Reactome | NDUFAF1 [mitochondrial inner membrane]

NDUFAF1 [mitochondrial inner membrane]

Stable Identifier

R-HSA-5689050

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial inner membrane

Synonyms

Complex I intermediate-associated protein 30, mitochondrial, CIA30_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9Y375 NDUFAF1

Gene Names

NDUFAF1, CIA30, CGI-65

Chain

transit peptide:1-24, chain:25-327

Reference Genes

BioGPS Gene:51103 NDUFAF1

COSMIC (genes):NDUFAF1 NDUFAF1

CTD Gene:51103 NDUFAF1

dbSNP Gene:51103 NDUFAF1

ENSEMBL:ENSG00000137806 NDUFAF1

HGNC:18828 NDUFAF1

KEGG:hsa:51103 NDUFAF1

Monarch:51103 NDUFAF1

NCBI Gene:51103 NDUFAF1

OMIM:606934 NDUFAF1

UCSC:Q9Y375 NDUFAF1

Reference Transcript

Other Identifiers

11722877_a_at

11763826_x_at

16807613

204125_PM_at

204125_at

3619992

3619993

3619994

3619995

3619996

3619997

3619998

3619999

3620000

3620001

3620003

3620004

3620005

41410_at

41411_at

51103

7987642

A_23_P26254

GE58650

GO:0005515

GO:0005739

GO:0005743

GO:0005759

GO:0005829

GO:0006091

GO:0006120

GO:0032981

GO:0043226

GO:0051082

GO:0051131

GO:0065003

HMNXSV003007445

HMNXSV003011211

HMNXSV003015950

ILMN_1754421

PH_hs_0005927

PH_hs_0031511

TC15001249.hg

g7705778_3p_at

Participates

as a component of

MCIA complex [mitochondrial inner membrane] (Homo sapiens)

Inferred To

NDUFAF1 [mitochondrial inner membrane] (Bos taurus)

NDUFAF1 [mitochondrial inner membrane] (Canis familiaris)

NDUFAF1 [mitochondrial inner membrane] (Gallus gallus)

NDUFAF1 [mitochondrial inner membrane] (Sus scrofa)

CIA30 [mitochondrial inner membrane] (Drosophila melanogaster)

Ndufaf1 [mitochondrial inner membrane] (Mus musculus)

Ndufaf1 [mitochondrial inner membrane] (Rattus norvegicus)

ndufaf1 [mitochondrial inner membrane] (Danio rerio)

ndufaf1 [mitochondrial inner membrane] (Xenopus tropicalis)

nuaf-1 [mitochondrial inner membrane] (Caenorhabditis elegans)

Cross References

ENSEMBL

ENSP00000260361, ENST00000560978, ENST00000260361, ENSP00000453944

OpenTargets

ENSG00000137806

HPA

ENSG00000137806-NDUFAF1

PRO

Q9Y375

Pharos - Targets

Q9Y375

Orphanet

NDUFAF1

HMDB Protein

HMDBP08886

Interactors (12)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O75489 NDUFS3	2	NDUFS3 [mitochondrial matrix] (R-HSA-163927) NDUFS3 [cytosol] (R-HSA-9714751)	0.788	6
UniProt:Q9NPL8 TIMMDC1	1	TIMMDC1 [mitochondrial inner membrane] (R-HSA-5689720)	0.643	5
UniProt:Q9BQ95 ECSIT	2	ECSIT [cytosol] (R-HSA-168064) ECSIT [mitochondrial inner membrane] (R-HSA-5689047)	0.643	5
UniProt:O43920 NDUFS5	1	NDUFS5 [mitochondrial inner membrane] (R-HSA-60226)	0.643	4
UniProt:Q9P0J0 NDUFA13	8	NDUFA13 [mitochondrial inner membrane] (R-HSA-59936) NDUFA13(41-49) [mitochondrial inner membrane] (R-HSA-9839958) NDUFA13(100-108) [mitochondrial inner membrane] (R-HSA-9839959) NDUFA13(109-144) [mitochondrial inner membrane] (R-HSA-9839968) NDUFA13(2-19) [mitochondrial inner membrane] (R-HSA-9839966) NDUFA13(69-99) [mitochondrial inner membrane] (R-HSA-9839964) NDUFA13(20-40) [mitochondrial inner membrane] (R-HSA-9839963) NDUFA13(50-68) [mitochondrial inner membrane] (R-HSA-9839961)	0.643	4
UniProt:Q9BRI3 SLC30A2	2	SLC30A2 [endosome membrane] (R-HSA-435363) SLC30A2 [synaptic vesicle membrane] (R-HSA-4084714)	0.556	3
UniProt:Q8N661 TMEM86B	1	TMEM86B [endoplasmic reticulum membrane] (R-HSA-8874443)	0.556	3
UniProt:Q16581 C3AR1	3	C3AR1 [plasma membrane] (R-HSA-444727) C3AR1 [azurophil granule membrane] (R-HSA-6799517) C3AR1 [specific granule membrane] (R-HSA-6799516)	0.527	2
UniProt:Q9P032 NDUFAF4	1	NDUFAF4 [mitochondrial inner membrane] (R-HSA-5689124)	0.527	4
UniProt:Q9H8X2 IPPK	2	IPPK [cytosol] (R-HSA-1604598) IPPK [nucleoplasm] (R-HSA-2023949)	0.527	2
UniProt:Q9BU61 NDUFAF3	1	NDUFAF3 [mitochondrial inner membrane] (R-HSA-5689126)	0.527	3
UniProt:Q16625 OCLN	4	OCLN [plasma membrane] (R-HSA-351846) OCLN(321-522) [plasma membrane] (R-HSA-351873) OCLN(1-320) [plasma membrane] (R-HSA-351854) OCLN [cell junction] (R-HSA-2160944)	0.527	3

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