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NELFE [nucleoplasm]
Stable Identifier
R-HSA-62907
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
RDBP, RD protein, Negative elongation factor E, NELF-E
Locations in the PathwayBrowser for interactor UniProt:P14373 TRIM27
Expand all
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
RNA Polymerase II Pre-transcription Events (Homo sapiens)
Formation of NELF complex (Homo sapiens)
NELFE [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:P18615 NELFE
Gene Names
NELFE, RD, RDBP
Chain
chain:1-380
Reference Genes
BioGPS Gene:7936 NELFE
COSMIC (genes):NELFE NELFE
CTD Gene:7936 NELFE
dbSNP Gene:7936 NELFE
ENSEMBL:ENSG00000204356 NELFE
ENSEMBL:ENSG00000204356.14 NELFE
ENSEMBL:ENSG00000206268.11 NELFE
ENSEMBL:ENSG00000206357.11 NELFE
ENSEMBL:ENSG00000229363.9 NELFE
ENSEMBL:ENSG00000231044.10 NELFE
ENSEMBL:ENSG00000233801.9 NELFE
HGNC:13974 NELFE
KEGG Gene (Homo sapiens):7936 NELFE
Monarch:7936 NELFE
NCBI Gene:7936 NELFE
OMIM:154040 NELFE
UCSC:P18615 NELFE
Reference Transcript
RefSeq:NM_002904.5 NELFE
Other Identifiers
11744211_a_at
11744949_a_at
17017575
17029432
17032218
17036925
17039668
17042173
209219_PM_at
209219_at
2948763
2948764
2948765
2948766
2948768
2948769
2948770
2948771
2948772
2948773
2948775
2948776
2948777
2948778
2948780
2948781
2948782
41407_at
7936
8125204
8178686
8179913
A_23_P122545
A_24_P849628
GE79511
GO:0000122
GO:0000785
GO:0003676
GO:0003682
GO:0003723
GO:0003729
GO:0005515
GO:0005634
GO:0005654
GO:0005694
GO:0005886
GO:0006351
GO:0006355
GO:0016604
GO:0023052
GO:0032021
GO:0034244
GO:0036211
GO:0043226
GO:0045944
GO:0051179
GO:0051571
GO:0070374
HMNXSV003000966
ILMN_1765532
L03411_s_at
PH_hs_0019794
TC06001552.hg
TC6_cox_hap2000180.hg
TC6_dbb_hap3000169.hg
TC6_mcf_hap5000155.hg
TC6_qbl_hap6000170.hg
TC6_ssto_hap7000148.hg
X99296_xpt1_at
g190973_3p_at
Participates
as an input of
Formation of NELF complex (Homo sapiens)
as a component of
NELF complex [nucleoplasm] (Homo sapiens)
Other forms of this molecule
p-NELFE [nucleoplasm]
Inferred To
Ghost homologue of NELFE [nucleoplasm]
(Caenorhabditis elegans)
Ghost homologue of NELFE [nucleoplasm]
(Dictyostelium discoideum)
Ghost homologue of NELFE [nucleoplasm]
(Saccharomyces cerevisiae)
Ghost homologue of NELFE [nucleoplasm]
(Schizosaccharomyces pombe)
Nelfe [nucleoplasm]
(Mus musculus)
Nelfe [nucleoplasm]
(Rattus norvegicus)
NELFE [nucleoplasm]
(Bos taurus)
NELFE [nucleoplasm]
(Canis familiaris)
NELFE [nucleoplasm]
(Danio rerio)
NELFE [nucleoplasm]
(Gallus gallus)
NELFE [nucleoplasm]
(Sus scrofa)
Nelf-E [nucleoplasm]
(Drosophila melanogaster)
nelfe [nucleoplasm]
(Xenopus tropicalis)
Cross References
RefSeq
NP_002895.3
OpenTargets
ENSG00000204356
HPA
ENSG00000204356-NELFE
GeneCards
P18615
Ensembl
ENSP00000372834
,
ENST00000429857
,
ENSP00000372660
,
ENSG00000229363
,
ENSP00000393005
,
ENSP00000388400
,
ENSP00000394879
,
ENST00000457397
,
ENST00000375425
,
ENSG00000233801
,
ENSG00000204356
,
ENSG00000231044
,
ENSG00000206357
,
ENST00000383343
,
ENST00000448628
,
ENSG00000206268
,
ENSP00000364574
,
ENST00000375429
,
ENSP00000364578
,
ENST00000444811
,
ENST00000383174
,
ENSP00000403623
PRO
P18615
Pharos - Targets
P18615
PDB
2JX2
,
1X5P
,
2BZ2
,
5OOB
,
7YCX
,
6GML
Interactors (10)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q8WX92 NELFB
3
NELFB [nucleoplasm]
(R-HSA-112427)
NELFB [mitochondrial outer membrane]
(R-HSA-9603553)
NELFB [cytosol]
(R-HSA-9603526)
0.873
7
UniProt:Q9H3P2 NELFA
1
NELFA [nucleoplasm]
(R-HSA-112426)
0.758
7
UniProt:Q8IXH7-4 NELFCD
0.643
3
UniProt:P52298 NCBP2
2
NCBP2 [nucleoplasm]
(R-HSA-51463)
NCBP2 [cytosol]
(R-HSA-162458)
0.643
4
UniProt:Q2TAC2 CCD57
0.556
3
UniProt:Q63ZY3 KANK2
0.556
3
UniProt:P14373 TRIM27
2
TRIM27 [nucleoplasm]
(R-HSA-2997690)
TRIM27 [cytosol]
(R-HSA-8851002)
0.556
3
UniProt:Q8WX92-2 Q8WX922
0.556
7
UniProt:Q5JR59 MTUS2
0.556
3
UniProt:Q09161 NCBP1
2
NCBP1 [nucleoplasm]
(R-HSA-51469)
NCBP1 [cytosol]
(R-HSA-162459)
0.527
4
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