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LMAN2 [ER to Golgi transport vesicle membrane]
Stable Identifier
R-HSA-5689828
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
ER to Golgi transport vesicle membrane
Synonyms
VIP36
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Asparagine N-linked glycosylation (Homo sapiens)
Transport to the Golgi and subsequent modification (Homo sapiens)
ER to Golgi Anterograde Transport (Homo sapiens)
COPII-mediated vesicle transport (Homo sapiens)
BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Homo sapiens)
COPII cargo:receptors:v:SNAREs:GOLGA2:GORASP1:USO1 homodimer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Homo sapiens)
LMAN family receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
LMAN2 [ER to Golgi transport vesicle membrane] (Homo sapiens)
COPII coat binds TRAPPCII and RAB1:GDP (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Homo sapiens)
COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Homo sapiens)
LMAN family receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
LMAN2 [ER to Golgi transport vesicle membrane] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Homo sapiens)
COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Homo sapiens)
LMAN family receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
LMAN2 [ER to Golgi transport vesicle membrane] (Homo sapiens)
CSNK1D phosphorylates SEC23 (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Homo sapiens)
COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Homo sapiens)
LMAN family receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
LMAN2 [ER to Golgi transport vesicle membrane] (Homo sapiens)
COPII cargo:receptors:v:SNAREs:GOLGA2:GORASP1:USO1 homodimer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Homo sapiens)
LMAN family receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
LMAN2 [ER to Golgi transport vesicle membrane] (Homo sapiens)
Nucleotide exchange on RAB1 (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Homo sapiens)
COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Homo sapiens)
LMAN family receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
LMAN2 [ER to Golgi transport vesicle membrane] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Homo sapiens)
COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Homo sapiens)
LMAN family receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
LMAN2 [ER to Golgi transport vesicle membrane] (Homo sapiens)
RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Homo sapiens)
COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Homo sapiens)
LMAN family receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
LMAN2 [ER to Golgi transport vesicle membrane] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Homo sapiens)
COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Homo sapiens)
LMAN family receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
LMAN2 [ER to Golgi transport vesicle membrane] (Homo sapiens)
Vesicle budding (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Homo sapiens)
COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Homo sapiens)
LMAN family receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
LMAN2 [ER to Golgi transport vesicle membrane] (Homo sapiens)
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
ER to Golgi Anterograde Transport (Homo sapiens)
COPII-mediated vesicle transport (Homo sapiens)
BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Homo sapiens)
COPII cargo:receptors:v:SNAREs:GOLGA2:GORASP1:USO1 homodimer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Homo sapiens)
LMAN family receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
LMAN2 [ER to Golgi transport vesicle membrane] (Homo sapiens)
COPII coat binds TRAPPCII and RAB1:GDP (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Homo sapiens)
COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Homo sapiens)
LMAN family receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
LMAN2 [ER to Golgi transport vesicle membrane] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Homo sapiens)
COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Homo sapiens)
LMAN family receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
LMAN2 [ER to Golgi transport vesicle membrane] (Homo sapiens)
CSNK1D phosphorylates SEC23 (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Homo sapiens)
COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Homo sapiens)
LMAN family receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
LMAN2 [ER to Golgi transport vesicle membrane] (Homo sapiens)
COPII cargo:receptors:v:SNAREs:GOLGA2:GORASP1:USO1 homodimer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Homo sapiens)
LMAN family receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
LMAN2 [ER to Golgi transport vesicle membrane] (Homo sapiens)
Nucleotide exchange on RAB1 (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Homo sapiens)
COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Homo sapiens)
LMAN family receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
LMAN2 [ER to Golgi transport vesicle membrane] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Homo sapiens)
COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Homo sapiens)
LMAN family receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
LMAN2 [ER to Golgi transport vesicle membrane] (Homo sapiens)
RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Homo sapiens)
COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Homo sapiens)
LMAN family receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
LMAN2 [ER to Golgi transport vesicle membrane] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Homo sapiens)
COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Homo sapiens)
LMAN family receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
LMAN2 [ER to Golgi transport vesicle membrane] (Homo sapiens)
Vesicle budding (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Homo sapiens)
COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Homo sapiens)
LMAN family receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
LMAN2 [ER to Golgi transport vesicle membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q12907 LMAN2
Gene Names
LMAN2, C5orf8
Chain
signal peptide:1-44, chain:45-356
Reference Genes
BioGPS Gene:10960 LMAN2
COSMIC (genes):LMAN2 LMAN2
CTD Gene:10960 LMAN2
dbSNP Gene:10960 LMAN2
ENSEMBL:ENSG00000169223 LMAN2
HGNC:16986 LMAN2
KEGG:hsa:10960 LMAN2
Monarch:10960 LMAN2
NCBI Gene:10960 LMAN2
OMIM:609551 LMAN2
UCSC:Q12907 LMAN2
Reference Transcript
RefSeq:NM_006816.2 LMAN2
Other Identifiers
10960
11723919_x_at
17003208
200805_PM_at
200805_at
215656_3p_at
215656_PM_at
215656_at
2888693
2888699
2888700
2888701
2888702
2888703
2888704
2888705
2888706
2888707
2888708
2888709
2888710
2888711
2888713
2888716
2888717
2888718
2888719
36955_at
74891_at
74893_g_at
8116020
A_23_P9591
A_24_P9285
GE79770
GO:0000139
GO:0005515
GO:0005537
GO:0005615
GO:0005783
GO:0005789
GO:0005793
GO:0005794
GO:0005886
GO:0006888
GO:0006890
GO:0009986
GO:0015031
GO:0016020
GO:0016192
GO:0030134
GO:0030246
GO:0031072
GO:0031410
GO:0033116
GO:0043226
GO:0046872
GO:0050766
GO:0070062
HMNXSV003028588
Hs.306751.0.S1_3p_x_at
ILMN_1776963
PH_hs_0004382
PH_hs_0038805
RNA147690|p0794_imsncRNA587
TC05002103.hg
U10362_at
g5803022_3p_at
g5803022_3p_x_at
Participates
as a candidate of
LMAN family receptors [ER to Golgi transport vesicle membrane] (Homo sapiens)
Other forms of this molecule
LMAN2 [endoplasmic reticulum-Golgi intermediate compartment membrane]
LMAN2 [endoplasmic reticulum membrane]
Inferred To
LMAN2 [ER to Golgi transport vesicle membrane]
(Bos taurus)
LMAN2 [ER to Golgi transport vesicle membrane]
(Canis familiaris)
LMAN2 [ER to Golgi transport vesicle membrane]
(Dictyostelium discoideum)
LMAN2 [ER to Golgi transport vesicle membrane]
(Gallus gallus)
LMAN2 [ER to Golgi transport vesicle membrane]
(Mus musculus)
LMAN2 [ER to Golgi transport vesicle membrane]
(Sus scrofa)
Dmel\CG5510 [ER to Golgi transport vesicle membrane]
(Drosophila melanogaster)
ile-2 [ER to Golgi transport vesicle membrane]
(Caenorhabditis elegans)
lman2 [ER to Golgi transport vesicle membrane]
(Xenopus tropicalis)
Lman2 [ER to Golgi transport vesicle membrane]
(Rattus norvegicus)
Cross References
ENSEMBL
ENST00000303127
,
ENSP00000303366
,
ENSG00000169223
OpenTargets
ENSG00000169223
GeneCards
LMAN2
HPA
ENSG00000169223-LMAN2
PRO
Q12907
Pharos - Targets
Q12907
GlyGen
Q12907
HMDB Protein
HMDBP07782
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P13569 CFTR
17
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR [endosome membrane]
(R-HSA-6782965)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [lysosomal membrane]
(R-HSA-5627279)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
0.483
9
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