Reactome | POP1 [nucleoplasm]

POP1 [nucleoplasm]

Stable Identifier

R-HSA-5696802

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Ribonucleases P/MRP protein subunit POP1, POP1_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q99575 POP1

Gene Names

POP1, KIAA0061

Chain

chain:1-1024

Reference Genes

BioGPS Gene:10940 POP1

COSMIC (genes):POP1 POP1

CTD Gene:10940 POP1

dbSNP Gene:10940 POP1

ENSEMBL:ENSG00000104356 POP1

HGNC:30129 POP1

Monarch:10940 POP1

NCBI Gene:10940 POP1

OMIM:602486 POP1

UCSC:Q99575 POP1

Reference Transcript

Other Identifiers

10940

11723138_at

11723139_at

17071265

213449_PM_at

213449_at

3108666

3108668

3108669

3108671

3108672

3108673

3108674

3108675

3108676

3108677

3108678

3108679

3108680

3108681

3108687

3108688

3108689

3108691

3108692

3108693

3108694

3108696

3108697

3108698

3108699

3108700

3108701

3108702

38513_at

8147548

A_14_P103244

A_14_P134024

A_23_P341275

A_24_P943000

D31765_at

GE57164

GO:0000172

GO:0001682

GO:0003723

GO:0003824

GO:0004526

GO:0005515

GO:0005615

GO:0005634

GO:0005654

GO:0005655

GO:0005730

GO:0006399

GO:0008033

GO:0016078

GO:0016787

GO:0030681

GO:0033204

GO:0043226

GO:0140098

HMNXSV003014678

Hs.170114.0.S1_3p_at

ILMN_1768273

PH_hs_0010153

TC08000602.hg

Participates

as a component of

RNase P [nucleoplasm] (Homo sapiens)

Cross References

ENSEMBL

ENSP00000385787, ENSP00000339529, ENST00000349693, ENST00000401707

OpenTargets

ENSG00000104356

HPA

ENSG00000104356-POP1

PRO

Q99575

Pharos - Targets

Q99575

GlyGen

Q99575

Orphanet

POP1

PDB

6AHR, 6AHU

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q15646 OASL	1	OASL [cytosol] (R-HSA-1015678)	0.527	2
UniProt:Q9H9Z2 LIN28A	1	LIN28A [cytosol] (R-HSA-500391)	0.527	2
UniProt:Q9NR30 DDX21	1	DDX21 [nucleoplasm] (R-HSA-5250652)	0.527	2
UniProt:P03372 ESR1	10	ESR1 [cytosol] (R-HSA-9020968) ESR1 [nucleoplasm] (R-HSA-446168) Me260-PalmS-ESR1 [plasma membrane] (R-HSA-9637788) PalmS-ESR1 [plasma membrane] (R-HSA-9021057) PalmS-ESR1 [cytosol] (R-HSA-9020974) Me260-ESR1 [cytosol] (R-HSA-9632177) p-S167-ESR1 [cytosol] (R-HSA-9841254) p-S167-ESR1 [nucleoplasm] (R-HSA-9841867) monoSUMO1-5K-ESR1 [nucleoplasm] (R-HSA-4090302) p-S118-ESR1 [nucleoplasm] (R-HSA-9024210)	0.527	3
UniProt:P06748 NPM1	11	NPM1 [cytosol] (R-HSA-3008211) p-S4-NPM1 [cytosol] (R-HSA-6801679) NPM1 [nucleoplasm] (R-HSA-606320) NPM1 [granular component] (R-HSA-9017702) NPM1(1-117)-ALK(1058-1620) fusion [cytosol] (R-HSA-9699834) NPM1(1-117)-p-7Y-ALK(1058-1620) fusion [cytosol] (R-HSA-9699861) NPM1(1-117)-ALK(1068-1620) fusion [cytosol] (R-HSA-9730697) NPM1(1-117)-p-7Y-ALK(1068-1620) fusion [cytosol] (R-HSA-9730703) NPM1(1-117)-p-7Y-ALK(1058-1620) fusion [nucleoplasm] (R-HSA-9725010) polySUMO2,3-K263-NPM1 [nucleoplasm] (R-HSA-4086056) monoSUMO1-K263-NPM1 [nucleoplasm] (R-HSA-4086039)	0.527	2

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