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RSF complex binds the centromere
Stable Identifier
R-HSA-606287
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
Locations in the PathwayBrowser
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Cell Cycle (Homo sapiens)
Chromosome Maintenance (Homo sapiens)
Nucleosome assembly (Homo sapiens)
Deposition of new CENPA-containing nucleosomes at the centromere (Homo sapiens)
RSF complex binds the centromere (Homo sapiens)
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
The RSF complex binds the centromere in mid-G1 phase after deposition of new CENPA-containing nucleosomes has occurred. The RSF complex is required for stable incorporation of the previously deposited CENPA-containing nucleosomes.
Literature References
PubMed ID
Title
Journal
Year
19398759
Active establishment of centromeric CENP-A chromatin by RSF complex
Perpelescu, M
,
Yoda, K
,
Yang, H
,
Obuse, C
,
Nozaki, N
J Cell Biol
2009
Participants
Input
CCAN:DNA:CASC5:Mis18 complex:HJURP complex:CENPA nucleosome [nucleoplasm]
(Homo sapiens)
RSF Complex [nucleoplasm]
(Homo sapiens)
Output
CCAN:DNA:CASC5:Centromeric nucleosome:RSF complex [nucleoplasm]
(Homo sapiens)
HJURP:NPM1:RBBP4:RBBP7:RUVBL1 [nucleoplasm]
(Homo sapiens)
Mis18 Complex [nucleoplasm]
(Homo sapiens)
Participates
as an event of
Deposition of new CENPA-containing nucleosomes at the centromere (Homo sapiens)
Orthologous Events
RSF complex binds the centromere (Bos taurus)
RSF complex binds the centromere (Gallus gallus)
RSF complex binds the centromere (Mus musculus)
RSF complex binds the centromere (Rattus norvegicus)
RSF complex binds the centromere (Sus scrofa)
Authored
May, B (2010-04-15)
Reviewed
Dunleavy, EM (2010-05-30)
Almouzni-Pettinotti, G (2010-05-30)
Foltz, DR (2010-06-15)
Created
May, B (2010-04-17)
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