Reactome | NDUFB10 [mitochondrial inner membrane]

NDUFB10 [mitochondrial inner membrane]

Stable Identifier

R-HSA-60194

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial inner membrane

Synonyms

NADH-ubiquinone oxidoreductase PDSW subunit , Complex I-PDSW, CI-PDSW

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O96000 NDUFB10

Gene Names

NDUFB10

Chain

chain:1-172

Reference Genes

BioGPS Gene:4716 O960002

COSMIC (genes):NDUFB10 NDUFB10

CTD Gene:4716 O960002

dbSNP Gene:4716 NDUFB10

ENSEMBL:ENSG00000140990 NDUFB10

HGNC:7696 O960002

KEGG:hsa:4716 O960002

Monarch:4716 O960002

NCBI Gene:4716 O960002

OMIM:603843 O960002

UCSC:O96000 O960002

Reference Transcript

RefSeq:NM_004548.3 O960002

Participates

as a component of

HP subcomplex [mitochondrial inner membrane] (Homo sapiens)

Inferred To

Ndufb10 [mitochondrial inner membrane] (Mus musculus)

Ndufb10 [mitochondrial inner membrane] (Rattus norvegicus)

NDUFB10 [mitochondrial inner membrane] (Bos taurus)

NDUFB10 [mitochondrial inner membrane] (Canis familiaris)

NDUFB10 [mitochondrial inner membrane] (Gallus gallus)

NDUFB10 [mitochondrial inner membrane] (Sus scrofa)

ndub-10 [mitochondrial inner membrane] (Caenorhabditis elegans)

ND-PDSW [mitochondrial inner membrane] (Drosophila melanogaster)

ndufb10 [mitochondrial inner membrane] (Danio rerio)

ndufb10 [mitochondrial inner membrane] (Xenopus tropicalis)

Cross References

RefSeq

NP_004539.1

ENSEMBL

ENSG00000291930, ENST00000543683, ENSG00000140990, ENSP00000268668, ENSP00000445086, ENST00000268668, ENSP00000517571, ENST00000709233, ENST00000709234, ENSP00000517572

OpenTargets

ENSG00000140990

GeneCards

NDUFB10

HPA

ENSG00000140990-NDUFB10

PRO

O96000

Pharos - Targets

O96000

GlyGen

O96000

Orphanet

NDUFB10

HMDB Protein

HMDBP00116

PDB

5XTD, 5XTC, 5XTI, 5XTH

Interactors (10)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.666	13
UniProt:O15160 POLR1C	2	POLR1C [cytosol] (R-HSA-1964454) POLR1C [nucleoplasm] (R-HSA-63498)	0.556	3
UniProt:P05455 SSB	1	SSB [nucleoplasm] (R-HSA-58418)	0.556	3
UniProt:O14964 HGS	2	HGS [cytosol] (R-HSA-182954) HGS [phagocytic vesicle lumen] (R-HSA-9635660)	0.556	3
UniProt:P19404 NDUFV2	1	NDUFV2 [mitochondrial inner membrane] (R-HSA-163939)	0.527	2
UniProt:O75380 NDUFS6	1	NDUFS6 [mitochondrial inner membrane] (R-HSA-163922)	0.527	4
UniProt:O43920 NDUFS5	1	NDUFS5 [mitochondrial inner membrane] (R-HSA-60226)	0.527	2
UniProt:P10636-8 MAPT	3	MAPT-8 [cytosol] (R-HSA-9619519) p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol] (R-HSA-9836400) p-S262,S356,S396-MAPT-8 [cytosol] (R-HSA-9619521)	0.527	4
UniProt:Q9P0J0 NDUFA13	8	NDUFA13 [mitochondrial inner membrane] (R-HSA-59936) NDUFA13(41-49) [mitochondrial inner membrane] (R-HSA-9839958) NDUFA13(100-108) [mitochondrial inner membrane] (R-HSA-9839959) NDUFA13(109-144) [mitochondrial inner membrane] (R-HSA-9839968) NDUFA13(2-19) [mitochondrial inner membrane] (R-HSA-9839966) NDUFA13(69-99) [mitochondrial inner membrane] (R-HSA-9839964) NDUFA13(20-40) [mitochondrial inner membrane] (R-HSA-9839963) NDUFA13(50-68) [mitochondrial inner membrane] (R-HSA-9839961)	0.527	2
UniProt:O75489 NDUFS3	2	NDUFS3 [mitochondrial matrix] (R-HSA-163927) NDUFS3 [cytosol] (R-HSA-9714751)	0.527	4