Reactome | TMEM126B [mitochondrial inner membrane]

TMEM126B [mitochondrial inner membrane]

Stable Identifier

R-HSA-5689046

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial inner membrane

Synonyms

Complex I assembly factor TMEM126B, mitochondrial, T126B_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q8IUX1 TMEM126B

Gene Names

TMEM126B, HT007

Chain

initiator methionine:, chain:2-230

Reference Genes

BioGPS Gene:55863 TMEM126B

COSMIC (genes):TMEM126B TMEM126B

CTD Gene:55863 TMEM126B

dbSNP Gene:55863 TMEM126B

ENSEMBL:ENSG00000171204 TMEM126B

HGNC:30883 TMEM126B

KEGG:hsa:55863 TMEM126B

Monarch:55863 TMEM126B

NCBI Gene:55863 TMEM126B

OMIM:615533 TMEM126B

UCSC:Q8IUX1 TMEM126B

Reference Transcript

Other Identifiers

11722392_a_at

11722393_s_at

11757380_s_at

11760713_at

1554537_PM_at

1554537_at

16729670

221622_PM_s_at

221622_s_at

3342984

3342986

3342987

3342988

3342989

3342990

3342991

3342992

3342993

3342994

3342995

3342996

3342997

3342998

3342999

3343000

45725_at

55863

7942879

A_14_P107133

A_23_P2129

GE85480

GO:0003674

GO:0005515

GO:0005739

GO:0005743

GO:0007005

GO:0016020

GO:0031966

GO:0032094

GO:0032981

GO:0043226

GO:0065003

HMNXSV003025240

Hs2.24371.2.S1_3p_at

ILMN_1766851

ILMN_2145518

PH_hs_0026457

PH_hs_0034023

TC11000864.hg

TC11002809.hg

g12005514_3p_a_at

Participates

as a component of

MCIA complex [mitochondrial inner membrane] (Homo sapiens)

Inferred To

Tmem126 [mitochondrial inner membrane] (Drosophila melanogaster)

Ghost homologue of TMEM126B [mitochondrial inner membrane] (Caenorhabditis elegans)

Tmem126b [mitochondrial inner membrane] (Mus musculus)

Tmem126b [mitochondrial inner membrane] (Rattus norvegicus)

tmem126a [mitochondrial inner membrane] (Danio rerio)

tmem126a [mitochondrial inner membrane] (Xenopus tropicalis)

TMEM126A [mitochondrial inner membrane] (Gallus gallus)

TMEM126B [mitochondrial inner membrane] (Bos taurus)

TMEM126B [mitochondrial inner membrane] (Canis familiaris)

TMEM126B [mitochondrial inner membrane] (Sus scrofa)

Cross References

ENSEMBL

ENST00000534341, ENST00000358867, ENSP00000433471, ENSG00000171204, ENSP00000377039, ENSP00000351737, ENST00000393375

OpenTargets

ENSG00000171204

GeneCards

TMEM126B

HPA

ENSG00000171204-TMEM126B

PRO

Q8IUX1

Pharos - Targets

Q8IUX1

Orphanet

TMEM126B

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9BQ95 ECSIT	2	ECSIT [cytosol] (R-HSA-168064) ECSIT [mitochondrial inner membrane] (R-HSA-5689047)	0.527	3
UniProt:Q9P0J0 NDUFA13	8	NDUFA13 [mitochondrial inner membrane] (R-HSA-59936) NDUFA13(41-49) [mitochondrial inner membrane] (R-HSA-9839958) NDUFA13(100-108) [mitochondrial inner membrane] (R-HSA-9839959) NDUFA13(109-144) [mitochondrial inner membrane] (R-HSA-9839968) NDUFA13(2-19) [mitochondrial inner membrane] (R-HSA-9839966) NDUFA13(69-99) [mitochondrial inner membrane] (R-HSA-9839964) NDUFA13(20-40) [mitochondrial inner membrane] (R-HSA-9839963) NDUFA13(50-68) [mitochondrial inner membrane] (R-HSA-9839961)	0.527	3
UniProt:Q9NPL8 TIMMDC1	1	TIMMDC1 [mitochondrial inner membrane] (R-HSA-5689720)	0.527	2