Reactome | ACOT7 [cytosol]

ACOT7 [cytosol]

Stable Identifier

R-HSA-5690040

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Cytosolic acyl coenzyme A thioester hydrolase ecNumber3.1.2.2/ecNumber, BACH_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O00154 ACOT7

Gene Names

ACOT7, BACH

Chain

chain:1-380

Reference Genes

BioGPS Gene:11332 ACOT7

COSMIC (genes):ACOT7 ACOT7

CTD Gene:11332 ACOT7

dbSNP Gene:11332 ACOT7

ENSEMBL:ENSG00000097021 ACOT7

ENSEMBL_homo_sapiens_GENE:ENSG00000097021.21 ACOT7

HGNC:24157 ACOT7

KEGG Gene (Homo sapiens):11332 ACOT7

Monarch:11332 ACOT7

NCBI Gene:11332 ACOT7

OMIM:602587 ACOT7

UCSC:O00154 ACOT7

Reference Transcript

Other Identifiers

11332

11717743_a_at

16681103

208002_PM_s_at

208002_s_at

215728_PM_s_at

215728_s_at

2394627

2394628

2394629

2394639

2394640

2394641

2394642

2394645

2394648

2394650

2394651

2394654

2394657

2394659

2394660

2394661

2394666

2394667

2394669

2394670

2394671

2394672

2394673

2394674

37945_at

75352_s_at

7912012

8099965

A_24_P205589

GE59558

GO:0000062

GO:0003824

GO:0005515

GO:0005576

GO:0005615

GO:0005634

GO:0005654

GO:0005737

GO:0005739

GO:0005829

GO:0006629

GO:0006631

GO:0006637

GO:0006790

GO:0008289

GO:0015937

GO:0016290

GO:0016787

GO:0016790

GO:0036042

GO:0036114

GO:0036116

GO:0042803

GO:0043226

GO:0051792

GO:0052689

GO:0055086

GO:0070062

GO:0102991

GO:1900535

GO:1901135

HMNXSV003006121

Hs.8679.2.S1_3p_a_at

ILMN_1719178

ILMN_1728883

ILMN_1740265

ILMN_1784756

ILMN_1788078

ILMN_2252621

ILMN_2332250

PH_hs_0025385

PH_hs_0033361

U91316_at

g6857796_3p_a_at

Participates

as a component of

ACOT7 hexamer [cytosol] (Homo sapiens)

Inferred To

ACOT7 [cytosol] (Bos taurus)

ACOT7 [cytosol] (Canis familiaris)

ACOT7 [cytosol] (Gallus gallus)

ACOT7 [cytosol] (Sus scrofa)

Acot7 [cytosol] (Mus musculus)

Acot7 [cytosol] (Rattus norvegicus)

acot7 [cytosol] (Xenopus tropicalis)

Cross References

RefSeq

NP_863656.1, NP_863655.1, NP_863654.1, NP_009205.3

OpenTargets

ENSG00000097021

GeneCards

O00154

HPA

ENSG00000097021-ACOT7

Ensembl

ENSP00000402532, ENST00000361521, ENST00000418124, ENST00000377860, ENSP00000476610, ENST00000377842, ENST00000377855, ENSP00000367086, ENSP00000367091, ENST00000377845, ENSP00000367073, ENSP00000354615, ENSP00000367076, ENST00000608083, ENSG00000097021

PRO

O00154

Pharos - Targets

O00154

PDB

2QQ2

HMDB Protein

HMDBP01046

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9HCK8 CHD8	1	CHD8 [nucleoplasm] (R-HSA-3221598)	0.499	2
UniProt:P13569 CFTR	17	PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.483	8

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