Reactome | NDUFA2 [mitochondrial inner membrane]

NDUFA2 [mitochondrial inner membrane]

Stable Identifier

R-HSA-60178

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial inner membrane

Synonyms

NADH-ubiquinone oxidoreductase B8 subunit , Complex I-B8, CI-B8

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O43678 NDUFA2

Gene Names

NDUFA2

Chain

initiator methionine:, chain:2-99

Reference Genes

BioGPS Gene:4695 NDUFA2

COSMIC (genes):NDUFA2 NDUFA2

CTD Gene:4695 NDUFA2

dbSNP Gene:4695 NDUFA2

ENSEMBL:ENSG00000131495 NDUFA2

HGNC:7685 NDUFA2

KEGG:hsa:4695 NDUFA2

Monarch:4695 NDUFA2

NCBI Gene:4695 NDUFA2

OMIM:602137 NDUFA2

UCSC:O43678 NDUFA2

Reference Transcript

Other Identifiers

11718831_at

17000800

209223_PM_at

209223_at

209224_PM_s_at

209224_s_at

2878447

2878449

2878450

2878451

2878455

2878456

2878457

2878458

40546_s_at

4695

63514_at

7894479

7895842

8114618

A_23_P257795

A_24_P12218

GE54402

GO:0001835

GO:0003824

GO:0005215

GO:0005739

GO:0005743

GO:0006091

GO:0006120

GO:0008137

GO:0009060

GO:0016491

GO:0031966

GO:0032981

GO:0042776

GO:0043226

GO:0045271

GO:0055085

GO:0055086

GO:0065003

GO:1901135

GO:1902600

HMNXSV003053434

Hs.163867.0.S1_3p_at

PH_hs_0009907

PH_hs_0035627

TC05001862.hg

TC05003269.hg

g13277539_3p_a_at

Participates

as a member of

Substrate of LONP1 (mitochondrial inner membrane) [mitochondrial inner membrane] (Homo sapiens)

as a component of

HP subcomplex [mitochondrial inner membrane] (Homo sapiens)

Inferred To

ndua-2 [mitochondrial inner membrane] (Caenorhabditis elegans)

ndufa2 [mitochondrial inner membrane] (Danio rerio)

ndufa2 [mitochondrial inner membrane] (Xenopus tropicalis)

LOC106507363 [mitochondrial inner membrane] (Sus scrofa)

ND-B8 [mitochondrial inner membrane] (Drosophila melanogaster)

Ndufa2 [mitochondrial inner membrane] (Mus musculus)

Ndufa2 [mitochondrial inner membrane] (Rattus norvegicus)

NDUFA2 [mitochondrial inner membrane] (Bos taurus)

NDUFA2 [mitochondrial inner membrane] (Canis familiaris)

NDUFA2 [mitochondrial inner membrane] (Dictyostelium discoideum)

NDUFA2 [mitochondrial inner membrane] (Gallus gallus)

Cross References

ENSEMBL

ENSP00000252102, ENSG00000131495, ENST00000252102, ENSP00000427220, ENST00000512088

OpenTargets

ENSG00000131495

GeneCards

NDUFA2

HPA

ENSG00000131495-NDUFA2

PRO

O43678

Pharos - Targets

O43678

Orphanet

NDUFA2

HMDB Protein

HMDBP00159

PDB

1S3A, 5XTI, 5XTH, 5XTB, 5XTD

Interactors (9)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O75489 NDUFS3	2	NDUFS3 [mitochondrial matrix] (R-HSA-163927) NDUFS3 [cytosol] (R-HSA-9714751)	0.802	9
UniProt:O75380 NDUFS6	1	NDUFS6 [mitochondrial inner membrane] (R-HSA-163922)	0.669	6
UniProt:O43181 NDUFS4	1	NDUFS4 [mitochondrial inner membrane] (R-HSA-163946)	0.564	3
UniProt:P56181 NDUFV3	1	NDUFV3 [mitochondrial inner membrane] (R-HSA-163943)	0.564	5
UniProt:O43920 NDUFS5	1	NDUFS5 [mitochondrial inner membrane] (R-HSA-60226)	0.564	3
UniProt:Q9P0J0 NDUFA13	8	NDUFA13 [mitochondrial inner membrane] (R-HSA-59936) NDUFA13(41-49) [mitochondrial inner membrane] (R-HSA-9839958) NDUFA13(100-108) [mitochondrial inner membrane] (R-HSA-9839959) NDUFA13(109-144) [mitochondrial inner membrane] (R-HSA-9839968) NDUFA13(2-19) [mitochondrial inner membrane] (R-HSA-9839966) NDUFA13(69-99) [mitochondrial inner membrane] (R-HSA-9839964) NDUFA13(20-40) [mitochondrial inner membrane] (R-HSA-9839963) NDUFA13(50-68) [mitochondrial inner membrane] (R-HSA-9839961)	0.564	3
UniProt:Q9UI09 NDUFA12	1	NDUFA12 [mitochondrial inner membrane] (R-HSA-59864)	0.564	3
UniProt:P49821 NDUFV1	1	NDUFV1 [mitochondrial inner membrane] (R-HSA-163926)	0.564	3
UniProt:P19404 NDUFV2	1	NDUFV2 [mitochondrial inner membrane] (R-HSA-163939)	0.564	3