Reactome | POP1 [nucleoplasm]

POP1 [nucleoplasm]

Stable Identifier

R-HSA-5696802

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Ribonucleases P/MRP protein subunit POP1, POP1_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q99575 POP1

Gene Names

POP1, KIAA0061

Chain

chain:1-1024

Reference Genes

BioGPS Gene:10940 POP1

COSMIC (genes):POP1 POP1

CTD Gene:10940 POP1

dbSNP Gene:10940 POP1

ENSEMBL:ENSG00000104356 POP1

HGNC:30129 POP1

KEGG:hsa:10940 POP1

Monarch:10940 POP1

NCBI Gene:10940 POP1

OMIM:602486 POP1

UCSC:Q99575 POP1

Reference Transcript

Other Identifiers

10940

11723138_at

11723139_at

17071265

213449_PM_at

213449_at

3108666

3108667

3108668

3108669

3108671

3108672

3108673

3108674

3108675

3108676

3108677

3108678

3108679

3108680

3108681

3108687

3108688

3108689

3108691

3108692

3108693

3108694

3108696

3108697

3108698

3108699

3108700

3108701

3108702

38513_at

8147548

A_14_P103244

A_14_P134024

A_23_P341275

A_24_P943000

D31765_at

GE57164

GO:0000172

GO:0001682

GO:0003723

GO:0003824

GO:0004526

GO:0005515

GO:0005615

GO:0005634

GO:0005654

GO:0005655

GO:0005730

GO:0006399

GO:0008033

GO:0016078

GO:0016787

GO:0030681

GO:0033204

GO:0140098

HMNXSV003014678

Hs.170114.0.S1_3p_at

ILMN_1768273

PH_hs_0010153

TC08000602.hg

Participates

as a component of

RNase P [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_001139332.1, NP_001139333.1, NP_055844.2

ENSEMBL

ENSG00000104356, ENSP00000339529, ENST00000349693, ENST00000401707, ENSP00000385787

OpenTargets

ENSG00000104356

GeneCards

POP1

HPA

ENSG00000104356-POP1

PRO

Q99575

Pharos - Targets

Q99575

GlyGen

Q99575

Orphanet

POP1

PDB

6AHR, 6AHU

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9NR30 DDX21	1	DDX21 [nucleoplasm] (R-HSA-5250652)	0.527	2
UniProt:Q9H9Z2 LIN28A	1	LIN28A [cytosol] (R-HSA-500391)	0.527	2
UniProt:Q15646 OASL	1	OASL [cytosol] (R-HSA-1015678)	0.527	2
UniProt:P06748 NPM1	11	NPM1 [cytosol] (R-HSA-3008211) p-S4-NPM1 [cytosol] (R-HSA-6801679) NPM1 [nucleoplasm] (R-HSA-606320) NPM1 [granular component] (R-HSA-9017702) NPM1(1-117)-ALK(1058-1620) fusion [cytosol] (R-HSA-9699834) NPM1(1-117)-p-7Y-ALK(1058-1620) fusion [cytosol] (R-HSA-9699861) NPM1(1-117)-ALK(1068-1620) fusion [cytosol] (R-HSA-9730697) NPM1(1-117)-p-7Y-ALK(1068-1620) fusion [cytosol] (R-HSA-9730703) NPM1(1-117)-p-7Y-ALK(1058-1620) fusion [nucleoplasm] (R-HSA-9725010) polySUMO2,3-K263-NPM1 [nucleoplasm] (R-HSA-4086056) monoSUMO1-K263-NPM1 [nucleoplasm] (R-HSA-4086039)	0.527	2
UniProt:P03372 ESR1	10	ESR1 [cytosol] (R-HSA-9020968) ESR1 [nucleoplasm] (R-HSA-446168) PalmS-ESR1 [cytosol] (R-HSA-9020974) PalmS-ESR1 [plasma membrane] (R-HSA-9021057) Me260-PalmS-ESR1 [plasma membrane] (R-HSA-9637788) Me260-ESR1 [cytosol] (R-HSA-9632177) p-S167-ESR1 [cytosol] (R-HSA-9841254) p-S167-ESR1 [nucleoplasm] (R-HSA-9841867) monoSUMO1-5K-ESR1 [nucleoplasm] (R-HSA-4090302) p-S118-ESR1 [nucleoplasm] (R-HSA-9024210)	0.527	3

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