Reactome | ACOT9 [mitochondrial matrix]

ACOT9 [mitochondrial matrix]

Stable Identifier

R-HSA-5690069

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial matrix

Synonyms

Acyl-coenzyme A thioesterase 9, mitochondrial, ACOT9_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9Y305 ACOT9

Gene Names

ACOT9, CGI-16

Chain

transit peptide:1-21, chain:22-439

Reference Genes

BioGPS Gene:23597 ACOT9

COSMIC (genes):ACOT9 ACOT9

CTD Gene:23597 ACOT9

dbSNP Gene:23597 ACOT9

ENSEMBL:ENSG00000123130 ACOT9

HGNC:17152 ACOT9

KEGG:hsa:23597 ACOT9

Monarch:23597 ACOT9

NCBI Gene:23597 ACOT9

OMIM:300862 ACOT9

UCSC:Q9Y305 ACOT9

Reference Transcript

Other Identifiers

11736329_a_at

11744488_a_at

11747153_x_at

11760790_at

17109780

221641_PM_s_at

221641_s_at

23597

239277_PM_at

239277_at

4002746

4002747

4002748

4002749

4002750

4002751

4002752

4002753

4002754

4002755

4002756

4002757

4002758

4002759

4002760

4002763

4002764

4002765

4002767

4002768

4002771

4002772

4002774

4002777

4002783

4002784

4002785

4002791

44213_at

63785_at

81062_at

8171802

A_23_P125624

A_24_P42501

GE58486

GE884041

GO:0003824

GO:0003986

GO:0005739

GO:0005759

GO:0006637

GO:0006790

GO:0016787

GO:0043226

GO:0047617

GO:0052689

GO:0052816

GO:0055086

GO:1901135

HMNXSV003000658

Hs.298885.0.A1_3p_at

ILMN_1658995

ILMN_2367070

PH_hs_0023589

TC0X000921.hg

g12005490_3p_a_at

Participates

as a member of

ACOT2,9, THEM4,5 dimer [mitochondrial matrix] (Homo sapiens)

Inferred To

ACOT9 [mitochondrial matrix] (Bos taurus)

ACOT9 [mitochondrial matrix] (Caenorhabditis elegans)

ACOT9 [mitochondrial matrix] (Canis familiaris)

ACOT9 [mitochondrial matrix] (Dictyostelium discoideum)

ACOT9 [mitochondrial matrix] (Gallus gallus)

ACOT9 [mitochondrial matrix] (Plasmodium falciparum)

ACOT9 [mitochondrial matrix] (Sus scrofa)

Acot9 [mitochondrial matrix] (Mus musculus)

Acot9 [mitochondrial matrix] (Rattus norvegicus)

Dmel\CG1635 [mitochondrial matrix] (Drosophila melanogaster)

acot9 [mitochondrial matrix] (Xenopus tropicalis)

acot9.2 [mitochondrial matrix] (Danio rerio)

Cross References

ENSEMBL

ENSP00000336580, ENSP00000368597, ENST00000379295, ENSP00000368605, ENST00000379303, ENST00000336430

OpenTargets

ENSG00000123130

HPA

ENSG00000123130-ACOT9

PRO

Q9Y305

Pharos - Targets

Q9Y305

GlyGen

Q9Y305

HMDB Protein

HMDBP10998

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104)	0.615	14
UniProt:P13671 C6	1	C6 [extracellular region] (R-HSA-173706)	0.527	3
UniProt:P53611 RABGGTB	2	RABGGTB [plasma membrane] (R-HSA-6801098) RABGGTB [cytosol] (R-HSA-8870419)	0.527	2
UniProt:P00740 F9	20	F9(227-461) R384L [plasma membrane] (R-HSA-9668263) 3OHD110-F9(29-461) N43L [endoplasmic reticulum lumen] (R-HSA-9673207) 3OHD110-F9(29-461) N46S [endoplasmic reticulum lumen] (R-HSA-9673232) 3OHD110-F9(29-461) N43Q [endoplasmic reticulum lumen] (R-HSA-9673217) 3OHD110-F9(29-461) N43W [endoplasmic reticulum lumen] (R-HSA-9673235) 12xCbxE-3D-F9(47-461) R191H [extracellular region] (R-HSA-9673404) F9(29-461) R43Q [extracellular region] (R-HSA-9673228) F9(29-461) R43W [extracellular region] (R-HSA-9673213) 12xCbxE-3D-F9(47-461) R191C [extracellular region] (R-HSA-9673391) F9(29-461) R46S [extracellular region] (R-HSA-9673193) 12xCbxE-3D-F9(47-461) R226W [extracellular region] (R-HSA-9673403) F9(29-461) R43L [extracellular region] (R-HSA-9673205) 12xCbxE-3D-F9(47-461) R226Q [extracellular region] (R-HSA-9673415) 12xCbxE-3D-F9(47-461) R226G [extracellular region] (R-HSA-9673418) F9(227-461) G409V [plasma membrane] (R-HSA-9671020) F9(227-461) I443T [plasma membrane] (R-HSA-9670908) F9(227-461) S411G [plasma membrane] (R-HSA-9671021) F9(227-461) G363E [plasma membrane] (R-HSA-9670894) F9(227-461) G363R [plasma membrane] (R-HSA-9670862) F9(227-461) D410H [plasma membrane] (R-HSA-9671007)	0.527	2

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