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TK2 [mitochondrial matrix]
Stable Identifier
R-HSA-58100
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
mitochondrial matrix
Synonyms
thymidine kinase 2, mitochondrial, Mt-TK
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of nucleotides (Homo sapiens)
Nucleotide salvage (Homo sapiens)
Pyrimidine salvage (Homo sapiens)
deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] (Homo sapiens)
TK2 [mitochondrial matrix] (Homo sapiens)
External Reference Information
External Reference
UniProt:O00142 TK2
Gene Names
TK2
Chain
transit peptide:1-33, chain:34-265
Reference Genes
BioGPS Gene:7084 TK2
COSMIC (genes):TK2 TK2
CTD Gene:7084 TK2
dbSNP Gene:7084 TK2
ENSEMBL:ENSG00000166548 TK2
ENSEMBL_homo_sapiens_GENE:ENSG00000166548.17 TK2
HGNC:11831 TK2
KEGG Gene (Homo sapiens):7084 TK2
Monarch:7084 TK2
NCBI Gene:7084 TK2
OMIM:188250 TK2
UCSC:O00142 TK2
Reference Transcript
RefSeq:NM_001172643.1 TK2
RefSeq:NM_001172644.1 TK2
RefSeq:NM_001271935.1 TK2
RefSeq:NM_001272050.1 TK2
RefSeq:NM_004614.4 TK2
Other Identifiers
11727557_s_at
11727558_a_at
11749959_a_at
144_at
16827103
16827120
204227_PM_s_at
204227_s_at
204276_PM_at
204276_at
204277_PM_s_at
204277_s_at
240300_PM_at
240300_at
2877097
3695104
3695106
3695108
3695109
3695110
3695111
3695112
3695113
3695114
3695115
3695117
3695118
3695122
3695123
3695124
3695125
3695127
3695128
3695129
3695130
3695131
3695132
3695133
3695134
3695135
3695136
7084
8001818
82680_at
A_23_P351679
A_24_P219324
A_33_P3392537
GE61028
GE807940
GO:0000166
GO:0003824
GO:0004137
GO:0004797
GO:0005524
GO:0005737
GO:0005739
GO:0005759
GO:0006139
GO:0009157
GO:0009165
GO:0016301
GO:0016310
GO:0016740
GO:0019136
GO:0019206
GO:0043097
GO:0043226
GO:0046092
GO:0046104
GO:0055086
GO:0071897
GO:1901135
HMNXSV003037777
Hs.144917.0.A1_3p_at
Hs.274701.0.S2_3p_at
ILMN_1766814
PH_hs_0014182
TC16001169.hg
TC16001927.hg
U80628_at
g10281329_3p_a_at
Inferred To
BEAN1 [mitochondrial matrix]
(Bos taurus)
tk2 [mitochondrial matrix]
(Xenopus tropicalis)
Tk2 [mitochondrial matrix]
(Rattus norvegicus)
TK2 [mitochondrial matrix]
(Canis familiaris)
TK2 [mitochondrial matrix]
(Drosophila melanogaster)
TK2 [mitochondrial matrix]
(Gallus gallus)
TK2 [mitochondrial matrix]
(Mus musculus)
TK2 [mitochondrial matrix]
(Sus scrofa)
Cross References
RefSeq
NP_001258864.1
,
NP_001258979.1
,
NP_004605.4
,
NP_001166114.1
,
NP_001166115.1
OpenTargets
ENSG00000166548
GeneCards
O00142
HPA
ENSG00000166548-TK2
ZINC target
O00142
Ensembl
ENSP00000503331
,
ENSP00000503472
,
ENSP00000407469
,
ENST00000527800
,
ENST00000544898
,
ENSP00000502950
,
ENSP00000414334
,
ENST00000677715
,
ENSP00000504648
,
ENST00000678015
,
ENST00000525974
,
ENST00000677555
,
ENSP00000463560
,
ENSP00000502959
,
ENST00000563369
,
ENST00000678297
,
ENST00000545043
,
ENST00000677420
,
ENSP00000434594
,
ENST00000417693
,
ENSG00000166548
,
ENST00000451102
,
ENSP00000433770
,
ENSP00000440898
,
ENSP00000438143
PRO
O00142
Pharos - Targets
O00142
Orphanet
15623
HMDB Protein
HMDBP03815
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