Reactome | NDUFA5 [mitochondrial inner membrane]

NDUFA5 [mitochondrial inner membrane]

Stable Identifier

R-HSA-60599

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial inner membrane

Synonyms

NADH-ubiquinone oxidoreductase 13 kDa-B subunit , Complex I-13Kd-B, CI-13Kd-B, Complex I subunit B13

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q16718 NDUFA5

Gene Names

NDUFA5

Chain

initiator methionine:, chain:2-116

Reference Genes

BioGPS Gene:4698 NDUFA5

COSMIC (genes):NDUFA5 NDUFA5

CTD Gene:4698 NDUFA5

dbSNP Gene:4698 NDUFA5

ENSEMBL:ENSG00000128609 NDUFA5

ENSEMBL_homo_sapiens_GENE:ENSG00000128609.16 NDUFA5

HGNC:7688 NDUFA5

KEGG Gene (Homo sapiens):4698 NDUFA5

Monarch:4698 NDUFA5

NCBI Gene:4698 NDUFA5

OMIM:601677 NDUFA5

UCSC:Q16718 NDUFA5

Reference Transcript

Other Identifiers

11754079_s_at

201304_PM_at

201304_at

2523421

2523422

2523423

2523424

3070644

3070645

3070646

3070647

3070648

3070649

3070650

3070655

3070657

3070659

3070660

3070661

3070662

3070663

3070664

3070666

3070669

3070672

3070674

3070675

3070676

3096901

3690326

38462_at

4698

74839_r_at

8142663

A_23_P215751

A_32_P96641

GE58352

GO:0003824

GO:0005215

GO:0005515

GO:0005739

GO:0005743

GO:0005747

GO:0006091

GO:0006120

GO:0007005

GO:0008137

GO:0009060

GO:0016020

GO:0016491

GO:0022904

GO:0032981

GO:0042776

GO:0043226

GO:0045271

GO:0055086

GO:0065003

GO:0070469

GO:1901135

HMNXSV003035421

ILMN_1759973

ILMN_1764095

ILMN_1824709

PH_hs_0027720

PH_hs_0031370

TC07001821.hg

U53468_at

g13699821_3p_at

Participates

as a component of

HP subcomplex [mitochondrial inner membrane] (Homo sapiens)

Other forms of this molecule

NDUFA5 [endoplasmic reticulum membrane]

Inferred To

NDUFA5 [mitochondrial inner membrane] (Bos taurus)

NDUFA5 [mitochondrial inner membrane] (Caenorhabditis elegans)

NDUFA5 [mitochondrial inner membrane] (Canis familiaris)

NDUFA5 [mitochondrial inner membrane] (Gallus gallus)

NDUFA5 [mitochondrial inner membrane] (Sus scrofa)

Ndufa5 [mitochondrial inner membrane] (Mus musculus)

Ndufa5 [mitochondrial inner membrane] (Rattus norvegicus)

ND-13B [mitochondrial inner membrane] (Drosophila melanogaster)

ndufa5 [mitochondrial inner membrane] (Danio rerio)

ndufa5 [mitochondrial inner membrane] (Xenopus tropicalis)

Cross References

RefSeq

NP_001269351.1, NP_001269349.1, NP_004991.1, NP_001269350.1, NP_001269348.1

OpenTargets

ENSG00000128609

GeneCards

Q16718

HPA

ENSG00000128609-NDUFA5

Ensembl

ENSP00000417142, ENST00000471770, ENSG00000128609, ENSP00000347988, ENST00000355749

PRO

Q16718

Pharos - Targets

Q16718

Orphanet

24738

HMDB Protein

HMDBP00175

PDB

5XTH, 5XTB, 5XTI, 5XTD

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O75489 NDUFS3	2	NDUFS3 [mitochondrial matrix] (R-HSA-163927) NDUFS3 [cytosol] (R-HSA-9714751)	0.845	13
UniProt:Q92993 KAT5	1	KAT5 [nucleoplasm] (R-HSA-3321979)	0.556	3
UniProt:Q9P0J0 NDUFA13	8	NDUFA13 [mitochondrial inner membrane] (R-HSA-59936) NDUFA13(41-49) [mitochondrial inner membrane] (R-HSA-9839958) NDUFA13(100-108) [mitochondrial inner membrane] (R-HSA-9839959) NDUFA13(109-144) [mitochondrial inner membrane] (R-HSA-9839968) NDUFA13(2-19) [mitochondrial inner membrane] (R-HSA-9839966) NDUFA13(69-99) [mitochondrial inner membrane] (R-HSA-9839964) NDUFA13(20-40) [mitochondrial inner membrane] (R-HSA-9839963) NDUFA13(50-68) [mitochondrial inner membrane] (R-HSA-9839961)	0.527	2
UniProt:Q9P032 NDUFAF4	1	NDUFAF4 [mitochondrial inner membrane] (R-HSA-5689124)	0.527	4
UniProt:Q08379 GOLGA2	3	p-S37-GOLGA2 [Golgi membrane] (R-HSA-2172179) GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-2167933) GOLGA2 [Golgi membrane] (R-HSA-6808764)	0.488	2