Reactome | NDUFA12 [mitochondrial inner membrane]

NDUFA12 [mitochondrial inner membrane]

Stable Identifier

R-HSA-59864

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial inner membrane

Synonyms

NADH-ubiquinone oxidoreductase subunit B17.2 , Complex I-B17.2, CI-B17.2, CIB17.2, 13 kDa differentiation-associated protein

Locations in the PathwayBrowser for interactor UniProt:O95169 NDUFB8

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External Reference Information

External Reference

UniProt:Q9UI09 NDUFA12

Gene Names

NDUFA12, DAP13

Chain

chain:1-145

Reference Genes

BioGPS Gene:55967 NDUFA12

COSMIC (genes):NDUFA12 NDUFA12

CTD Gene:55967 NDUFA12

dbSNP Gene:55967 NDUFA12

ENSEMBL:ENSG00000184752 NDUFA12

ENSEMBL_homo_sapiens_GENE:ENSG00000184752.14 NDUFA12

HGNC:23987 NDUFA12

KEGG Gene (Homo sapiens):55967 NDUFA12

Monarch:55967 NDUFA12

NCBI Gene:55967 NDUFA12

OMIM:614530 NDUFA12

UCSC:Q9UI09 NDUFA12

Reference Transcript

Other Identifiers

11757589_a_at

223244_PM_s_at

223244_s_at

3466302

3466303

3466304

3466308

3466312

3466313

3466314

52104_at

55967

7965515

A_23_P76557

A_33_P3241753

GO:0003824

GO:0005215

GO:0005515

GO:0005739

GO:0005743

GO:0005747

GO:0005829

GO:0006091

GO:0006979

GO:0007005

GO:0007585

GO:0008137

GO:0009060

GO:0016020

GO:0016491

GO:0032981

GO:0042775

GO:0042776

GO:0043226

GO:0055086

GO:0065003

GO:0070469

GO:1901135

HMNXSV003006229

ILMN_1737738

PH_hs_0028878

TC12001827.hg

U34343_at

g9651636_3p_s_at

Participates

as a component of

as an input of

NDUF subunits bind to form the FP subcomplex (Homo sapiens)

Inferred To

NDUFA12 [mitochondrial inner membrane] (Bos taurus)

NDUFA12 [mitochondrial inner membrane] (Caenorhabditis elegans)

NDUFA12 [mitochondrial inner membrane] (Canis familiaris)

NDUFA12 [mitochondrial inner membrane] (Gallus gallus)

NDUFA12 [mitochondrial inner membrane] (Sus scrofa)

Homologues of NDUFA12 [mitochondrial inner membrane] (Bos taurus)

ndufa12 [mitochondrial inner membrane] (Danio rerio)

ndufa12 [mitochondrial inner membrane] (Dictyostelium discoideum)

ndufa12 [mitochondrial inner membrane] (Xenopus tropicalis)

LOC101906178 [mitochondrial inner membrane] (Bos taurus)

ND-B17.2 [mitochondrial inner membrane] (Drosophila melanogaster)

Ndufa12 [mitochondrial inner membrane] (Mus musculus)

Ndufa12 [mitochondrial inner membrane] (Rattus norvegicus)

Cross References

RefSeq

NP_001245267.1, NP_061326.1

OpenTargets

ENSG00000184752

HPA

ENSG00000184752-NDUFA12

GeneCards

Q9UI09

Ensembl

ENSG00000184752, ENSP00000450130, ENST00000327772, ENST00000547986, ENSP00000330737

PRO

Q9UI09

Pharos - Targets

Q9UI09

Orphanet

23357

HMDB Protein

HMDBP00124

PDB

5XTH, 5XTI, 5XTB, 5XTD

Interactors (29)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O75489 NDUFS3	2	NDUFS3 [mitochondrial matrix] (R-HSA-163927) NDUFS3 [cytosol] (R-HSA-9714751)	0.725	7
UniProt:O75380 NDUFS6	1	NDUFS6 [mitochondrial inner membrane] (R-HSA-163922)	0.643	5
UniProt:Q9P0J0 NDUFA13	8	NDUFA13 [mitochondrial inner membrane] (R-HSA-59936) NDUFA13(41-49) [mitochondrial inner membrane] (R-HSA-9839958) NDUFA13(100-108) [mitochondrial inner membrane] (R-HSA-9839959) NDUFA13(109-144) [mitochondrial inner membrane] (R-HSA-9839968) NDUFA13(2-19) [mitochondrial inner membrane] (R-HSA-9839966) NDUFA13(69-99) [mitochondrial inner membrane] (R-HSA-9839964) NDUFA13(20-40) [mitochondrial inner membrane] (R-HSA-9839963) NDUFA13(50-68) [mitochondrial inner membrane] (R-HSA-9839961)	0.643	5
UniProt:O75251 NDUFS7	1	NDUFS7 [mitochondrial matrix] (R-HSA-6788521)	0.643	5
UniProt:O43678 NDUFA2	1	NDUFA2 [mitochondrial inner membrane] (R-HSA-60178)	0.564	3
UniProt:Q9H2B2 SYT4			0.556	3
UniProt:Q6PL24 TMED8			0.556	3
UniProt:Q96JP2 MY15B			0.556	3
UniProt:O95182 NDUFA7	1	NDUFA7 [mitochondrial inner membrane] (R-HSA-59858)	0.527	3
UniProt:Q8WTR4 GDPD5	1	GDPD5 [endoplasmic reticulum membrane] (R-HSA-6814136)	0.527	2
UniProt:Q9Y6M9 NDUFB9	1	NDUFB9 [mitochondrial inner membrane] (R-HSA-60176)	0.527	2
UniProt:O95169 NDUFB8	4	NDUFB8 [mitochondrial inner membrane] (R-HSA-163938) NDUFB8(1-28) [mitochondrial matrix] (R-HSA-8986166) NDUFB8(1-186) [mitochondrial inner membrane] (R-HSA-8986184) NDUFB8(1-186) [mitochondrial intermembrane space] (R-HSA-8986140)	0.527	2
UniProt:O43676 NDUFB3	1	NDUFB3 [mitochondrial inner membrane] (R-HSA-59930)	0.527	3
UniProt:O43674 NDUFB5	1	NDUFB5 [mitochondrial inner membrane] (R-HSA-163944)	0.527	2
UniProt:Q9GZM5 YIPF3			0.527	3
UniProt:P56556 NDUFA6	1	NDUFA6 [mitochondrial inner membrane] (R-HSA-59932)	0.527	2
UniProt:Q9NX14 NDUFB11	1	NDUFB11 [mitochondrial inner membrane] (R-HSA-163933)	0.527	3
UniProt:O95292 VAPB	2	VAPB [endoplasmic reticulum membrane] (R-HSA-429718) VAPB [Golgi membrane] (R-HSA-9715115)	0.527	3
UniProt:O00483 NDUFA4	1	NDUFA4 [mitochondrial inner membrane] (R-HSA-60617)	0.527	5
UniProt:P17568 NDUFB7	1	NDUFB7 [mitochondrial inner membrane] (R-HSA-59940)	0.527	2
UniProt:P19404 NDUFV2	1	NDUFV2 [mitochondrial inner membrane] (R-HSA-163939)	0.527	3
UniProt:Q8NCL4 GALNT6	1	GALNT6 [Golgi membrane] (R-HSA-913608)	0.527	2
UniProt:P51970 NDUFA8	1	NDUFA8 [mitochondrial inner membrane] (R-HSA-60627)	0.527	2
UniProt:P56181 NDUFV3	1	NDUFV3 [mitochondrial inner membrane] (R-HSA-163943)	0.527	4
UniProt:P03915 MT-ND5	1	MT-ND5 [mitochondrial inner membrane] (R-HSA-60565)	0.527	2
UniProt:O43181 NDUFS4	1	NDUFS4 [mitochondrial inner membrane] (R-HSA-163946)	0.527	3
UniProt:P27930 IL1R2	1	IL1R2 [plasma membrane] (R-HSA-197598)	0.527	3
UniProt:Q16795 NDUFA9	1	NDUFA9 [mitochondrial matrix] (R-HSA-163942)	0.527	4
UniProt:O43920 NDUFS5	1	NDUFS5 [mitochondrial inner membrane] (R-HSA-60226)	0.527	3

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