)
PalmS-ESR1 [plasma membrane]
(R-HSA-9021057)
PalmS-ESR1 [cytosol]
(R-HSA-9020974)
Me260-ESR1 [cytosol]
(R-HSA-9632177)
p-S167-ESR1 [cytosol]
(R-HSA-9841254)
p-S167-ESR1 [nucleoplasm]
(R-HSA-9841867)
monoSUMO1-5K-ESR1 [nucleoplasm]
(R-HSA-4090302)
p-S118-ESR1 [nucleoplasm]
(R-HSA-9024210)
0.462
2
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