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NPM1 [nucleoplasm]
Stable Identifier
R-HSA-606320
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Nucleophosmin, B23, NPM_HUMAN
Locations in the PathwayBrowser for interactor UniProt:Q01780 EXOSC10
Expand all
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
Signaling by ALK in cancer (Homo sapiens)
Signaling by ALK fusions and activated point mutants (Homo sapiens)
Nuclear events stimulated by ALK signaling in cancer (Homo sapiens)
NPM1-ALK binds NPM1 and FOXM1 (Homo sapiens)
NPM1 [nucleoplasm] (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
HIV Infection (Homo sapiens)
Host Interactions of HIV factors (Homo sapiens)
Interactions of Rev with host cellular proteins (Homo sapiens)
Nuclear import of Rev protein (Homo sapiens)
Disassembly of the Rev-importin beta-B23:Ran-GTP complex (Homo sapiens)
NPM1 [nucleoplasm] (Homo sapiens)
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors (Homo sapiens)
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation (Homo sapiens)
NPM1 binds TFAP2A homodimer (Homo sapiens)
NPM1 [nucleoplasm] (Homo sapiens)
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
SUMOylation (Homo sapiens)
SUMO E3 ligases SUMOylate target proteins (Homo sapiens)
SUMOylation of transcription cofactors (Homo sapiens)
SUMOylation of NPM1 with SUMO1 (Homo sapiens)
NPM1 [nucleoplasm] (Homo sapiens)
SUMOylation of NPM1 with SUMO2,3 (Homo sapiens)
NPM1 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:P06748 NPM1
Gene Names
NPM1, NPM
Chain
chain:1-294
Reference Genes
BioGPS Gene:4869 NPM1
COSMIC (genes):NPM1 NPM1
CTD Gene:4869 NPM1
dbSNP Gene:4869 NPM1
ENSEMBL:ENSG00000181163 NPM1
ENSEMBL_homo_sapiens_GENE:ENSG00000181163.14 NPM1
HGNC:7910 NPM1
KEGG Gene (Homo sapiens):4869 NPM1
Monarch:4869 NPM1
NCBI Gene:4869 NPM1
OMIM:164040 NPM1
UCSC:P06748 NPM1
Reference Transcript
RefSeq:NM_199185.3 NPM1
RefSeq:NM_002520.6 NPM1
RefSeq:NM_001037738.2 NPM1
Other Identifiers
11730790_x_at
11730912_at
11754066_x_at
11757362_x_at
11757386_x_at
16656591
16656593
16656595
18670158
18670159
18670165
18670166
18670167
200063_PM_s_at
200063_s_at
221691_3p_x_at
221691_PM_x_at
221691_x_at
221923_PM_s_at
221923_s_at
2326906
2666248
2840617
2840618
2840620
2840621
2840623
2840626
2840627
2840628
2840629
2840631
2840633
2840638
2840640
2840641
2840642
2840643
2840646
2840647
2840648
2867271
2867272
2867273
2867274
2867275
2867281
2867283
2960052
2960054
3100478
3100479
3136166
3404467
3404471
38542_at
4869
78344_at
7892530
7892853
7893382
7893420
7893571
7893657
7894485
7894919
7895119
7895225
7895472
7895509
7896054
8109975
8180407
8180408
8180409
88066_s_at
A_14_P116462
A_14_P127485
A_23_P214037
A_24_P188941
GE79895
GO:0000055
GO:0000056
GO:0001046
GO:0001558
GO:0001652
GO:0003676
GO:0003677
GO:0003682
GO:0003713
GO:0003723
GO:0004860
GO:0005515
GO:0005634
GO:0005654
GO:0005730
GO:0005737
GO:0005813
GO:0005815
GO:0005829
GO:0005840
GO:0005856
GO:0005925
GO:0006281
GO:0006325
GO:0006334
GO:0006338
GO:0006351
GO:0006355
GO:0006407
GO:0006884
GO:0006886
GO:0006913
GO:0007010
GO:0007098
GO:0007165
GO:0008104
GO:0008284
GO:0008285
GO:0010608
GO:0010629
GO:0010824
GO:0010825
GO:0010826
GO:0012501
GO:0015934
GO:0015935
GO:0016020
GO:0016071
GO:0016607
GO:0019843
GO:0019901
GO:0023052
GO:0030957
GO:0031328
GO:0031398
GO:0031616
GO:0031647
GO:0032071
GO:0032991
GO:0032993
GO:0034644
GO:0036211
GO:0042254
GO:0042255
GO:0042273
GO:0042274
GO:0042393
GO:0042802
GO:0042803
GO:0043023
GO:0043024
GO:0043066
GO:0043226
GO:0043516
GO:0044387
GO:0045727
GO:0045893
GO:0045944
GO:0046599
GO:0048025
GO:0050821
GO:0051059
GO:0051082
GO:0051092
GO:0051726
GO:0060090
GO:0060699
GO:0060735
GO:0065003
GO:0090398
GO:0098772
GO:0140110
GO:0140297
GO:0140693
GO:1902629
GO:1902751
GO:1904751
GO:1990904
HMNXSV003029586
HMNXSV003034873
HMNXSV003056309
Hs.9614.1.A1_3p_a_at
ILMN_1678775
M23613_at
PH_hs_0030093
TC01000357.hg
TC05000942.hg
g12803184_3p_a_at
g13536990_3p_s_at
Participates
as an input of
SUMOylation of NPM1 with SUMO1 (Homo sapiens)
SUMOylation of NPM1 with SUMO2,3 (Homo sapiens)
NPM1-ALK binds NPM1 and FOXM1 (Homo sapiens)
NPM1 binds TFAP2A homodimer (Homo sapiens)
as a component of
NPM1-ALK;NPM1:FOXM1 [nucleoplasm] (Homo sapiens)
HJURP:NPM1:RBBP4:RBBP7:RUVBL1:CENPA:H4 [nucleoplasm] (Homo sapiens)
HJURP:NPM1:RBBP4:RBBP7:RUVBL1 [nucleoplasm] (Homo sapiens)
NPM1:TFAP2A homodimer [nucleoplasm] (Homo sapiens)
Rev:Importin-beta:B23 [nucleoplasm] (Homo sapiens)
as an output of
Disassembly of the Rev-importin beta-B23:Ran-GTP complex (Homo sapiens)
Other forms of this molecule
monoSUMO1-K263-NPM1 [nucleoplasm]
polySUMO2,3-K263-NPM1 [nucleoplasm]
NPM1(1-117)-p-7Y-ALK(1058-1620) fusion [nucleoplasm]
NPM1(1-117)-p-7Y-ALK(1068-1620) fusion [cytosol]
NPM1(1-117)-ALK(1068-1620) fusion [cytosol]
NPM1(1-117)-p-7Y-ALK(1058-1620) fusion [cytosol]
NPM1(1-117)-ALK(1058-1620) fusion [cytosol]
NPM1 [granular component]
NPM1 [cytosol]
p-S4-NPM1 [cytosol]
Inferred To
LOC511386 [nucleoplasm]
(Bos taurus)
Nph [nucleoplasm]
(Drosophila melanogaster)
NPM1 [nucleoplasm]
(Bos taurus)
NPM1 [nucleoplasm]
(Canis familiaris)
NPM1 [nucleoplasm]
(Gallus gallus)
NPM1 [nucleoplasm]
(Sus scrofa)
CG12644 [nucleoplasm]
(Drosophila melanogaster)
npm1 [nucleoplasm]
(Xenopus tropicalis)
Nlp [nucleoplasm]
(Drosophila melanogaster)
Homologues of NPM1 [nucleoplasm]
(Bos taurus)
Homologues of NPM1 [nucleoplasm]
(Drosophila melanogaster)
Npm1 [nucleoplasm]
(Mus musculus)
Npm1 [nucleoplasm]
(Rattus norvegicus)
Cross References
RefSeq
NP_001032827.1
,
NP_954654.1
,
NP_002511.1
OpenTargets
ENSG00000181163
HPA
ENSG00000181163-NPM1
GeneCards
P06748
Ensembl
ENSP00000428755
,
ENST00000393820
,
ENST00000517671
,
ENSP00000296930
,
ENST00000296930
,
ENSP00000503235
,
ENST00000351986
,
ENSP00000377408
,
ENSG00000181163
,
ENSP00000341168
,
ENST00000678280
PRO
P06748
Pharos - Targets
P06748
Orphanet
17401
PDB
8AH2
,
2LLH
,
7OBH
,
2VXD
,
8AS5
,
7OBG
,
2P1B
,
5EHD
Interactors (209)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q96BK5 PINX1
0.81
13
UniProt:Q9H4L4 SENP3
1
SENP3 [nucleoplasm]
(R-HSA-2984296)
0.78
7
UniProt:Q86SE8 NPM2
1
NPM2 [nucleoplasm]
(R-HSA-9821980)
0.743
8
UniProt:O75607 NPM3
0.725
6
UniProt:Q96GD4 AURKB
3
polySUMO2,3-K202-AURKB [cytosol]
(R-HSA-4655414)
AURKB [nucleoplasm]
(R-HSA-4655360)
AURKB [cytosol]
(R-HSA-174231)
0.712
6
UniProt:Q9BQG0 MYBBP1A
1
MYBBP1A [nucleoplasm]
(R-HSA-5250650)
0.712
4
UniProt:Q13823 NOG2
0.706
4
UniProt:Q14684 RRP1B
0.706
5
UniProt:P46777 RPL5
1
RPL5 [cytosol]
(R-HSA-72482)
0.706
4
UniProt:Q14137 BOP1
1
BOP1 [nucleoplasm]
(R-HSA-6791206)
0.706
4
UniProt:Q00987 MDM2
11
PolyUb-MDM2 [nucleoplasm]
(R-HSA-6782472)
monoSUMO1-K182-MDM2 [nucleoplasm]
(R-HSA-3000408)
MDM2 [plasma membrane]
(R-HSA-416843)
MDM2 [endocytic vesicle membrane]
(R-HSA-416849)
p-5S,T-MDM2 [nucleoplasm]
(R-HSA-6804954)
PolyUb,p-S166,S188-MDM2 [nucleoplasm]
(R-HSA-6795669)
p-S166,S188,T218-MDM2 [nucleoplasm]
(R-HSA-6792862)
MDM2 [nucleoplasm]
(R-HSA-69486)
MDM2 [cytosol]
(R-HSA-198644)
p-S166,S188-MDM2 [cytosol]
(R-HSA-198638)
p-S166,S188-MDM2 [nucleoplasm]
(R-HSA-6793669)
0.697
5
UniProt:P04637 TP53
20
Unfolded TP53 [cytosol]
(R-HSA-6813797)
TP53 [cytosol]
(R-HSA-8869337)
PolyUb-TP53 [nucleoplasm]
(R-HSA-6782509)
polySUMO2,3-K386-TP53 [nucleoplasm]
(R-HSA-2997661)
TP53 F341C [nucleoplasm]
(R-HSA-9726318)
TP53 G334V [nucleoplasm]
(R-HSA-9726126)
TP53 L330H [nucleoplasm]
(R-HSA-9726124)
TP53 A347T [nucleoplasm]
(R-HSA-9726339)
TP53 R337C [nucleoplasm]
(R-HSA-9726118)
TP53 L344P [nucleoplasm]
(R-HSA-9726075)
TP53 L344R [nucleoplasm]
(R-HSA-9726073)
TP53 R337H [nucleoplasm]
(R-HSA-9726169)
TP53 R337P [nucleoplasm]
(R-HSA-9726168)
TP53 L330P [nucleoplasm]
(R-HSA-9726136)
TP53 L348S [nucleoplasm]
(R-HSA-9726366)
TP53 R337L [nucleoplasm]
(R-HSA-9726163)
TP53 K351E [nucleoplasm]
(R-HSA-9726258)
TP53 F338I [nucleoplasm]
(R-HSA-9726358)
TP53 R342P [nucleoplasm]
(R-HSA-9726101)
TP53 L330R [nucleoplasm]
(R-HSA-9726133)
0.676
6
UniProt:Q71RC2 LARP4
0.669
3
UniProt:Q8IZL8 PELP1
1
PELP1 [nucleoplasm]
(R-HSA-3826531)
0.664
4
UniProt:P62753 RPS6
4
RPS6 [nucleoplasm]
(R-HSA-6790606)
3OHR147-RPS6 [cytosol]
(R-HSA-9629876)
p-5S-RPS6 [cytosol]
(R-HSA-165727)
RPS6 [cytosol]
(R-HSA-72381)
0.65
3
UniProt:Q96CT7 CC124
0.649
8
UniProt:Q14690 PDCD11
1
PDCD11 [nucleoplasm]
(R-HSA-6790646)
0.643
3
UniProt:Q9BZE4 GTPB4
0.643
4
UniProt:P61313 RPL15
1
RPL15 [cytosol]
(R-HSA-72416)
0.643
3
UniProt:Q15397 PUM3
0.643
4
UniProt:P46781 RPS9
2
RPS9 [nucleoplasm]
(R-HSA-6790663)
RPS9 [cytosol]
(R-HSA-72387)
0.643
3
UniProt:P60228 EIF3E
1
EIF3E [cytosol]
(R-HSA-72552)
0.64
3
UniProt:B1Q2W9 B1Q2W9
0.639
8
UniProt:P24938 CORE5
0.623
4
UniProt:Q6UPD4 Q6UPD4
0.619
4
UniProt:Q14692 BMS1
1
BMS1 [nucleoplasm]
(R-HSA-6790720)
0.615
3
UniProt:Q9ULW3 ABT1
0.615
3
UniProt:P05386 RPLP1
1
RPLP1 [cytosol]
(R-HSA-72398)
0.615
3
UniProt:Q9NW13 RBM28
1
RBM28 [nucleoplasm]
(R-HSA-6791192)
0.615
3
UniProt:Q9NRX1 PNO1
2
PNO1 [nucleoplasm]
(R-HSA-6791540)
PNO1 [cytosol]
(R-HSA-6791509)
0.615
3
UniProt:Q9GZL7 WDR12
1
WDR12 [nucleoplasm]
(R-HSA-6791215)
0.615
3
UniProt:P42696 RBM34
0.615
4
UniProt:O15226 NKRF
0.615
3
UniProt:P13569 CFTR
17
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
CFTR [lysosomal membrane]
(R-HSA-5627279)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [endosome membrane]
(R-HSA-6782965)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
0.615
15
UniProt:P19338 NCL
3
NCL [plasma membrane]
(R-HSA-9836466)
NCL [macropinosome membrane]
(R-HSA-9837666)
NCL [nucleoplasm]
(R-HSA-6791213)
0.615
3
UniProt:Q9H6F5 CCD86
0.615
3
UniProt:Q9Y3C1 NOP16
0.615
4
UniProt:Q15050 RRS1
0.615
4
UniProt:O00566 MPHOSPH10
1
MPHOSPH10 [nucleoplasm]
(R-HSA-6790661)
0.615
3
UniProt:O15381 NVL
0.615
3
UniProt:O96028 NSD2
2
p-S102-WHSC1 [nucleoplasm]
(R-HSA-5682984)
WHSC1 [nucleoplasm]
(R-HSA-1183215)
0.615
3
UniProt:Q12788 TBL3
1
TBL3 [nucleoplasm]
(R-HSA-6790620)
0.615
3
UniProt:Q9Y3B9 RRP15
0.615
3
UniProt:Q6PK04 CC137
0.615
3
UniProt:Q01780 EXOSC10
1
EXOSC10 [nucleoplasm]
(R-HSA-6791547)
0.615
3
UniProt:Q96GQ7 DDX27
0.615
4
UniProt:Q9BYG3 MK67I
0.615
3
UniProt:O43159 RRP8
1
RRP8 [nucleoplasm]
(R-HSA-427524)
0.615
4
UniProt:Q9BQ39 DDX50
0.615
3
UniProt:P19525 EIF2AK2
5
p-EIF2AK2 [nucleoplasm]
(R-HSA-9836332)
SUMO-EIF2AK2 [cytosol]
(R-HSA-9834829)
ISG15-EIF2AK2 [cytosol]
(R-HSA-9833968)
p-EIF2AK2 [cytosol]
(R-HSA-9833834)
EIF2AK2 [cytosol]
(R-HSA-168699)
0.602
4
UniProt:Q9BZQ8 NIBA1
0.602
7
UniProt:Q9BXL5 HEMGN
0.599
7
UniProt:P49450 CENPA
2
CENPA [nucleoplasm]
(R-HSA-606322)
CENPA [cytosol]
(R-HSA-375317)
0.597
4
UniProt:P68951 NP
0.591
5
UniProt:P05549 TFAP2A
1
TFAP2A [nucleoplasm]
(R-HSA-8864280)
0.591
6
UniProt:O00505 KPNA3
2
KPNA3 [nucleoplasm]
(R-HSA-1176061)
KPNA3 [cytosol]
(R-HSA-1176070)
0.59
2
UniProt:P0DOE7 M
5
p-S95,T205-M [cytosol]
(R-RSY-9831678)
p-S95,T205-M [nucleoplasm]
(R-RSY-9831706)
M [nucleoplasm]
(R-RSY-9831711)
Nascent M [cytosol]
(R-RSY-9828672)
p-S95,T205-M [viral tegument]
(R-RSY-9836531)
0.576
3
UniProt:O14746 TERT
1
TERT [nucleoplasm]
(R-HSA-163076)
0.576
5
UniProt:O00629 KPNA4
2
KPNA4 [cytosol]
(R-HSA-1176066)
KPNA4 [nucleoplasm]
(R-HSA-1176058)
0.571
2
UniProt:Q9NX58 LYAR
0.564
2
UniProt:P63104 YWHAZ
2
YWHAZ [nucleoplasm]
(R-HSA-450469)
YWHAZ [cytosol]
(R-HSA-206099)
0.564
2
UniProt:Q96MT8 CEP63
1
CEP63 [cytosol]
(R-HSA-380267)
0.564
2
UniProt:Q8N726 CDKN2A
12
p14ARF [nucleoplasm]
(R-HSA-1629813)
p14ARF [cytosol]
(R-HSA-9645669)
p14ARF [mitochondrial matrix]
(R-HSA-9645695)
p14ARF R98L;R99S [cytosol]
(R-HSA-9645730)
p14ARF R82C [cytosol]
(R-HSA-9645750)
p14ARF R90H [cytosol]
(R-HSA-9645755)
p14ARF R88Q [cytosol]
(R-HSA-9645754)
p14ARF R87C [cytosol]
(R-HSA-9645759)
p14ARF R81G [cytosol]
(R-HSA-9645741)
p14ARF R98Q [cytosol]
(R-HSA-9645757)
p14ARF R99C [cytosol]
(R-HSA-9645756)
p14ARF V22Pfs*46 [cytosol]
(R-HSA-9646285)
0.564
2
UniProt:P49207 RPL34
1
RPL34 [cytosol]
(R-HSA-72458)
0.564
2
UniProt:Q92876 KLK6
0.556
3
UniProt:P10176 COX8A
1
COX8A [mitochondrial inner membrane]
(R-HSA-164313)
0.556
3
UniProt:Q86SE8-2 NPM2
0.556
5
UniProt:P03427 PB2
0.547
3
UniProt:Q8N3Z6 ZCHC7
0.536
2
UniProt:Q03164 KMT2A
6
KMT2A [cytosol]
(R-HSA-9818584)
KMT2A(2719-3969) [cytosol]
(R-HSA-9818590)
KMT2A(1-2718) [cytosol]
(R-HSA-9818597)
KMT2A [nucleoplasm]
(R-HSA-1183223)
KMT2A(1-2718) [nucleoplasm]
(R-HSA-9818591)
KMT2A(2719-3969) [nucleoplasm]
(R-HSA-9818593)
0.536
2
UniProt:P03372 ESR1
10
p-S118-ESR1 [nucleoplasm]
(R-HSA-9024210)
monoSUMO1-5K-ESR1 [nucleoplasm]
(R-HSA-4090302)
p-S167-ESR1 [nucleoplasm]
(R-HSA-9841867)
p-S167-ESR1 [cytosol]
(R-HSA-9841254)
Me260-ESR1 [cytosol]
(R-HSA-9632177)
PalmS-ESR1 [cytosol]
(R-HSA-9020974)
Me260-PalmS-ESR1 [plasma membrane]
(R-HSA-9637788)
PalmS-ESR1 [plasma membrane]
(R-HSA-9021057)
ESR1 [nucleoplasm]
(R-HSA-446168)
ESR1 [cytosol]
(R-HSA-9020968)
0.532
3
UniProt:O76021 RL1D1
0.527
2
UniProt:Q92522 H1X
0.527
2
UniProt:Q6PGP7 SKIC3
1
TTC37 [cytosol]
(R-HSA-8931541)
0.527
2
UniProt:P62263 RPS14
2
RPS14 [nucleoplasm]
(R-HSA-6790669)
RPS14 [cytosol]
(R-HSA-72333)
0.527
2
UniProt:Q07020 RPL18
1
RPL18 [cytosol]
(R-HSA-72420)
0.527
2
UniProt:Q9HCM4 EPB41L5
1
EPB41L5 [cytosol]
(R-HSA-6797564)
0.527
2
UniProt:Q99848 EBNA1BP2
1
EBNA1BP2 [nucleoplasm]
(R-HSA-8869325)
0.527
3
UniProt:P39019 RPS19
2
RPS19 [nucleoplasm]
(R-HSA-6798710)
RPS19 [cytosol]
(R-HSA-72343)
0.527
2
UniProt:Q6PKG0 LARP1
1
LARP1 [cytosol]
(R-HSA-9760421)
0.527
2
UniProt:P63220 RPS21
2
RPS21 [nucleoplasm]
(R-HSA-6798732)
RPS21 [cytosol]
(R-HSA-72351)
0.527
2
UniProt:Q1ED39 KNOP1
0.527
2
UniProt:P10636-8 MAPT
3
p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol]
(R-HSA-9836400)
p-S262,S356,S396-MAPT-8 [cytosol]
(R-HSA-9619521)
MAPT-8 [cytosol]
(R-HSA-9619519)
0.527
6
UniProt:P62241 RPS8
2
RPS8 [nucleoplasm]
(R-HSA-6791203)
RPS8 [cytosol]
(R-HSA-72385)
0.527
2
UniProt:P60866 RPS20
2
RPS20 [nucleoplasm]
(R-HSA-6798727)
RPS20 [cytosol]
(R-HSA-72349)
0.527
2
UniProt:Q5JTH9 RRP12
0.527
2
UniProt:Q6P158 DHX57
0.527
2
UniProt:Q49A26 GLYR1
0.527
3
UniProt:P49711 CTCF
1
CTCF [nucleoplasm]
(R-HSA-3782562)
0.527
2
UniProt:Q71UM5 RPS27L
2
RPS27L [nucleoplasm]
(R-HSA-6791197)
RPS27L [cytosol]
(R-HSA-8868849)
0.527
2
UniProt:Q14694 USP10
3
USP10 [nucleoplasm]
(R-HSA-3222218)
K63polyUb-USP10 [cytosol]
(R-HSA-6782986)
USP10 [cytosol]
(R-HSA-6782974)
0.527
2
UniProt:P62861 FAU
2
FAU [nucleoplasm]
(R-HSA-6798717)
FAU [cytosol]
(R-HSA-72371)
0.527
2
UniProt:Q969S3 ZN622
0.527
2
UniProt:P36578 RPL4
1
RPL4 [cytosol]
(R-HSA-72474)
0.527
3
UniProt:Q9GZR2 REXO4
0.527
3
UniProt:P46013 KI67
0.527
2
UniProt:O75818 RPP40
1
RPP40 [nucleoplasm]
(R-HSA-5696801)
0.527
3
UniProt:P19320 VCAM1
1
VCAM1 [plasma membrane]
(R-HSA-197834)
0.527
4
UniProt:P15880 RPS2
3
RPS2 [nucleoplasm]
(R-HSA-6790655)
Me2aR-RPS2 [cytosol]
(R-HSA-8879138)
RPS2 [cytosol]
(R-HSA-72347)
0.527
2
UniProt:P35251 RFC1
1
RFC1 [nucleoplasm]
(R-HSA-68435)
0.527
2
UniProt:Q9P287 BCCIP
0.527
2
UniProt:P62857 RPS28
2
RPS28 [nucleoplasm]
(R-HSA-6791202)
RPS28 [cytosol]
(R-HSA-72365)
0.527
2
UniProt:P61513 RPL37A
1
RPL37A [cytosol]
(R-HSA-72468)
0.527
2
UniProt:Q99613 EIF3C
1
EIF3C [cytosol]
(R-HSA-72550)
0.527
2
UniProt:P62280 RPS11
2
RPS11 [nucleoplasm]
(R-HSA-6791212)
RPS11 [cytosol]
(R-HSA-72327)
0.527
2
UniProt:Q9NXF1 TEX10
1
TEX10 [nucleoplasm]
(R-HSA-3826589)
0.527
3
UniProt:P62424 RPL7A
1
RPL7A [cytosol]
(R-HSA-72488)
0.527
2
UniProt:P22087 FBL
1
FBL [nucleoplasm]
(R-HSA-6790638)
0.527
2
UniProt:O00567 NOP56
2
NOP56 [nucleoplasm]
(R-HSA-6790696)
NOP56 [cytosol]
(R-HSA-391293)
0.527
2
UniProt:Q96PV0 SYNGAP1
1
SYNGAP1 [cytosol]
(R-HSA-5658217)
0.527
2
UniProt:Q7Z478 DHX29
0.527
2
UniProt:P35268 RPL22
1
RPL22 [cytosol]
(R-HSA-72428)
0.527
2
UniProt:Q06787 FMR1
0.527
3
UniProt:O75683 SURF6
0.527
3
UniProt:P62750 RPL23A
1
RPL23A [cytosol]
(R-HSA-72432)
0.527
3
UniProt:O76094 SRP72
1
SRP72 [cytosol]
(R-HSA-265069)
0.527
2
UniProt:Q8TDN6 BRX1
0.527
3
UniProt:Q8IY81 FTSJ3
1
FTSJ3 [nucleoplasm]
(R-HSA-6791507)
0.527
3
UniProt:Q14152 EIF3A
1
EIF3A [cytosol]
(R-HSA-72546)
0.527
2
UniProt:P50914 RPL14
1
RPL14 [cytosol]
(R-HSA-72414)
0.527
2
UniProt:O95707 POP4
1
POP4 [nucleoplasm]
(R-HSA-5696789)
0.527
3
UniProt:Q15477 SKIC2
1
SKIV2L [cytosol]
(R-HSA-391294)
0.527
2
UniProt:Q9UNX4 WDR3
1
WDR3 [nucleoplasm]
(R-HSA-6790724)
0.527
2
UniProt:P62906 RPL10A
1
RPL10A [cytosol]
(R-HSA-72404)
0.527
2
UniProt:Q96HI0 SENP5
1
SENP5 [nucleoplasm]
(R-HSA-2984297)
0.527
3
UniProt:Q8TDD1 DDX54
0.527
3
UniProt:P46783 RPS10
2
RPS10 [nucleoplasm]
(R-HSA-6798733)
RPS10 [cytosol]
(R-HSA-72325)
0.527
2
UniProt:P46782 RPS5
2
RPS5 [nucleoplasm]
(R-HSA-6791188)
RPS5 [cytosol]
(R-HSA-72379)
0.527
2
UniProt:O60264 SMARCA5
1
SMARCA5 [nucleoplasm]
(R-HSA-417140)
0.527
2
UniProt:Q9H7B2 RPF2
0.527
2
UniProt:Q13283 G3BP1
1
G3BP1 [cytosol]
(R-HSA-9729517)
0.527
2
UniProt:Q99575 POP1
1
POP1 [nucleoplasm]
(R-HSA-5696802)
0.527
2
UniProt:P78346 RPP30
1
RPP30 [nucleoplasm]
(R-HSA-5696779)
0.527
2
UniProt:Q7KZF4 SND1
2
SND1(1-593)-BRAF(381-766) fusion [cytosol]
(R-HSA-6802469)
SND1(1-593)-p-BRAF(381-766) fusion [cytosol]
(R-HSA-6802552)
0.527
2
UniProt:Q9Y4W2 LAS1L
1
LAS1L [nucleoplasm]
(R-HSA-6791521)
0.527
2
UniProt:Q6NW34 NEPRO
0.527
3
UniProt:P40429 RPL13A
2
p-RPL13A [cytosol]
(R-HSA-156829)
RPL13A [cytosol]
(R-HSA-72412)
0.527
2
UniProt:Q6DKI1 RL7L
0.527
3
UniProt:Q13547 HDAC1
2
HDAC1 [nucleoplasm]
(R-HSA-205021)
monoSUMO1-K444,K476-HDAC1 [nucleoplasm]
(R-HSA-4616030)
0.524
2
UniProt:Q98147 Q98147
0.524
2
UniProt:Q14684-1 RRP1B
0.512
4
UniProt:Q10570 CPSF1
1
CPSF1 [nucleoplasm]
(R-HSA-71989)
0.499
2
UniProt:Q9UQ80 PA2G4
2
PA2G4 [extracellular region]
(R-HSA-6806200)
PA2G4 [azurophil granule lumen]
(R-HSA-6799205)
0.491
3
UniProt:O14965 AURKA
6
SUMO1-K258-AURKA [cytosol]
(R-HSA-4655367)
p-T288-AURKA [nucleoplasm]
(R-HSA-6805089)
PolyUb-AURKA [cytosol]
(R-HSA-8854040)
AURKA [nucleoplasm]
(R-HSA-4655443)
AURKA [cytosol]
(R-HSA-174254)
p-T288-AURKA [cytosol]
(R-HSA-2574832)
0.489
3
UniProt:Q8N8A6 DDX51
0.483
2
UniProt:Q8NHQ9 DDX55
0.483
3
UniProt:Q9NY61 AATF
1
AATF [cytosol]
(R-HSA-205071)
0.483
2
UniProt:Q9BXY0 MAK16
0.483
3
UniProt:Q68D10 SPT2
0.483
2
UniProt:Q8N9T8 KRI1
0.483
2
UniProt:P48634 PRC2A
0.483
2
UniProt:Q96SB4 SRPK1
2
SRPK1 [nucleoplasm]
(R-HSA-9821984)
SRPK1 [cytosol]
(R-HSA-9729349)
0.483
2
UniProt:Q08J23 NSUN2
1
NSUN2 [nucleoplasm]
(R-HSA-6782382)
0.483
2
UniProt:Q9HCK8 CHD8
1
CHD8 [nucleoplasm]
(R-HSA-3221598)
0.483
2
UniProt:P36873 PPP1CC
1
PPP1CC [cytosol]
(R-HSA-163443)
0.483
2
UniProt:Q9BRJ6 CG050
0.483
2
UniProt:P19784 CSNK2A2
2
CSNK2A2 [nucleoplasm]
(R-HSA-6805065)
CSNK2A2 [cytosol]
(R-HSA-201721)
0.483
2
UniProt:O95793 STAU1
0.483
2
UniProt:Q9H501 ESF1
0.483
2
UniProt:Q6MZP7 LIN54
1
LIN54 [nucleoplasm]
(R-HSA-389103)
0.483
2
UniProt:Q8NEJ9 NGDN
0.483
2
UniProt:Q9NZM5 NOP53
0.483
3
UniProt:Q9NVU7 SDA1
0.483
2
UniProt:P35250 RFC2
1
RFC2 [nucleoplasm]
(R-HSA-68433)
0.483
2
UniProt:P11388 TOP2A
3
TOP2A [nucleoplasm]
(R-HSA-1362276)
polySUMO2,3-TOP2A [nucleoplasm]
(R-HSA-4641298)
monoSUMO1-K-TOP2A [nucleoplasm]
(R-HSA-4641367)
0.483
2
UniProt:Q9H6Y2 WDR55
0.483
2
UniProt:Q9BSC4 NOL10
0.483
2
UniProt:Q5QJE6 TDIF2
0.483
2
UniProt:Q9ULJ3 ZBT21
0.483
2
UniProt:Q96B26 EXOSC8
2
EXOSC8 [nucleoplasm]
(R-HSA-6791571)
EXOSC8 [cytosol]
(R-HSA-429912)
0.483
2
UniProt:Q8IY37 DHX37
1
DHX37 [nucleoplasm]
(R-HSA-6790668)
0.483
2
UniProt:Q14781 CBX2
1
CBX2 [nucleoplasm]
(R-HSA-389110)
0.483
2
UniProt:Q2TB10 ZN800
0.483
3
UniProt:Q96L73 NSD1
1
NSD1 [nucleoplasm]
(R-HSA-1183232)
0.483
2
UniProt:Q13206 DDX10
0.483
2
UniProt:O95639 CPSF4
1
CPSF4 [nucleoplasm]
(R-HSA-169104)
0.483
2
UniProt:Q9H9L3 ISG20L2
1
ISG20L2 [nucleoplasm]
(R-HSA-6799476)
0.483
2
UniProt:Q9NQZ2 UTP3
1
UTP3 [nucleoplasm]
(R-HSA-6790637)
0.483
2
UniProt:Q02880 TOP2B
2
monoSUMO1-K-TOP2B [nucleoplasm]
(R-HSA-4641297)
TOP2B [nucleoplasm]
(R-HSA-4641359)
0.483
2
UniProt:O95625 ZBT11
0.483
2
UniProt:Q9BRD0 BUD13
1
BUD13 [nucleoplasm]
(R-HSA-9769522)
0.483
3
UniProt:Q86U86 PBRM1
1
PBRM1 [nucleoplasm]
(R-HSA-389254)
0.483
2
UniProt:Q13895 BYSL
2
BYSL [nucleoplasm]
(R-HSA-6791526)
BYSL [cytosol]
(R-HSA-6791518)
0.483
2
UniProt:Q8WYP5 AHCTF1
1
AHCTF1 [cytosol]
(R-HSA-376244)
0.483
2
UniProt:Q03188 CENPC
2
CENPC [nucleoplasm]
(R-HSA-5633512)
CENPC1 [cytosol]
(R-HSA-375292)
0.483
2
UniProt:Q9HC52 CBX8
1
CBX8 [nucleoplasm]
(R-HSA-389117)
0.483
2
UniProt:Q9Y2R4 DDX52
1
DDX52 [nucleoplasm]
(R-HSA-6790703)
0.483
2
UniProt:Q9Y4C8 RBM19
0.483
2
UniProt:Q86VM9 ZCH18
0.483
3
UniProt:Q14966 ZNF638
1
ZNF638 [nucleoplasm]
(R-HSA-8939429)
0.483
2
UniProt:Q12789 GTF3C1
1
GTF3C1 [nucleoplasm]
(R-HSA-83697)
0.483
2
UniProt:Q9BVJ6 UTP14A
1
UTP14A [nucleoplasm]
(R-HSA-6790695)
0.483
2
UniProt:O00541 PES1
1
PES1 [nucleoplasm]
(R-HSA-6791207)
0.483
2
UniProt:Q9Y676 MRPS18B
1
MRPS18B [mitochondrial inner membrane]
(R-HSA-5368234)
0.483
2
UniProt:P78362 SRPK2
1
SRPK2 [cytosol]
(R-HSA-9729332)
0.483
2
UniProt:P20700 LMNB1
8
LMNB1 [nucleoplasm]
(R-HSA-264867)
LMNB1(1-231) [nuclear envelope]
(R-HSA-352244)
LMNB1(232-586) [nuclear envelope]
(R-HSA-352248)
LMNB1 [cytosol]
(R-HSA-2995384)
p-S395, S405-LMNB1 [nucleoplasm]
(R-HSA-5228738)
p-S23, S395, S405-LMNB1 [nucleoplasm]
(R-HSA-5229018)
LMNB1(2-586) [nuclear envelope]
(R-HSA-912402)
p-S23,S393-LMNB1 [nucleoplasm]
(R-HSA-8868341)
0.483
2
UniProt:Q9NUL3 STAU2
0.483
2
UniProt:Q03701 CEBPZ
0.483
2
UniProt:Q9NQT5 EXOSC3
2
EXOSC3 [nucleoplasm]
(R-HSA-6791572)
EXOSC3 [cytosol]
(R-HSA-430017)
0.483
2
UniProt:Q8NDF8 PAPD5
0.483
3
UniProt:Q99459 CDC5L
1
CDC5L [nucleoplasm]
(R-HSA-5420887)
0.483
2
UniProt:Q8NFW8 CMAS
1
CMAS [nucleoplasm]
(R-HSA-4085417)
0.483
2
UniProt:P78344 EIF4G2
1
EIF4G2 [cytosol]
(R-HSA-1678826)
0.483
2
UniProt:P78345 RPP38
1
RPP38 [nucleoplasm]
(R-HSA-5696791)
0.483
3
UniProt:Q9BTD8 RBM42
1
RBM42 [nucleoplasm]
(R-HSA-9769526)
0.483
2
UniProt:Q9UIG0 BAZ1B
1
BAZ1B [nucleoplasm]
(R-HSA-417153)
0.483
2
UniProt:Q04637 EIF4G1
2
p-S1108,S1148,S1192-EIF4G1 [cytosol]
(R-HSA-165762)
EIF4G1 [cytosol]
(R-HSA-72584)
0.483
2
UniProt:Q8IUH3 RBM45
0.462
2
UniProt:P11387 TOP1
2
monoSUMO1-K117-TOP1 [nucleoplasm]
(R-HSA-4641364)
TOP1 [nucleoplasm]
(R-HSA-4641363)
0.462
3
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