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What is Reactome ?
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ERCC3 [nucleoplasm]
Stable Identifier
R-HSA-67439
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
XPB protein , ERCC-3, TFIIH basal transcription factor complex helicase XPB subunit (EC 3.6.1.-) (Basic transcription factor 2 89 kDa subunit) (BTF2-p89) (TFIIH 89 kDa subunit) (DNA-repair protein complementing XP-B cells) (Xeroderma pigmentosum group B complementing protein) (DNA excision repair protein ERCC-3), TFIIH basal transcription factor complex helicase XPB subunit , Basic transcription factor 2 89 kDa subunit, BTF2-p89, TFIIH 89 kDa subunit, DNA-repair protein complementing XP-B cells, Xeroderma pigmentosum group B complementing protein, DNA excision repair protein ERCC-3
Locations in the PathwayBrowser
Expand all
DNA Repair (Homo sapiens)
Nucleotide Excision Repair (Homo sapiens)
Global Genome Nucleotide Excision Repair (GG-NER) (Homo sapiens)
Dual Incision in GG-NER (Homo sapiens)
3'-incision of DNA by ERCC5 (XPG) in GG-NER (Homo sapiens)
GG-NER incision complex:5'-incised damaged DNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
TFIIH Core [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
TFIIH Core [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
5'- incision of DNA by ERCC1:ERCC4 in GG-NER (Homo sapiens)
GG-NER incision complex:5'-incised damaged DNA [nucleoplasm] (Homo sapiens)
TFIIH Core [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
GG-NER incision complex:Open bubble dsDNA [nucleoplasm] (Homo sapiens)
GG-NER pre-incision complex:Open bubble-dsDNA [nucleoplasm] (Homo sapiens)
Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Homo sapiens)
TFIIH Core [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
DNA polymerases delta, epsilon or kappa bind the GG-NER site (Homo sapiens)
GG-NER incision complex:5'-incised damaged DNA [nucleoplasm] (Homo sapiens)
TFIIH Core [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
GG-NER incision complex:5'-incised damaged DNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
TFIIH Core [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Formation of Incision Complex in GG-NER (Homo sapiens)
Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in GG-NER (Homo sapiens)
GG-NER incision complex:Open bubble dsDNA [nucleoplasm] (Homo sapiens)
GG-NER pre-incision complex:Open bubble-dsDNA [nucleoplasm] (Homo sapiens)
Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Homo sapiens)
TFIIH Core [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
GG-NER pre-incision complex:Open bubble-dsDNA [nucleoplasm] (Homo sapiens)
Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Homo sapiens)
TFIIH Core [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
CHD1L is recruited to GG-NER site (Homo sapiens)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Homo sapiens)
TFIIH Core [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2:CHD1L [nucleoplasm] (Homo sapiens)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Homo sapiens)
TFIIH Core [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA (Homo sapiens)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2:CHD1L [nucleoplasm] (Homo sapiens)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Homo sapiens)
TFIIH Core [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Ub:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2:CHD1L [nucleoplasm] (Homo sapiens)
TFIIH Core [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Formation of the pre-incision complex in GG-NER (Homo sapiens)
GG-NER pre-incision complex:Open bubble-dsDNA [nucleoplasm] (Homo sapiens)
Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Homo sapiens)
TFIIH Core [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Homo sapiens)
TFIIH Core [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
RNF111 ubiquitinates SUMOylated XPC (Homo sapiens)
Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Homo sapiens)
TFIIH Core [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Ub,SUMO:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Homo sapiens)
TFIIH Core [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Recruitment of XPA and release of CAK (Homo sapiens)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Homo sapiens)
TFIIH Core [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
SUMOylation of XPC (Homo sapiens)
Ub,SUMO:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1, PAR-PARP2:CHD1L [nucleoplasm] (Homo sapiens)
TFIIH Core [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Ub:XPC:RAD23:CETN2:Open bubble-dsDNA:PAR-UV-DDB:TFIIH Core:XPA:PAR-PARP1,PAR-PARP2:CHD1L [nucleoplasm] (Homo sapiens)
TFIIH Core [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
TFIIH binds GG-NER site to form a verification complex (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH:PAR-PARP1,PAR-PARP2 [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Transcription-Coupled Nucleotide Excision Repair (TC-NER) (Homo sapiens)
Dual incision in TC-NER (Homo sapiens)
3' incision by ERCC5 (XPG) in TC-NER (Homo sapiens)
TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
TC-NER post-incision complex:incised DNA without lesion:trimmed nascent mRNA:PCNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER (Homo sapiens)
TC-NER incision complex [nucleoplasm] (Homo sapiens)
TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Homo sapiens)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Homo sapiens)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Homo sapiens)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6 [nucleoplasm] (Homo sapiens)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
TC-NER incision complex:5'-incised damaged DNA:trimmed nascent mRNA [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER (Homo sapiens)
TC-NER incision complex [nucleoplasm] (Homo sapiens)
TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Homo sapiens)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Homo sapiens)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Homo sapiens)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6 [nucleoplasm] (Homo sapiens)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Homo sapiens)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Homo sapiens)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Homo sapiens)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6 [nucleoplasm] (Homo sapiens)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
DNA polymerases delta, epsilon or kappa bind the TC-NER site (Homo sapiens)
TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
TC-NER incision complex:5'-incised damaged DNA:trimmed nascent mRNA [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
ERCC2-facilitated RNA Pol II backtracking in TC-NER (Homo sapiens)
TC-NER pre-incision complex [nucleoplasm] (Homo sapiens)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Homo sapiens)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6 [nucleoplasm] (Homo sapiens)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
TC-NER pre-incision complex:Partially open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Homo sapiens)
Ubiquitinated,hyperphosphorylated RNA Pol II:Partially open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Homo sapiens)
Ubiquitinated,hyperphosphorylated RNA Pol II:Partially open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6 [nucleoplasm] (Homo sapiens)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
ERCC3-facilitated RNA Pol II backtracking in TC-NER (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Homo sapiens)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Homo sapiens)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6 [nucleoplasm] (Homo sapiens)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
TC-NER pre-incision complex:Partially open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Homo sapiens)
Ubiquitinated,hyperphosphorylated RNA Pol II:Partially open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Homo sapiens)
Ubiquitinated,hyperphosphorylated RNA Pol II:Partially open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6 [nucleoplasm] (Homo sapiens)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
ERCC5 and RPA bind TC-NER site (Homo sapiens)
TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Homo sapiens)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Homo sapiens)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Homo sapiens)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6 [nucleoplasm] (Homo sapiens)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Homo sapiens)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Homo sapiens)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6 [nucleoplasm] (Homo sapiens)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Formation of TC-NER Pre-Incision Complex (Homo sapiens)
Active RNA Pol II complex transcribes lesion-containing DNA template (Homo sapiens)
Damaged dsDNA with open transcription bubble:Hyperphosphorylated RNA Pol II:TFIIH [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Assembly of the pre-incision complex in TC-NER (Homo sapiens)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Homo sapiens)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6 [nucleoplasm] (Homo sapiens)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1:UVSSA:USP7:XAB2 complex:XPA:TCEA1:HMGN1:EP300 [nucleoplasm] (Homo sapiens)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Homo sapiens)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6 [nucleoplasm] (Homo sapiens)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
ERCC6 binds stalled RNA Pol II (Homo sapiens)
Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6 [nucleoplasm] (Homo sapiens)
Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
ERCC8 (CSA) binds stalled RNA Pol II (Homo sapiens)
Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6 [nucleoplasm] (Homo sapiens)
Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Homo sapiens)
Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6 [nucleoplasm] (Homo sapiens)
Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II (Homo sapiens)
Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Homo sapiens)
Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6 [nucleoplasm] (Homo sapiens)
Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Homo sapiens)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6 [nucleoplasm] (Homo sapiens)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
RNA Pol II initiates transcription from damaged DNA template (Homo sapiens)
Damaged dsDNA with open transcription bubble:Hyperphosphorylated RNA Pol II:TFIIH [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
UVSSA:USP7 deubiquitinates ERCC6 (Homo sapiens)
TC-NER pre-incision complex [nucleoplasm] (Homo sapiens)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Homo sapiens)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6 [nucleoplasm] (Homo sapiens)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1:UVSSA:USP7:XAB2 complex:XPA:TCEA1:HMGN1:EP300 [nucleoplasm] (Homo sapiens)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm] (Homo sapiens)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6 [nucleoplasm] (Homo sapiens)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Gap-filling DNA repair synthesis and ligation in TC-NER (Homo sapiens)
Ligation of newly synthesized repair patch to incised DNA in TC-NER (Homo sapiens)
TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
TC-NER post-incision complex:dsDNA with transcription bubble [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER (Homo sapiens)
TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
TC-NER post-incision complex:incised DNA without lesion:trimmed nascent mRNA:PCNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Recovery of RNA synthesis after TC-NER (Homo sapiens)
TC-NER post-incision complex:dsDNA with transcription bubble [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
HIV Infection (Homo sapiens)
HIV Life Cycle (Homo sapiens)
Late Phase of HIV Life Cycle (Homo sapiens)
Transcription of the HIV genome (Homo sapiens)
Fall Back to Closed Pre-initiation Complex (Homo sapiens)
HIV-1 closed pre-initiation complex [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
HIV-1 open pre-initiation complex [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Formation of HIV elongation complex in the absence of HIV Tat (Homo sapiens)
Recruitment of elongation factors to form HIV-1 elongation complex (Homo sapiens)
HIV-1 elongation complex [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
HIV Promoter Opening: First Transition (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
HIV-1 closed pre-initiation complex [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
HIV-1 open pre-initiation complex [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
HIV Transcription Elongation (Homo sapiens)
Formation of the HIV-1 Early Elongation Complex (Homo sapiens)
Hypophosphorylation of RNA Pol II CTD by FCP1P protein (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Tat-mediated elongation of the HIV-1 transcript (Homo sapiens)
Addition of nucleotides leads to HIV-1 transcript elongation (Homo sapiens)
HIV-1 elongation complex containing Tat [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Formation of HIV-1 elongation complex containing HIV-1 Tat (Homo sapiens)
Recruitment of elongation factors to form HIV-1 elongation complex (Homo sapiens)
HIV-1 elongation complex containing Tat [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
HIV Transcription Initiation (Homo sapiens)
Abortive HIV-1 initiation after formation of the first phosphodiester bond (Homo sapiens)
HIV-1 transcription complex [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
NTP binds active site of RNA Polymerase II in HIV-1 open pre-initiation complex (Homo sapiens)
HIV-1 initiation complex [nucleoplasm] (Homo sapiens)
RNA Polymearse II:NTP:TFIIF complex [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
HIV-1 open pre-initiation complex [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Newly formed phosphodiester bond stabilized and PPi released (Homo sapiens)
HIV-1 initiation complex with phosphodiester-PPi intermediate [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
HIV-1 transcription complex [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Nucleophillic attack by 3'-hydroxyl oxygen of nascent HIV-1 transcript on the Alpha phosphate of NTP (Homo sapiens)
HIV-1 initiation complex [nucleoplasm] (Homo sapiens)
RNA Polymearse II:NTP:TFIIF complex [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
HIV-1 initiation complex with phosphodiester-PPi intermediate [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection (Homo sapiens)
Activation of GT (Homo sapiens)
RNA Pol II with phosphorylated CTD: CE complex [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
RNA Pol II with phosphorylated CTD: CE complex with activated GT [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Extrusion of 5'-end of 30 nt long HIV-1 transcript through the pore in Pol II complex (Homo sapiens)
HIV-1 transcription complex containing extruded transcript to +30 [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
HIV-1 transcription complex containing transcript to +30 [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Phosphorylation (Ser5) of RNA pol II CTD (Homo sapiens)
HIV-1 transcription complex containing extruded transcript to +30 [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
HIV-1 transcription complex with (ser5) phosphorylated CTD containing extruded transcript to +30 [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Pol II transcription complex containing extruded transcript to +30 [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
RNA Polymerase II CTD (phosphorylated) binds to CE (Homo sapiens)
HIV-1 transcription complex with (ser5) phosphorylated CTD containing extruded transcript to +30 [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
RNA Pol II with phosphorylated CTD: CE complex [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) (Homo sapiens)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
RNA Pol II with phosphorylated CTD: CE complex with activated GT [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
RNA Polymerase II HIV Promoter Escape (Homo sapiens)
Abortive HIV-1 Initiation After Second Transition (Homo sapiens)
HIV-1 transcription complex containing 4-9 nucleotide long transcript [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Abortive HIV-1 Initiation Before Second Transition (Homo sapiens)
HIV-1 Promoter Escape Complex [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Addition of nucleotides 10 and 11 on the growing HIV-1 transcript: Third Transition (Homo sapiens)
HIV-1 transcription complex containing 11 nucleotide long transcript [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
HIV-1 transcription complex containing 9 nucleotide long transcript [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Addition of nucleotides 5 through 9 on the growing HIV-1 transcript (Homo sapiens)
HIV-1 transcription complex containing 4 nucleotide long transcript [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
HIV-1 transcription complex containing 9 nucleotide long transcript [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Addition of nucleotides between position +11 and +30 on HIV-1 transcript (Homo sapiens)
HIV-1 transcription complex containing 11 nucleotide long transcript [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
HIV-1 transcription complex containing transcript to +30 [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Addition of the fourth nucleotide on the nascent HIV-1 transcript: Second Transition (Homo sapiens)
HIV-1 transcription complex containing 3 nucleotide long transcript [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
HIV-1 transcription complex containing 4 nucleotide long transcript [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Addition of the third nucleotide on the nascent HIV-1 transcript (Homo sapiens)
HIV-1 transcription complex [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
HIV-1 transcription complex containing 3 nucleotide long transcript [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Unwinding of DNA for the nascent HIV-1 transcript (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
HIV-1 transcription complex [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Unwinding of DNA for the nascent HIV-1 transcript: Second Transition (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
HIV-1 transcription complex containing 3 nucleotide long transcript [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Gene expression (Transcription) (Homo sapiens)
Epigenetic regulation of gene expression (Homo sapiens)
Negative epigenetic regulation of rRNA expression (Homo sapiens)
NoRC negatively regulates rRNA expression (Homo sapiens)
Transcription of intergenic spacer of the rRNA gene (Homo sapiens)
RNA Polymerase I promoter escape complex [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
RNA Polymerase I Transcription (Homo sapiens)
RNA Polymerase I Promoter Clearance (Homo sapiens)
RNA Polymerase I Promoter Escape (Homo sapiens)
Elongation of pre-rRNA transcript (Homo sapiens)
RNA Polymerase I promoter escape complex [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Loss of Rrn3 from RNA Polymerase I promoter escape complex (Homo sapiens)
RNA Polymerase I Transcription Initiation complex [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
RNA Polymerase I promoter escape complex [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
RNA Polymerase I Transcription Initiation (Homo sapiens)
Recruitment of Active RNA Polymerase I to SL1:phos.UBF-1:rDNA Promoter (Homo sapiens)
RNA Polymerase I Transcription Initiation complex [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
RNA Polymerase I Transcription Termination (Homo sapiens)
Dissociation of PTRF:Polymerase I/Nascent Pre rRNA Complex:TTF-I:Sal Box (Homo sapiens)
PTRF:Polymerase I/Nascent Pre rRNA Complex:TTF-I:Sal Box [nucleoplasm] (Homo sapiens)
RNA Polymerase I:rRNATranscript:TTF-1:Sal Box Complex [nucleoplasm] (Homo sapiens)
RNA Polymerase I promoter escape complex [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
RNA Polymerase I promoter escape complex [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
PTRF Binds the Polymerase I Transcription Complex/Nascent Pre rRNA Complex paused at the TTF-I:Sal Box (Homo sapiens)
PTRF:Polymerase I/Nascent Pre rRNA Complex:TTF-I:Sal Box [nucleoplasm] (Homo sapiens)
RNA Polymerase I:rRNATranscript:TTF-1:Sal Box Complex [nucleoplasm] (Homo sapiens)
RNA Polymerase I promoter escape complex [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
RNA Polymerase I:rRNATranscript:TTF-1:Sal Box Complex [nucleoplasm] (Homo sapiens)
RNA Polymerase I promoter escape complex [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Polymerase I Transcription Complex/Nascent Pre rRNA Complex pauses at the TTF-I:Sal Box (Homo sapiens)
RNA Polymerase I promoter escape complex [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
RNA Polymerase I:rRNATranscript:TTF-1:Sal Box Complex [nucleoplasm] (Homo sapiens)
RNA Polymerase I promoter escape complex [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional Regulation by TP53 (Homo sapiens)
TP53 Regulates Transcription of DNA Repair Genes (Homo sapiens)
CCNK:CDK12 binds RNA Pol II at DNA repair genes (Homo sapiens)
CCNK:CDK12:Elongation Complex at DNA Repair Genes [nucleoplasm] (Homo sapiens)
Elongation Complex at DNA Repair Genes [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Elongation Complex at DNA Repair Genes [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
CDK12 phosphorylates RNA Pol II CTD at DNA repair genes (Homo sapiens)
CCNK:CDK12:CDK12-Phosphorylated Elongation Complex at DNA repair genes [nucleoplasm] (Homo sapiens)
CDK12-Phosphorylated Elongation Complex [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
CCNK:CDK12:Elongation Complex at DNA Repair Genes [nucleoplasm] (Homo sapiens)
Elongation Complex at DNA Repair Genes [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
CDK12 stimulates expression of DNA repair genes (Homo sapiens)
CCNK:CDK12:CDK12-Phosphorylated Elongation Complex at DNA repair genes [nucleoplasm] (Homo sapiens)
CDK12-Phosphorylated Elongation Complex [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
RNA Pol II CTD phosphorylation and interaction with CE (Homo sapiens)
Activation of GT (Homo sapiens)
RNA Pol II with phosphorylated CTD: CE complex [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
RNA Pol II with phosphorylated CTD: CE complex with activated GT [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Extrusion of 5'-end of 30 nt long transcript through the pore in Pol II complex (Homo sapiens)
Pol II transcription complex containing extruded transcript to +30 [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Pol II transcription complex containing transcript to +30 [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Phosphorylation (Ser5) of RNA pol II CTD (Homo sapiens)
Pol II transcription complex containing extruded transcript to +30 [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Pol II transcription complex with (ser5) phosphorylated CTD containing extruded transcript to +30 [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
RNA Polymerase II CTD (phosphorylated) binds to CE (Homo sapiens)
Pol II transcription complex with (ser5) phosphorylated CTD containing extruded transcript to +30 [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
RNA Pol II with phosphorylated CTD: CE complex [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) (Homo sapiens)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
RNA Pol II with phosphorylated CTD: CE complex with activated GT [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
RNA Polymerase II Pre-transcription Events (Homo sapiens)
Abortive Initiation After Second Transition (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
pol II transcription complex containing 4-9 nucleotide long transcript [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Abortive Initiation Before Second Transition (Homo sapiens)
Pol II Promoter Escape Complex [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Abortive initiation after formation of the first phosphodiester bond (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
pol II transcription complex [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Fall Back to Closed Pre-initiation Complex (Homo sapiens)
pol II closed pre-initiation complex [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
pol II open pre-initiation complex [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
RNA Polymerase II Transcription Elongation (Homo sapiens)
Addition of nucleotides leads to transcript elongation (Homo sapiens)
Elongation complex [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Formation of RNA Pol II elongation complex (Homo sapiens)
Recruitment of elongation factors to form elongation complex (Homo sapiens)
Elongation complex [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Formation of the Early Elongation Complex (Homo sapiens)
Hypophosphorylation of RNA Pol II CTD by FCP1P protein (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
RNA Polymerase II Transcription Initiation And Promoter Clearance (Homo sapiens)
RNA Polymerase II Promoter Escape (Homo sapiens)
Addition of Nucleotides 5 through 9 on the growing Transcript (Homo sapiens)
pol II transcription complex containing 4 nucleotide long transcript [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
pol II transcription complex containing 9 nucleotide long transcript [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Addition of nucleotides 10 and 11 on the growing transcript: Third Transition (Homo sapiens)
pol II transcription complex containing 11 nucleotide long transcript [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
pol II transcription complex containing 9 nucleotide long transcript [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Addition of nucleotides between position +11 and +30 (Homo sapiens)
Pol II transcription complex containing transcript to +30 [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
pol II transcription complex containing 11 nucleotide long transcript [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Addition of the fourth nucleotide on the Nascent Transcript: Second Transition (Homo sapiens)
pol II transcription complex containing 3 Nucleotide long transcript [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
pol II transcription complex containing 4 nucleotide long transcript [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Addition of the third nucleotide on the nascent transcript (Homo sapiens)
pol II transcription complex [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
pol II transcription complex containing 3 Nucleotide long transcript [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Unwinding DNA for the nascent transcript (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
pol II transcription complex [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Unwinding of DNA for the Nascent Transcript: Second Transition (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
pol II transcription complex containing 3 Nucleotide long transcript [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
RNA Polymerase II Promoter Opening: First Transition (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
pol II closed pre-initiation complex [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
pol II open pre-initiation complex [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
RNA Polymerase II Transcription Initiation (Homo sapiens)
NTP Binds Active Site of RNA Polymerase II (Homo sapiens)
Pol II initiation complex [nucleoplasm] (Homo sapiens)
RNA Polymearse II:NTP:TFIIF complex [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
pol II open pre-initiation complex [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Newly Formed Phosphodiester Bond Stabilized and PPi Released (Homo sapiens)
Pol II Initiation complex with phosphodiester-PPi intermediate [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
pol II transcription complex [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP (Homo sapiens)
Pol II Initiation complex with phosphodiester-PPi intermediate [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Pol II initiation complex [nucleoplasm] (Homo sapiens)
RNA Polymearse II:NTP:TFIIF complex [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening (Homo sapiens)
Formation of the closed pre-initiation complex (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
pol II closed pre-initiation complex [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Metabolism of RNA (Homo sapiens)
mRNA Capping (Homo sapiens)
Activation of GT (Homo sapiens)
RNA Pol II with phosphorylated CTD: CE complex [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
RNA Pol II with phosphorylated CTD: CE complex with activated GT [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Capping complex formation (Homo sapiens)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Capping complex (initial) [nucleoplasm] (Homo sapiens)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Dissociation of transcript with 5'-GMP from GT (Homo sapiens)
Capping complex (GpppN..) [nucleoplasm] (Homo sapiens)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Capping complex (with freed 5'- GMP) [nucleoplasm] (Homo sapiens)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Formation of the CE:GMP intermediate complex (Homo sapiens)
Capping complex (intermediate) [nucleoplasm] (Homo sapiens)
Covalent CE:GMP intermediate complex [nucleoplasm] (Homo sapiens)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Capping complex (hydrolyzed) [nucleoplasm] (Homo sapiens)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme (Homo sapiens)
Capping complex (hydrolyzed) [nucleoplasm] (Homo sapiens)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Capping complex (initial) [nucleoplasm] (Homo sapiens)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Methylation of GMP-cap by RNA Methyltransferase (Homo sapiens)
Capping complex (with freed 5'- GMP) [nucleoplasm] (Homo sapiens)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
RNA Polymerase II CTD (phosphorylated) binds to CE (Homo sapiens)
Pol II transcription complex with (ser5) phosphorylated CTD containing extruded transcript to +30 [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
RNA Pol II with phosphorylated CTD: CE complex [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) (Homo sapiens)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
RNA Pol II with phosphorylated CTD: CE complex with activated GT [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA (Homo sapiens)
Capping complex (intermediate) [nucleoplasm] (Homo sapiens)
Covalent CE:GMP intermediate complex [nucleoplasm] (Homo sapiens)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
Capping complex (GpppN..) [nucleoplasm] (Homo sapiens)
CE:Pol II CTD:Spt5 complex [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
ERCC3 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:P19447 ERCC3
Gene Names
ERCC3, XPB, XPBC
Chain
chain:1-782
Reference Genes
BioGPS Gene:2071 ERCC3
COSMIC (genes):ERCC3 ERCC3
CTD Gene:2071 ERCC3
dbSNP Gene:2071 ERCC3
ENSEMBL:ENSG00000163161 ERCC3
HGNC:3435 ERCC3
KEGG:hsa:2071 ERCC3
Monarch:2071 ERCC3
NCBI Gene:2071 ERCC3
OMIM:133510 ERCC3
UCSC:P19447 ERCC3
Reference Transcript
RefSeq:NM_000122.1 ERCC3
Other Identifiers
11754646_a_at
11756348_a_at
16902448
1885_at
202176_PM_at
202176_at
2071
2388349
2574756
2574757
2574759
2574760
2574761
2574762
2574768
2574771
2574773
2574774
2574775
2574776
2574777
2574778
2574779
2574780
2574781
2574782
2574783
2574784
2574785
2574786
2574787
2574788
2574789
2574790
2574791
2574793
2574794
2574795
2574796
2574797
3285688
8054978
8054995
A_23_P5325
GE494975
GE57929
GO:0000112
GO:0000439
GO:0000717
GO:0001666
GO:0003677
GO:0003678
GO:0003684
GO:0003824
GO:0004386
GO:0005515
GO:0005524
GO:0005634
GO:0005654
GO:0005669
GO:0005675
GO:0006265
GO:0006281
GO:0006283
GO:0006289
GO:0006351
GO:0006366
GO:0006367
GO:0006368
GO:0006915
GO:0006979
GO:0008104
GO:0009411
GO:0009650
GO:0012501
GO:0016787
GO:0016853
GO:0016887
GO:0030154
GO:0032508
GO:0035315
GO:0043065
GO:0043138
GO:0043226
GO:0048568
GO:0048856
GO:0097550
GO:0140097
GO:0140640
GO:0140657
GO:1901990
GO:1990841
HMNXSV003027299
ILMN_1740216
M31899_at
PH_hs_0004500
TC02002278.hg
g4557562_3p_at
Participates
as a component of
TFIIH Core [nucleoplasm] (Homo sapiens)
TFIIH [nucleoplasm] (Homo sapiens)
Inferred To
xpb-1 [nucleoplasm]
(Caenorhabditis elegans)
ERCC3 [nucleoplasm]
(Bos taurus)
ERCC3 [nucleoplasm]
(Canis familiaris)
ERCC3 [nucleoplasm]
(Danio rerio)
ERCC3 [nucleoplasm]
(Dictyostelium discoideum)
ERCC3 [nucleoplasm]
(Drosophila melanogaster)
ERCC3 [nucleoplasm]
(Gallus gallus)
ERCC3 [nucleoplasm]
(Mus musculus)
ERCC3 [nucleoplasm]
(Plasmodium falciparum)
ERCC3 [nucleoplasm]
(Rattus norvegicus)
ERCC3 [nucleoplasm]
(Saccharomyces cerevisiae)
ERCC3 [nucleoplasm]
(Schizosaccharomyces pombe)
ERCC3 [nucleoplasm]
(Sus scrofa)
ercc3 [nucleoplasm]
(Xenopus tropicalis)
Cross References
RefSeq
NP_000113.1
OpenTargets
ENSG00000163161
ENSEMBL
ENSP00000285398
,
ENST00000285398
HPA
ENSG00000163161-ERCC3
PRO
P19447
Pharos - Targets
P19447
Orphanet
ERCC3
HMDB Protein
HMDBP11733
PDB
7AD8
,
8EBT
,
8EBS
,
8WAQ
,
8WAO
,
8WAN
,
8WAR
,
8BVW
,
7LBM
,
7NVZ
,
8GXS
,
7EGB
,
6NMI
,
7NVX
,
8GXQ
,
5IY9
,
8WAL
,
5IVW
,
7NVY
,
5IY8
,
8EBY
,
7NVW
,
7NVR
,
7EGC
,
5IY7
,
6O9M
,
8WAP
,
6O9L
,
4ERN
,
7NVV
,
8WAK
,
8WAS
,
6RO4
,
8EBV
,
5OF4
,
5IY6
,
7NW0
,
7ENC
,
8EBX
,
7ENA
,
8EBW
,
8EBU
,
8BYQ
Interactors (11)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P50613 CDK7
1
CDK7 [nucleoplasm]
(R-HSA-69218)
0.848
9
UniProt:P14373 TRIM27
2
TRIM27 [cytosol]
(R-HSA-8851002)
TRIM27 [nucleoplasm]
(R-HSA-2997690)
0.666
4
UniProt:P98170 XIAP
3
XIAP [cytosol]
(R-HSA-50849)
K48pUb-XIAP [cytosol]
(R-HSA-5675477)
XIAP [nucleoplasm]
(R-HSA-3322366)
0.666
4
UniProt:Q01831 XPC
5
monoSUMO1-K655-XPC [nucleoplasm]
(R-HSA-4570458)
Ub,SUMO,K63polyUb-XPC [nucleoplasm]
(R-HSA-6790522)
Ub,SUMO-XPC [nucleoplasm]
(R-HSA-6790460)
Ub-XPC [nucleoplasm]
(R-HSA-6782944)
XPC [nucleoplasm]
(R-HSA-67441)
0.59
3
UniProt:P62196
2
PSMC5 [nucleoplasm]
(R-MMU-174312)
PSMC5 [cytosol]
(R-MMU-68780)
0.581
6
UniProt:P62195 PSMC5
2
PSMC5 [cytosol]
(R-HSA-68780)
PSMC5 [nucleoplasm]
(R-HSA-174312)
0.576
4
UniProt:Q9Y5V3 MAGED1
1
MAGED1 [cytosol]
(R-HSA-196002)
0.556
3
UniProt:Q13573 SNW1
1
SNW1 [nucleoplasm]
(R-HSA-351663)
0.556
3
UniProt:P28715 ERCC5
1
ERCC5 [nucleoplasm]
(R-HSA-67447)
0.527
2
UniProt:Q93009 USP7
2
USP7 [nucleoplasm]
(R-HSA-3215278)
USP7 [cytosol]
(R-HSA-8853511)
0.527
2
UniProt:Q08J23 NSUN2
1
NSUN2 [nucleoplasm]
(R-HSA-6782382)
0.527
2
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