(Glc)3(GlcNAc)2(Man)9-SERPINA1 [endoplasmic reticulum lumen]

Stable Identifier
R-HSA-5689435
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum lumen
Synonyms
alpha1-antitrypsin
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:P01009 SERPINA1
Gene Names
SERPINA1, AAT, PI, PRO0684, PRO2209
Chain
signal peptide:1-24, chain:25-418, peptide:375-418
Reference Genes
BioGPS Gene:5265 SERPINA1
COSMIC (genes):SERPINA1 SERPINA1
CTD Gene:5265 SERPINA1
dbSNP Gene:5265 SERPINA1
ENSEMBL:ENSG00000197249 SERPINA1
HGNC:8941 SERPINA1
KEGG Gene (Homo sapiens):5265 SERPINA1
Monarch:5265 SERPINA1
NCBI Gene:5265 SERPINA1
OMIM:107400 SERPINA1
UCSC:P01009 SERPINA1
Reference Transcript
Other Identifiers
0001400452
11721454_a_at
11721455_s_at
11721456_x_at
11721457_a_at
16796262
202833_s_at
211429_s_at
230318_at
3577624
3577625
3577626
3577627
3577628
3577629
3577630
3577631
3577632
3577633
3577635
3577636
3577642
3577649
3577651
3577652
36781_at
5265
7981068
A_23_P218111
A_33_P3289659
GE62796
GO:0002020
GO:0002376
GO:0002576
GO:0003674
GO:0004867
GO:0005515
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005737
GO:0005783
GO:0005788
GO:0005794
GO:0006464
GO:0006810
GO:0006888
GO:0006950
GO:0006953
GO:0007596
GO:0007599
GO:0008150
GO:0010466
GO:0010951
GO:0016192
GO:0019899
GO:0022607
GO:0030134
GO:0030234
GO:0030414
GO:0031012
GO:0031093
GO:0031410
GO:0033116
GO:0042802
GO:0043226
GO:0043231
GO:0043312
GO:0043687
GO:0044267
GO:0048208
GO:0061024
GO:0062023
GO:0065003
GO:0070062
GO:1904813
HMNXSV003030416
HMNXSV003046236
Hs.297681.4.A1_3p_at
ILMN_1686098
ILMN_1745961
ILMN_2256050
ILMN_2338452
ILMN_2404154
K01396_at
PH_hs_0028142
PH_hs_0036763
TC14001466.hg
TC14002135.hg
g4505792_3p_a_at
Participates
as a member of
Other forms of this molecule
SERPINA1 [platelet alpha granule lumen]
SERPINA1 [extracellular region]
SERPINA1 [ficolin-1-rich granule lumen]
(Glc)3(GlcNAc)2(Man)9-SERPINA1 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(Glc)3(GlcNAc)2(Man)9-SERPINA1 [COPII-coated ER to Golgi transport vesicle]
p-SERPINA1 [endoplasmic reticulum lumen]
SERPINA1 [endoplasmic reticulum lumen]
Inferred To
Spn28Dc [endoplasmic reticulum lumen] (Drosophila melanogaster)
Spn88Ea [endoplasmic reticulum lumen] (Drosophila melanogaster)
Spn42Dc [endoplasmic reticulum lumen] (Drosophila melanogaster)
Spn55B [endoplasmic reticulum lumen] (Drosophila melanogaster)
LOC100621494 [endoplasmic reticulum lumen] (Sus scrofa)
srp-2 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
serpina3 [endoplasmic reticulum lumen] (Xenopus tropicalis)
serpina3m [endoplasmic reticulum lumen] (Xenopus tropicalis)
Spn53F [endoplasmic reticulum lumen] (Drosophila melanogaster)
srp-8 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
SPIA4 [endoplasmic reticulum lumen] (Gallus gallus)
Spn28F [endoplasmic reticulum lumen] (Drosophila melanogaster)
Spn43Aa [endoplasmic reticulum lumen] (Drosophila melanogaster)
Spn43Ad [endoplasmic reticulum lumen] (Drosophila melanogaster)
SPIA1 [endoplasmic reticulum lumen] (Gallus gallus)
Spn42Dd [endoplasmic reticulum lumen] (Drosophila melanogaster)
srp-1 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
(Glc)3(GlcNAc)2(Man)9-SERPINA1 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
(Glc)3(GlcNAc)2(Man)9-SERPINA1 [endoplasmic reticulum lumen] (Danio rerio)
(Glc)3(GlcNAc)2(Man)9-SERPINA1 [endoplasmic reticulum lumen] (Xenopus tropicalis)
Spn38F [endoplasmic reticulum lumen] (Drosophila melanogaster)
LOC105948230 [endoplasmic reticulum lumen] (Xenopus tropicalis)
Spn28B [endoplasmic reticulum lumen] (Drosophila melanogaster)
SPIA9 [endoplasmic reticulum lumen] (Gallus gallus)
Spn28Da [endoplasmic reticulum lumen] (Drosophila melanogaster)
serpina7 [endoplasmic reticulum lumen] (Danio rerio)
srp-7 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
Homologues of (Glc)3(GlcNAc)2(Man)9-SERPINA1 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
Homologues of (Glc)3(GlcNAc)2(Man)9-SERPINA1 [endoplasmic reticulum lumen] (Danio rerio)
Homologues of (Glc)3(GlcNAc)2(Man)9-SERPINA1 [endoplasmic reticulum lumen] (Drosophila melanogaster)
Homologues of (Glc)3(GlcNAc)2(Man)9-SERPINA1 [endoplasmic reticulum lumen] (Gallus gallus)
Homologues of (Glc)3(GlcNAc)2(Man)9-SERPINA1 [endoplasmic reticulum lumen] (Sus scrofa)
Homologues of (Glc)3(GlcNAc)2(Man)9-SERPINA1 [endoplasmic reticulum lumen] (Xenopus tropicalis)
Spn42Da [endoplasmic reticulum lumen] (Drosophila melanogaster)
serpina1 [endoplasmic reticulum lumen] (Danio rerio)
serpina1 [endoplasmic reticulum lumen] (Xenopus tropicalis)
SPIA3 [endoplasmic reticulum lumen] (Gallus gallus)
Serpina1 [endoplasmic reticulum lumen] (Rattus norvegicus)
nec [endoplasmic reticulum lumen] (Drosophila melanogaster)
serpina1l [endoplasmic reticulum lumen] (Danio rerio)
LOC100488834 [endoplasmic reticulum lumen] (Xenopus tropicalis)
Spn43Ab [endoplasmic reticulum lumen] (Drosophila melanogaster)
Spn42Db [endoplasmic reticulum lumen] (Drosophila melanogaster)
srp-3 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
Spn42De [endoplasmic reticulum lumen] (Drosophila melanogaster)
Spn100A [endoplasmic reticulum lumen] (Drosophila melanogaster)
SERPINA1 [endoplasmic reticulum lumen] (Bos taurus)
SERPINA1 [endoplasmic reticulum lumen] (Canis familiaris)
SERPINA1 [endoplasmic reticulum lumen] (Sus scrofa)
si:ch211-186e20.7 [endoplasmic reticulum lumen] (Danio rerio)
Serpina1c [endoplasmic reticulum lumen] (Mus musculus)
Spn31A [endoplasmic reticulum lumen] (Drosophila melanogaster)
srp-6 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
si:ch211-186e20.2 [endoplasmic reticulum lumen] (Danio rerio)
Dmel\CG43366 [endoplasmic reticulum lumen] (Drosophila melanogaster)
Spn27A [endoplasmic reticulum lumen] (Drosophila melanogaster)
LOC110439158 [endoplasmic reticulum lumen] (Danio rerio)
SPIA5 [endoplasmic reticulum lumen] (Gallus gallus)
Spn28Db [endoplasmic reticulum lumen] (Drosophila melanogaster)
Spn47C [endoplasmic reticulum lumen] (Drosophila melanogaster)
Spn88Eb [endoplasmic reticulum lumen] (Drosophila melanogaster)
Modified Residues
Name
N4-(N-acetylamino)glucosyl-L-asparagine (N-{alpha-Glc-(1->2)-alpha-Glc-(1->3)-alpha-Glc-(1->3)-alpha-Man-(1->2)-alpha-Man-(1->2)-alpha-Man-(1->3)-(alpha-Man-(1->2)-alpha-Man-(1->3)-(alpha-Man-(1->2)-alpha-Man-(1->6))-alpha-Man-(1->6))-beta-Man-(1->4)-beta-GlcNAc-(1->4)-beta-GlcNAc}-L-Asn residue (ChEBI:59084)) at unknown position
Modification
N-{alpha-Glc-(1->2)-alpha-Glc-(1->3)-alpha-Glc-(1->3)-alpha-Man-(1->2)-alpha-Man-(1->2)-alpha-Man-(1->3)-(alpha-Man-(1->2)-alpha-Man-(1->3)-(alpha-Man-(1->2)-alpha-Man-(1->6))-alpha-Man-(1->6))-beta-Man-(1->4)-beta-GlcNAc-(1->4)-beta-GlcNAc}-yl group (ChEBI:59084)
PsiMod Name
N4-(N-acetylamino)glucosyl-L-asparagine
PsiMod Definition
A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine.
Cross References
RefSeq
OpenTargets
GeneCards
HPA
Ensembl
PRO
Pharos - Targets
Orphanet
GlyGen
PDB
Interactors (1)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P43307 SSR1  1 0.524 4
Cite Us!