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p-T182 MAPKAPK5 binds DNAJB1
Stable Identifier
R-HSA-5690245
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
Locations in the PathwayBrowser
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Signal Transduction (Homo sapiens)
MAPK family signaling cascades (Homo sapiens)
MAPK6/MAPK4 signaling (Homo sapiens)
p-T182 MAPKAPK5 binds DNAJB1 (Homo sapiens)
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Cytosolic MAPKAPK5 forms a complex with DNAJB1 through an interaction mediated by the C-terminal tails of both proteins (Kostenko et al, 2014).
Literature References
PubMed ID
Title
Journal
Year
24309468
Phosphorylation of heat shock protein 40 (Hsp40/DnaJB1) by mitogen-activated protein kinase-activated protein kinase 5 (MK5/PRAK)
Jensen, KL
,
Kostenko, S
,
Moens, U
Int. J. Biochem. Cell Biol.
2014
Participants
Input
DNAJB1 [cytosol]
(Homo sapiens)
p-T182 MAPKAPK5 [cytosol]
(Homo sapiens)
Output
p-T182 MAPKAPK5:DNAJB1 [cytosol]
(Homo sapiens)
Participates
as an event of
MAPK6/MAPK4 signaling (Homo sapiens)
Orthologous Events
p-T182 MAPKAPK5 binds DNAJB1 (Bos taurus)
p-T182 MAPKAPK5 binds DNAJB1 (Danio rerio)
p-T182 MAPKAPK5 binds DNAJB1 (Gallus gallus)
p-T182 MAPKAPK5 binds DNAJB1 (Mus musculus)
p-T182 MAPKAPK5 binds DNAJB1 (Plasmodium falciparum)
p-T182 MAPKAPK5 binds DNAJB1 (Rattus norvegicus)
p-T182 MAPKAPK5 binds DNAJB1 (Sus scrofa)
Authored
Moens, U (2015-04-24)
Reviewed
Moens, U (2015-04-24)
Soulez, M (2015-05-12)
Mathien, S (2015-05-12)
Seternes, OM (2015-05-05)
Meloche, S (2015-05-12)
Created
Rothfels, K (2015-04-27)
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