Reactome | NDUFB3 [mitochondrial inner membrane]

NDUFB3 [mitochondrial inner membrane]

Stable Identifier

R-HSA-59930

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial inner membrane

Synonyms

NADH-ubiquinone oxidoreductase B12 subunit , Complex I-B12, CI-B12

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:O43676 NDUFB3

Gene Names

NDUFB3

Chain

initiator methionine:, chain:2-98

Reference Genes

BioGPS Gene:4709 NDUFB3

COSMIC (genes):NDUFB3 NDUFB3

CTD Gene:4709 NDUFB3

dbSNP Gene:4709 NDUFB3

ENSEMBL:ENSG00000119013 NDUFB3

ENSEMBL_homo_sapiens_GENE:ENSG00000119013.10 NDUFB3

HGNC:7698 NDUFB3

KEGG Gene (Homo sapiens):4709 NDUFB3

Monarch:4709 NDUFB3

NCBI Gene:4709 NDUFB3

OMIM:603839 NDUFB3

UCSC:O43676 NDUFB3

Reference Transcript

Other Identifiers

11717159_a_at

11763960_a_at

11764061_s_at

16889399

203371_PM_s_at

203371_s_at

2522600

2522601

2522602

2522603

2522604

2522605

2522606

2522607

2522608

2522609

2522612

2522613

3535996

3551934

38981_at

4709

8047372

A_23_P51009

A_33_P3413597

GE54401

GO:0003824

GO:0005215

GO:0005739

GO:0005743

GO:0005747

GO:0006091

GO:0006120

GO:0007005

GO:0008137

GO:0009060

GO:0016020

GO:0016491

GO:0022900

GO:0032981

GO:0042776

GO:0043226

GO:0055086

GO:0065003

GO:0070469

GO:1901135

HMNXSV003004196

ILMN_2119937

ILMN_2119945

PH_hs_0035525

TC02001171.hg

g4505360_3p_a_at

Participates

as a component of

HP subcomplex [mitochondrial inner membrane] (Homo sapiens)

Inferred To

Ndufb3 [mitochondrial inner membrane] (Mus musculus)

Ndufb3 [mitochondrial inner membrane] (Rattus norvegicus)

NDUFB3 [mitochondrial inner membrane] (Bos taurus)

NDUFB3 [mitochondrial inner membrane] (Canis familiaris)

NDUFB3 [mitochondrial inner membrane] (Gallus gallus)

NDUFB3 [mitochondrial inner membrane] (Sus scrofa)

ndub-3 [mitochondrial inner membrane] (Caenorhabditis elegans)

ndufb3 [mitochondrial inner membrane] (Danio rerio)

ndufb3 [mitochondrial inner membrane] (Xenopus tropicalis)

ND-B12 [mitochondrial inner membrane] (Drosophila melanogaster)

Cross References

RefSeq

XP_016859675.1, NP_002482.1, XP_011509532.1, NP_001244031.1

OpenTargets

ENSG00000119013

HPA

ENSG00000119013-NDUFB3

GeneCards

O43676

Ensembl

ENSP00000508132, ENSP00000508208, ENSP00000401834, ENSP00000410600, ENSP00000507925, ENSP00000237889, ENST00000682325, ENSP00000407336, ENST00000684420, ENST00000684175, ENST00000433898, ENST00000454214, ENSG00000119013, ENST00000237889, ENST00000450023

PRO

O43676

Pharos - Targets

O43676

Orphanet

20812

HMDB Protein

HMDBP00172

PDB

5XTI, 5XTH, 5XTD, 5XTC

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O75489 NDUFS3	2	NDUFS3 [mitochondrial matrix] (R-HSA-163927) NDUFS3 [cytosol] (R-HSA-9714751)	0.643	6
UniProt:Q6UWR7 ENPP6	1	ENPP6 [plasma membrane] (R-HSA-6814799)	0.527	2
UniProt:Q9P0J0 NDUFA13	8	NDUFA13 [mitochondrial inner membrane] (R-HSA-59936) NDUFA13(41-49) [mitochondrial inner membrane] (R-HSA-9839958) NDUFA13(100-108) [mitochondrial inner membrane] (R-HSA-9839959) NDUFA13(109-144) [mitochondrial inner membrane] (R-HSA-9839968) NDUFA13(2-19) [mitochondrial inner membrane] (R-HSA-9839966) NDUFA13(69-99) [mitochondrial inner membrane] (R-HSA-9839964) NDUFA13(20-40) [mitochondrial inner membrane] (R-HSA-9839963) NDUFA13(50-68) [mitochondrial inner membrane] (R-HSA-9839961)	0.527	2
UniProt:Q9UI09 NDUFA12	1	NDUFA12 [mitochondrial inner membrane] (R-HSA-59864)	0.527	3
UniProt:O75380 NDUFS6	1	NDUFS6 [mitochondrial inner membrane] (R-HSA-163922)	0.527	4