Reactome | STAMBPL1 is a deubiquitinase

STAMBPL1 is a deubiquitinase

Stable Identifier

R-HSA-5696547

Type

Reaction [omitted]

Species

Homo sapiens

Compartment

cytosol

ReviewStatus

5/5

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STAMBPL1 (AMSH-LP) has Lys-63 deubiquitinase activity (Sato et al. 2008) and positively regulates TGF-beta signaling (Ibarolla et al. 2004) but unlike STAMBP (AMSH1) it does not bind STAM (Kikuchi et al. 2003).

Literature References

PubMed ID	Title	Journal	Year
18758443	Structural basis for specific cleavage of Lys 63-linked polyubiquitin chains Yoshikawa, A, Yamashita, M, Komada, M, Iwai, K, Nureki, O, Ookata, K, Yamagata, A, Sato, Y, Fukai, S, Mimura, H	Nature	2008