Reactome | CNIH3 [endoplasmic reticulum-Golgi intermediate compartment membrane]

CNIH3 [endoplasmic reticulum-Golgi intermediate compartment membrane]

Stable Identifier

R-HSA-5689785

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum-Golgi intermediate compartment membrane

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Homo sapiens)

- Post-translational protein modification (Homo sapiens)
  - Asparagine N-linked glycosylation (Homo sapiens)
    - Transport to the Golgi and subsequent modification (Homo sapiens)
      - ER to Golgi Anterograde Transport (Homo sapiens)
        
        COPII-mediated vesicle transport (Homo sapiens)
        
        BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Homo sapiens)
        
        COPII cargo:receptors [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
        
        CNIH2,3:GRIA1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
        
        CNIH2,3 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
        
        CNIH3 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)

Vesicle-mediated transport (Homo sapiens)

- Membrane Trafficking (Homo sapiens)
  - ER to Golgi Anterograde Transport (Homo sapiens)
    - COPII-mediated vesicle transport (Homo sapiens)
      - BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Homo sapiens)
        
        COPII cargo:receptors [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
        
        CNIH2,3:GRIA1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
        
        CNIH2,3 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
        
        CNIH3 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q8TBE1 CNIH3

Gene Names

CNIH3

Chain

chain:1-160

Reference Genes

BioGPS Gene:149111 CNIH3

COSMIC (genes):CNIH3 CNIH3

CTD Gene:149111 CNIH3

dbSNP Gene:149111 CNIH3

ENSEMBL:ENSG00000143786.8 CNIH3

HGNC:26802 CNIH3

KEGG Gene (Homo sapiens):149111 CNIH3

Monarch:149111 CNIH3

NCBI Gene:149111 CNIH3

UCSC:Q8TBE1 CNIH3

Reference Transcript

RefSeq:NM_152495.1 CNIH3

Other Identifiers

0004060471

11727045_at

149111

214841_PM_at

214841_at

2382529

2382530

2382548

2382552

2382564

2382565

2382567

2382568

34942_at

7910022

A_14_P100311

A_23_P384044

GE514176

GO:0005515

GO:0005622

GO:0005737

GO:0005783

GO:0005789

GO:0005886

GO:0012507

GO:0016020

GO:0016021

GO:0016192

GO:0023052

GO:0030425

GO:0031410

GO:0032281

GO:0032991

GO:0033116

GO:0043198

GO:0043226

GO:0045202

GO:0045211

GO:0055085

GO:2000311

Hs.13410.0.S1_3p_at

ILMN_1749071

PH_hs_0024602

Participates

as a member of

CNIH2,3 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)

Other forms of this molecule

CNIH3 [ER to Golgi transport vesicle membrane]

CNIH3 [endoplasmic reticulum membrane]

Inferred To

CNIH3 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)

CNIH3 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)

CNIH3 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Gallus gallus)

CNIH3 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Sus scrofa)

Cnih3 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)

Cnih3 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Rattus norvegicus)

cni [endoplasmic reticulum-Golgi intermediate compartment membrane] (Drosophila melanogaster)

cni-1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Caenorhabditis elegans)

si:dkey-1j5.3 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Danio rerio)

Cross References

RefSeq

NP_689708.1

OpenTargets

ENSG00000143786

HPA

ENSG00000143786-CNIH3

GeneCards

Q8TBE1

Ensembl

ENSG00000143786, ENST00000272133, ENSP00000272133

PRO

Q8TBE1

Pharos - Targets

Q8TBE1

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O15554 KCNN4	1	KCNN4 [plasma membrane] (R-HSA-977543)	0.556	3
UniProt:Q96CV9 OPTN	5	OPTN [recycling endosome membrane] (R-HSA-8854141) p-S177-OPTN [nucleoplasm] (R-HSA-2562595) p-S177-OPTN [cytosol] (R-HSA-2562525) OPTN [Golgi membrane] (R-HSA-2161111) OPTN [cytosol] (R-HSA-9687907)	0.556	3