Reactome | CNIH3 [endoplasmic reticulum-Golgi intermediate compartment membrane]

CNIH3 [endoplasmic reticulum-Golgi intermediate compartment membrane]

Stable Identifier

R-HSA-5689785

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum-Golgi intermediate compartment membrane

Locations in the PathwayBrowser

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Metabolism of proteins (Homo sapiens)

- Post-translational protein modification (Homo sapiens)
  - Asparagine N-linked glycosylation (Homo sapiens)
    - Transport to the Golgi and subsequent modification (Homo sapiens)
      - ER to Golgi Anterograde Transport (Homo sapiens)
        
        COPII-mediated vesicle transport (Homo sapiens)
        
        BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Homo sapiens)
        
        COPII cargo:receptors [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
        
        CNIH2,3:GRIA1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
        
        CNIH2,3 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
        
        CNIH3 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)

Vesicle-mediated transport (Homo sapiens)

- Membrane Trafficking (Homo sapiens)
  - ER to Golgi Anterograde Transport (Homo sapiens)
    - COPII-mediated vesicle transport (Homo sapiens)
      - BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Homo sapiens)
        
        COPII cargo:receptors [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
        
        CNIH2,3:GRIA1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
        
        CNIH2,3 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
        
        CNIH3 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q8TBE1 CNIH3

Gene Names

CNIH3

Chain

chain:1-160

Reference Genes

BioGPS Gene:149111 CNIH3

COSMIC (genes):CNIH3 CNIH3

CTD Gene:149111 CNIH3

dbSNP Gene:149111 CNIH3

ENSEMBL:ENSG00000143786 CNIH3

HGNC:26802 CNIH3

KEGG:hsa:149111 CNIH3

Monarch:149111 CNIH3

NCBI Gene:149111 CNIH3

UCSC:Q8TBE1 CNIH3

Reference Transcript

RefSeq:NM_152495.1 CNIH3

Other Identifiers

11727045_at

149111

214841_PM_at

214841_at

2382468

2382469

2382487

2382488

2382489

2382490

2382491

2382494

2382495

2382496

2382497

2382500

2382501

2382505

2382507

2382509

2382521

2382522

2382524

2382525

2382526

2382527

2382529

2382530

2382548

2382552

2382564

2382565

2382567

2382568

238503_PM_at

238503_at

34942_at

74194_at

77955_at

7910022

A_14_P100311

A_21_P0014635

A_23_P384044

GE514176

GE554517

GO:0005515

GO:0005789

GO:0005886

GO:0012507

GO:0016192

GO:0030425

GO:0032281

GO:0033116

GO:0043198

GO:0045202

GO:0045211

GO:2000311

HMNXSV003018949

HMNXSV003030409

HMNXSV003051810

Hs.131236.0.A1_3p_at

Hs.13410.0.S1_3p_at

ILMN_1749071

PH_hs_0024602

PH_hs_0035145

TC01005061.hg

Participates

as a member of

CNIH2,3 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)

Other forms of this molecule

CNIH3 [ER to Golgi transport vesicle membrane]

CNIH3 [endoplasmic reticulum membrane]

Inferred To

CNIH3 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)

CNIH3 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)

CNIH3 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Gallus gallus)

CNIH3 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Sus scrofa)

Cnih3 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)

Cnih3 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Rattus norvegicus)

cni [endoplasmic reticulum-Golgi intermediate compartment membrane] (Drosophila melanogaster)

cni-1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Caenorhabditis elegans)

Cross References

ENSEMBL

ENST00000272133, ENSP00000272133, ENSG00000143786

OpenTargets

ENSG00000143786

GeneCards

CNIH3

HPA

ENSG00000143786-CNIH3

PRO

Q8TBE1

Pharos - Targets

Q8TBE1

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O15554 KCNN4	1	KCNN4 [plasma membrane] (R-HSA-977543)	0.556	3
UniProt:A8MZ59 LEUTX	1	LEUTX [nucleoplasm] (R-HSA-9817277)	0.556	3
UniProt:Q96CV9 OPTN	6	p-S177,S473,S513-OPTN [cytosol] (R-HSA-9687840) OPTN [cytosol] (R-HSA-9687907) p-S177-OPTN [cytosol] (R-HSA-2562525) p-S177-OPTN [nucleoplasm] (R-HSA-2562595) OPTN [Golgi membrane] (R-HSA-2161111) OPTN [recycling endosome membrane] (R-HSA-8854141)	0.556	3