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GGA2 [endosome membrane]
Stable Identifier
R-HSA-5692937
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endosome membrane
Synonyms
ADP-ribosylation factor-binding protein GGA2, GGA2_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Amyloid fiber formation (Homo sapiens)
BACE1 binds GGA1,2,3 (Homo sapiens)
BACE1:GGA1,2,3 [plasma membrane] (Homo sapiens)
GGA1,2,3 [endosome membrane] (Homo sapiens)
GGA2 [endosome membrane] (Homo sapiens)
GGA1,2,3 [endosome membrane] (Homo sapiens)
GGA2 [endosome membrane] (Homo sapiens)
BACE1:GGA1,2,3 translocates from plasma membrane to endosome (Homo sapiens)
BACE1:GGA1,2,3 [plasma membrane] (Homo sapiens)
GGA1,2,3 [endosome membrane] (Homo sapiens)
GGA2 [endosome membrane] (Homo sapiens)
GGA1,2,3 [endosome membrane] (Homo sapiens)
GGA2 [endosome membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9UJY4 GGA2
Gene Names
GGA2, KIAA1080
Chain
chain:1-613
Reference Genes
BioGPS Gene:23062 GGA2
COSMIC (genes):GGA2 GGA2
CTD Gene:23062 GGA2
dbSNP Gene:23062 GGA2
ENSEMBL:ENSG00000103365 GGA2
ENSEMBL_homo_sapiens_GENE:ENSG00000103365.15 GGA2
HGNC:16064 GGA2
KEGG Gene (Homo sapiens):23062 GGA2
Monarch:23062 GGA2
NCBI Gene:23062 GGA2
OMIM:606005 GGA2
UCSC:Q9UJY4 GGA2
Reference Transcript
RefSeq:NM_015044.4 GGA2
Other Identifiers
11722372_a_at
11722373_a_at
11722374_a_at
11722375_a_at
16825057
208913_PM_at
208913_at
208914_PM_at
208914_at
208915_PM_s_at
208915_s_at
210658_PM_s_at
210658_s_at
213772_PM_s_at
213772_s_at
214190_PM_x_at
214190_x_at
23062
3685184
3685185
3685186
3685187
3685188
3685189
3685190
3685191
3685192
3685193
3685194
3685195
3685196
3685197
3685198
3685200
3685201
3685204
3685205
3685206
3685210
3685211
3685213
3685215
3685216
3685218
3685219
3685222
3685223
3685228
3685230
3685232
3685234
3685236
3685241
3685242
40278_at
8000284
86257_at
A_23_P163732
A_24_P416257
A_32_P106117
GE79376
GO:0005515
GO:0005768
GO:0005794
GO:0005802
GO:0006886
GO:0006893
GO:0008289
GO:0010008
GO:0015031
GO:0016020
GO:0016192
GO:0030136
GO:0031267
GO:0031410
GO:0031901
GO:0034394
GO:0035091
GO:0043001
GO:0043130
GO:0043226
GO:0051641
GO:0072659
GO:0097708
HMNXSV003008326
Hs.155546.0.S3_3p_at
Hs.155546.0.S4_3p_at
Hs.155546.2.S1_3p_a_at
Hs.155546.4.S1_3p_a_at
ILMN_1686152
PH_hs_0022504
TC16000963.hg
g12653040_3p_a_at
g6179913_3p_a_at
Participates
as a member of
GGA1,2,3 [endosome membrane] (Homo sapiens)
Other forms of this molecule
GGA2 [early endosome membrane]
Cross References
RefSeq
NP_055859.1
OpenTargets
ENSG00000103365
GeneCards
Q9UJY4
HPA
ENSG00000103365-GGA2
Ensembl
ENST00000309859
,
ENSG00000103365
,
ENSP00000311962
PRO
Q9UJY4
Pharos - Targets
Q9UJY4
PDB
1MHQ
HMDB Protein
HMDBP08421
Interactors (6)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q92673 SORL1
2
SORL1 [endosome membrane]
(R-HSA-8871475)
SORL1 [Golgi membrane]
(R-HSA-8871510)
0.774
6
UniProt:Q9Y316 MEMO1
1
MEMO1 [cytosol]
(R-HSA-6785630)
0.556
3
UniProt:P56817 BACE1
8
BACE1 [endoplasmic reticulum lumen]
(R-HSA-6783326)
7K-BACE1 [endoplasmic reticulum lumen]
(R-HSA-5693006)
BACE1(22-45) [Golgi-associated vesicle lumen]
(R-HSA-5693069)
7K-BACE1 [Golgi-associated vesicle lumen]
(R-HSA-5693095)
7K-BACE1(46-501) [Golgi-associated vesicle lumen]
(R-HSA-5693106)
BACE1(46-501) [Golgi-associated vesicle lumen]
(R-HSA-5693105)
BACE1(46-501) [plasma membrane]
(R-HSA-5692933)
BACE1 [endosome membrane]
(R-HSA-5692942)
0.544
2
UniProt:P84080
2
ARF1 [cytosol]
(R-BTA-200826)
ARF1 [Golgi membrane]
(R-BTA-199971)
0.527
2
UniProt:Q9NZ52 GGA3
3
GGA3 [endosome membrane]
(R-HSA-5692936)
GGA3 [recycling endosome membrane]
(R-HSA-8875655)
GGA3 [early endosome membrane]
(R-HSA-8854137)
0.508
3
UniProt:Q08379 GOLGA2
3
p-S37-GOLGA2 [Golgi membrane]
(R-HSA-2172179)
GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-2167933)
GOLGA2 [Golgi membrane]
(R-HSA-6808764)
0.488
2
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