XRCC6 [nucleoplasm]

Stable Identifier
R-HSA-58272
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
ATP-dependent DNA helicase II, 70 kDa subunit, Lupus Ku autoantigen protein p70, Ku70, 70 kDa subunit of Ku antigen, Thyroid-lupus autoantigen, TLAA, CTC box binding factor 75 kDa subunit, CTCBF, CTC75
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:P12956 XRCC6
Gene Names
XRCC6, G22P1
Chain
initiator methionine:, chain:2-609
Reference Genes
BioGPS Gene:2547 XRCC6
COSMIC (genes):XRCC6 XRCC6
CTD Gene:2547 XRCC6
dbSNP Gene:2547 XRCC6
ENSEMBL:ENSG00000196419 XRCC6
ENSEMBL_homo_sapiens_GENE:ENSG00000196419.13 XRCC6
HGNC:4055 XRCC6
KEGG Gene (Homo sapiens):2547 XRCC6
Monarch:2547 XRCC6
NCBI Gene:2547 XRCC6
OMIM:152690 XRCC6
UCSC:P12956 XRCC6
Reference Transcript
Other Identifiers
11730714_s_at
11754932_x_at
16930678
200792_PM_at
200792_at
2547
32766_at
3300572
3946972
3946973
3946974
3946975
3946976
3946978
3946981
3946982
3946984
3946987
3946989
3946990
3946993
3946994
3946995
3946997
3946998
3946999
4025651
4025653
4025659
4025661
4025663
8073457
A_23_P120942
GE61354
GE81028
GO:0000166
GO:0000723
GO:0000725
GO:0000781
GO:0000783
GO:0000976
GO:0002218
GO:0002376
GO:0003677
GO:0003678
GO:0003684
GO:0003690
GO:0003691
GO:0003723
GO:0003824
GO:0004386
GO:0005515
GO:0005524
GO:0005576
GO:0005634
GO:0005654
GO:0005667
GO:0005694
GO:0005730
GO:0005829
GO:0005958
GO:0006266
GO:0006281
GO:0006303
GO:0006310
GO:0006351
GO:0006355
GO:0006974
GO:0008094
GO:0008152
GO:0010558
GO:0016020
GO:0016787
GO:0016829
GO:0016887
GO:0030154
GO:0030332
GO:0031410
GO:0032200
GO:0032508
GO:0032991
GO:0032993
GO:0034774
GO:0036211
GO:0042162
GO:0043226
GO:0043231
GO:0043564
GO:0044877
GO:0045027
GO:0045087
GO:0045621
GO:0045860
GO:0045892
GO:0045893
GO:0045944
GO:0048660
GO:0048856
GO:0051575
GO:0070418
GO:0070419
GO:0071475
GO:0071480
GO:0071481
GO:0097110
GO:0097680
GO:0098542
GO:0140097
GO:0140657
GO:1904813
HMNXSV003043756
ILMN_1743097
ILMN_2166506
J04611_at
PH_hs_0022800
TC22000339.hg
g4503840_3p_at
Participates
as a component of
Other forms of this molecule
XRCC6 [cytosol]
XRCC6 [secretory granule lumen]
XRCC6 [extracellular region]
XRCC6 [ficolin-1-rich granule lumen]
Inferred To
pku70 [nucleoplasm] (Schizosaccharomyces pombe)
Irbp [nucleoplasm] (Drosophila melanogaster)
XRCC6 [nucleoplasm] (Bos taurus)
XRCC6 [nucleoplasm] (Canis familiaris)
XRCC6 [nucleoplasm] (Gallus gallus)
XRCC6 [nucleoplasm] (Sus scrofa)
xrcc6 [nucleoplasm] (Xenopus tropicalis)
ku70 [nucleoplasm] (Dictyostelium discoideum)
Xrcc6 [nucleoplasm] (Mus musculus)
Xrcc6 [nucleoplasm] (Rattus norvegicus)
YKU70 [nucleoplasm] (Saccharomyces cerevisiae)
Cross References
RefSeq
OpenTargets
HPA
GeneCards
Ensembl
PRO
Pharos - Targets
PDB
Interactors (16)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q14191 WRN  2 0.897 10
 UniProt:P78527 PRKDC  4 0.896 8
 UniProt:P09874 PARP1  4 0.853 9
 UniProt:P42858 HTT  1 0.703 21
 UniProt:Q96EB6 SIRT1  1 0.667 7
 UniProt:Q13426 XRCC4  2 0.656 3
 UniProt:Q01831 XPC  5 0.643 3
 UniProt:P13569 CFTR  17 0.615 13
 UniProt:O76024 WFS1  3 0.556 3
 UniProt:P16104 H2AFX  7 0.527 2
 UniProt:Q08945 SSRP1  1 0.527 2
 UniProt:Q9Y5B9 SUPT16H  1 0.527 2
 UniProt:P83916 CBX1  1 0.527 2
 UniProt:Q96P48 ARAP1  2 0.508 2
 UniProt:P01106 MYC  2 0.462 3
 UniProt:P22415 USF1  2 0.462 2
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