Reactome | GGA1 [endosome membrane]

GGA1 [endosome membrane]

Stable Identifier

R-HSA-5692930

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endosome membrane

Synonyms

ADP-ribosylation factor-binding protein GGA1, GGA1_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9UJY5 GGA1

Gene Names

GGA1

Chain

chain:1-639

Reference Genes

BioGPS Gene:26088 GGA1

COSMIC (genes):GGA1 GGA1

CTD Gene:26088 GGA1

dbSNP Gene:26088 GGA1

ENSEMBL:ENSG00000100083 GGA1

ENSEMBL_homo_sapiens_GENE:ENSG00000100083.19 GGA1

HGNC:17842 GGA1

KEGG Gene (Homo sapiens):26088 GGA1

Monarch:26088 GGA1

NCBI Gene:26088 GGA1

OMIM:606004 GGA1

UCSC:Q9UJY5 GGA1

Reference Transcript

Other Identifiers

11736096_a_at

11736097_a_at

16929782

218114_3p_at

218114_PM_at

218114_at

26088

3944780

3944781

3944782

3944783

3944784

3944791

3944792

3944793

3944797

3944798

3944799

3944800

3944801

3944802

3944805

3944809

3944810

3944814

3944815

3944816

3944818

3944820

3944821

3944822

3944823

3944825

45572_PM_s_at

45572_s_at

50277_PM_at

50277_at

8072825

A_23_P132294

A_33_P3305915

GE61116

GO:0003674

GO:0005515

GO:0005634

GO:0005654

GO:0005768

GO:0005769

GO:0005794

GO:0005802

GO:0005829

GO:0006886

GO:0006893

GO:0008104

GO:0008289

GO:0010008

GO:0015031

GO:0016020

GO:0016192

GO:0030163

GO:0031267

GO:0031410

GO:0031901

GO:0032991

GO:0034394

GO:0035091

GO:0042147

GO:0043001

GO:0043130

GO:0043226

GO:0043231

GO:0045732

GO:0051641

GO:0072659

GO:0097708

GO:1903441

HMNXSV003019050

ILMN_1658175

ILMN_1681668

PH_hs_0033137

TC22000283.hg

g9558728_3p_at

g9558728_3p_s_at

Participates

as a member of

GGA1,2,3 [endosome membrane] (Homo sapiens)

Other forms of this molecule

GGA1 [early endosome membrane]

Cross References

RefSeq

XP_006724292.1, XP_016884251.1, XP_005261574.1, NP_001166158.1, XP_011528424.1, NP_001001560.1, XP_016884250.1, XP_005261577.1, NP_001166159.1, XP_016884249.1, NP_037497.1

OpenTargets

ENSG00000100083

GeneCards

Q9UJY5

HPA

ENSG00000100083-GGA1

Ensembl

ENSP00000341344, ENST00000325180, ENST00000406772, ENST00000381756, ENSP00000321288, ENSP00000385287, ENSP00000371175, ENST00000343632, ENSG00000100083

PRO

Q9UJY5

Pharos - Targets

Q9UJY5

HMDB Protein

HMDBP08420

PDB

1PY1, 1NA8, 3G2T, 1OXZ, 1X79, 1UJK, 2DWY, 3G2S, 3G2W, 1O3X, 2DWX, 1NAF, 1JWG, 1UJJ, 3G2V, 1JWF, 3G2U, 1OM9, 1NWM, 1J2J

Interactors (13)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q92673 SORL1	2	SORL1 [endosome membrane] (R-HSA-8871475) SORL1 [Golgi membrane] (R-HSA-8871510)	0.744	5
UniProt:P56817 BACE1	8	BACE1 [endoplasmic reticulum lumen] (R-HSA-6783326) 7K-BACE1 [endoplasmic reticulum lumen] (R-HSA-5693006) BACE1(22-45) [Golgi-associated vesicle lumen] (R-HSA-5693069) 7K-BACE1 [Golgi-associated vesicle lumen] (R-HSA-5693095) 7K-BACE1(46-501) [Golgi-associated vesicle lumen] (R-HSA-5693106) BACE1(46-501) [Golgi-associated vesicle lumen] (R-HSA-5693105) BACE1(46-501) [plasma membrane] (R-HSA-5692933) BACE1 [endosome membrane] (R-HSA-5692942)	0.668	4
UniProt:P0CG47 UBB	20	UBB(77-152) [endocytic vesicle membrane] (R-HSA-939253) UBB(1-76) [endocytic vesicle membrane] (R-HSA-939231) UBB(153-228) [endocytic vesicle membrane] (R-HSA-939171) Ub-33-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783023) Ub-109-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6783008) Ub-185-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783046) Ub-215-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783002) Ub-63-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783148) Ub-139-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6783012) Ub-158-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783162) Ub-6-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783014) Ub-82-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6783015) Ub-163-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783025) Ub-87-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6782998) Ub-11-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783109) Ub-124-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6783131) Ub-200-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783100) Ub-48-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783165) Ub-181-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783160) Ub-29-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783070)	0.581	3
UniProt:P35579 MYH9	3	MYH9 [cytosol] (R-HSA-419173) MYH9(2-1644)-ALK(1067-1620) fusion [cytosol] (R-HSA-9715280) MYH9(2-1644)-p-7Y-ALK(1067-1620) fusion [cytosol] (R-HSA-9715279)	0.558	2
UniProt:Q9NYZ3 GTSE1	4	GTSE1 [cytosol] (R-HSA-8852264) p-S435-GTSE1 [cytosol] (R-HSA-8852316) p-S435-GTSE1 [nucleoplasm] (R-HSA-8852332) p-T513,T526-GTSE1 [cytosol] (R-HSA-8852308)	0.544	2
UniProt:P05412 JUN	4	p-S63,S73-JUN [cytosol] (R-HSA-8868682) JUN [nucleoplasm] (R-HSA-450250) p-S63,S73-JUN [nucleoplasm] (R-HSA-450237) JUN [cytosol] (R-HSA-168194)	0.544	2
UniProt:P84080	2	ARF1 [cytosol] (R-BTA-200826) ARF1 [Golgi membrane] (R-BTA-199971)	0.527	2
UniProt:Q14186 TFDP1	1	TFDP1 [nucleoplasm] (R-HSA-68652)	0.527	2
UniProt:Q9Y3P9 RABGAP1	1	RABGAP1 [cytosol] (R-HSA-8854144)	0.527	3
UniProt:Q96A65 EXOC4	2	EXOC4 [plasma membrane] (R-HSA-264989) EXOC4 [cytosol] (R-HSA-5623381)	0.527	3
UniProt:P51790 CLCN3	1	CLCN3 [late endosome membrane] (R-HSA-2671918)	0.527	3
UniProt:P13569 CFTR	17	PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.519	6
UniProt:Q9NZ52 GGA3	3	GGA3 [endosome membrane] (R-HSA-5692936) GGA3 [recycling endosome membrane] (R-HSA-8875655) GGA3 [early endosome membrane] (R-HSA-8854137)	0.508	4

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