Reactome | STAMBP [cytosol]

STAMBP [cytosol]

Stable Identifier

R-HSA-5693063

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

STAM-binding protein, STABP_HUMAN

Locations in the PathwayBrowser for interactor UniProt:Q9H444 CHMP4B

Expand all

External Reference Information

External Reference

UniProt:O95630 STAMBP

Gene Names

STAMBP, AMSH

Chain

chain:1-424

Reference Genes

BioGPS Gene:10617 STAMBP

COSMIC (genes):STAMBP STAMBP

CTD Gene:10617 STAMBP

dbSNP Gene:10617 STAMBP

ENSEMBL:ENSG00000124356 STAMBP

HGNC:16950 STAMBP

Monarch:10617 STAMBP

NCBI Gene:10617 STAMBP

OMIM:606247 STAMBP

UCSC:O95630 STAMBP

Reference Transcript

Other Identifiers

10617

11716113_a_at

16881569

202811_PM_at

202811_at

227515_PM_at

227515_at

235361_PM_at

235361_at

2488960

2488961

2488962

2488963

2488964

2488965

2488966

2488967

2488968

2488974

2488975

2488976

2488977

2488978

2488979

2488980

2488981

2488982

2488983

2488986

2488987

2488988

2488989

2488990

2488991

2488992

2488993

2488994

2488995

2488996

2488997

2488998

2488999

2489000

2489001

2489002

2489003

2489004

2489005

2489006

39391_at

79177_at

8042772

85146_at

ADDON000673.hg

ADDON001283.hg

A_14_P106056

A_21_P0014839

A_23_P28559

A_24_P585747

A_33_P3364696

GE61477

GE88252

GO:0000281

GO:0000910

GO:0003824

GO:0005515

GO:0005634

GO:0005654

GO:0005737

GO:0005768

GO:0005769

GO:0005829

GO:0005886

GO:0006508

GO:0007259

GO:0008233

GO:0008237

GO:0008284

GO:0012501

GO:0016020

GO:0016579

GO:0016787

GO:0019904

GO:0031410

GO:0032154

GO:0043226

GO:0046580

GO:0046872

GO:0051898

GO:0061578

GO:0070062

GO:0070536

GO:0101005

GO:0110088

GO:0110091

GO:0140096

GO:0140492

HMNXSV003018593

HMNXSV003035171

HMNXSV003036405

Hs.183070.0.A1_3p_at

Hs.288029.0.S1_3p_at

ILMN_1665521

ILMN_1739253

ILMN_2391355

PH_hs_0001186

PH_hs_0039429

TC02000447.hg

g5453544_3p_at

p25160

Participates

as a component of

STAMBP:STAM [cytosol] (Homo sapiens)

as an input of

STAMBP binds STAM (Homo sapiens)

Inferred To

Q9VA71 [cytosol] (Drosophila melanogaster)

stambp [cytosol] (Xenopus tropicalis)

STAMBP [cytosol] (Bos taurus)

STAMBP [cytosol] (Canis familiaris)

STAMBP [cytosol] (Gallus gallus)

STAMBP [cytosol] (Mus musculus)

STAMBP [cytosol] (Rattus norvegicus)

STAMBP [cytosol] (Schizosaccharomyces pombe)

STAMBP [cytosol] (Sus scrofa)

Cross References

OpenTargets

ENSG00000124356

ENSEMBL

ENSP00000507092, ENSP00000507014, ENSP00000506865, ENSP00000507658, ENSP00000507054, ENST00000339566, ENSP00000344742, ENST00000684095, ENST00000682351, ENST00000684312, ENSP00000506958, ENST00000682558, ENST00000682379, ENSP00000507864, ENSP00000507081, ENSP00000377636, ENST00000682847, ENST00000432295, ENST00000394073, ENSP00000377633, ENST00000394070, ENST00000683518, ENST00000683818, ENSP00000506833, ENSP00000413874, ENSP00000386548, ENST00000409707, ENST00000683036, ENST00000684585, ENSP00000507639, ENST00000683317, ENSP00000506845

HPA

ENSG00000124356-STAMBP

PRO

O95630

Pharos - Targets

O95630

GlyGen

O95630

Orphanet

STAMBP

HMDB Protein

HMDBP10111

PDB

5IXF, 3RZU, 3RZV, 2XZE

Interactors (35)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9Y3E7 CHMP3	2	CHMP3 [endosome membrane] (R-HSA-9631191) CHMP3 [cytosol] (R-HSA-917722)	0.964	27
UniProt:Q7LBR1 CHM1B			0.961	21
UniProt:P62993 GRB2	1	GRB2 [cytosol] (R-HSA-8983328)	0.926	10
UniProt:O75886 STAM2	2	Ub-STAM2 [cytosol] (R-HSA-6782781) STAM2 [cytosol] (R-HSA-182965)	0.839	9
UniProt:Q9HD42 CHMP1A	1	CHMP1A [cytosol] (R-HSA-917721)	0.835	8
UniProt:O75791 GRAP2	1	GRAP2 [cytosol] (R-HSA-202367)	0.807	6
UniProt:Q92783 STAM	1	STAM [cytosol] (R-HSA-182925)	0.771	7
UniProt:Q9Y3E7-1 CHMP3			0.74	6
UniProt:Q9Y3C5 RNF11			0.703	5
UniProt:P0CG47 UBB	20	UBB(77-152) [endocytic vesicle membrane] (R-HSA-939253) UBB(1-76) [endocytic vesicle membrane] (R-HSA-939231) UBB(153-228) [endocytic vesicle membrane] (R-HSA-939171) Ub-33-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783023) Ub-109-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6783008) Ub-185-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783046) Ub-215-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783002) Ub-63-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783148) Ub-139-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6783012) Ub-158-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783162) Ub-6-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783014) Ub-82-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6783015) Ub-163-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783025) Ub-87-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6782998) Ub-11-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783109) Ub-124-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6783131) Ub-200-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783100) Ub-48-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783165) Ub-181-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783160) Ub-29-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783070)	0.683	4
UniProt:O43633 CHMP2A	2	CHMP2A [cytosol] (R-HSA-917734) CHMP2A [endosome membrane] (R-HSA-9631172)	0.659	3
UniProt:Q9NSY1 BMP2K			0.659	3
UniProt:O00443 PIK3C2A	3	PIK3C2A [cytosol] (R-HSA-1604624) PIK3C2A [cytoplasmic vesicle membrane] (R-HSA-432683) PIK3C2A [Golgi membrane] (R-HSA-432679)	0.643	4
UniProt:Q9NYZ3 GTSE1	4	GTSE1 [cytosol] (R-HSA-8852264) p-S435-GTSE1 [cytosol] (R-HSA-8852316) p-S435-GTSE1 [nucleoplasm] (R-HSA-8852332) p-T513,T526-GTSE1 [cytosol] (R-HSA-8852308)	0.643	3
UniProt:Q15645 PCH2			0.621	4
UniProt:Q9NZZ3 CHMP5	1	CHMP5 [cytosol] (R-HSA-917694)	0.573	2
UniProt:Q8IVW4 CDKL3			0.564	2
UniProt:Q13148 TADBP			0.556	3
UniProt:P48643 CCT5	1	CCT5 [cytosol] (R-HSA-390447)	0.556	3
UniProt:Q8WXH2 JPH3			0.556	3
UniProt:P54253 ATX1			0.556	6
UniProt:O60260-5 PRKN			0.556	3
UniProt:P31941 APOBEC3A	1	APOBEC3A [nucleoplasm] (R-HSA-8875001)	0.556	3
UniProt:Q9BY43 CHMP4A	2	CHMP4A [endosome membrane] (R-HSA-9631184) CHMP4A [cytosol] (R-HSA-917733)	0.553	2
UniProt:Q9H444 CHMP4B	2	CHMP4B [cytosol] (R-HSA-917708) CHMP4B [endosome membrane] (R-HSA-9631202)	0.553	3
UniProt:Q14677 CLINT1	1	CLINT1 [cytosol] (R-HSA-429811)	0.527	2
UniProt:Q8N5S1 S2541			0.527	2
UniProt:Q15311 RALBP1	1	RALBP1 [cytosol] (R-HSA-195194)	0.527	2
UniProt:O14976 GAK	3	GAK [cytosol] (R-HSA-8868619) GAK [Golgi membrane] (R-HSA-434340) GAK [cytoplasmic vesicle membrane] (R-HSA-434203)	0.527	2
UniProt:Q9UEU0 VTI1B	2	VTI1B [extracellular region] (R-HSA-8862983) VTI1B [platelet alpha granule lumen] (R-HSA-8862964)	0.527	2
UniProt:Q96FJ0 STAMBPL1	1	STAMBPL1 [cytosol] (R-HSA-6783264)	0.527	2
UniProt:Q8IXM7 CMA1C			0.527	2
UniProt:Q96NR8 RDH12	6	RDH12 A126V [photoreceptor inner segment membrane] (R-HSA-2471753) RDH12 Q189* [photoreceptor inner segment membrane] (R-HSA-2471667) RDH12 Y226C [photoreceptor inner segment membrane] (R-HSA-2471697) RDH12 H151N [photoreceptor inner segment membrane] (R-HSA-2471751) RDH12 Ala269Glyfs*2 [photoreceptor inner segment membrane] (R-HSA-2471748) RDH12 [photoreceptor inner segment membrane] (R-HSA-2464787)	0.527	2
UniProt:O43541-2 SMAD6			0.508	2
UniProt:O35182	1	SMAD6 [cytosol] (R-MMU-3006350)	0.463	2

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