Reactome | USP13 [cytosol]

USP13 [cytosol]

Stable Identifier

R-HSA-6781893

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Ubiquitin carboxyl-terminal hydrolase 13 ecNumber3.4.19.12/ecNumber, UBP13_HUMAN

Locations in the PathwayBrowser for interactor UniProt:P54252 ATXN3

Expand all

External Reference Information

External Reference

UniProt:Q92995 USP13

Gene Names

USP13, ISOT3

Chain

chain:1-863

Reference Genes

BioGPS Gene:8975 USP13

COSMIC (genes):USP13 USP13

CTD Gene:8975 USP13

dbSNP Gene:8975 USP13

ENSEMBL:ENSG00000058056 USP13

ENSEMBL_homo_sapiens_GENE:ENSG00000058056.10 USP13

HGNC:12611 USP13

KEGG Gene (Homo sapiens):8975 USP13

Monarch:8975 USP13

NCBI Gene:8975 USP13

OMIM:603591 USP13

UCSC:Q92995 USP13

Reference Transcript

RefSeq:NM_003940.2 USP13

Other Identifiers

11722911_at

11722912_at

11722913_s_at

16948320

205356_PM_at

205356_at

226902_PM_at

226902_at

227788_PM_at

227788_at

2654092

2654093

2654094

2654099

2654103

2654108

2654112

2654113

2654114

2654116

2654117

2654118

2654121

2654122

2654128

2654129

2654130

2654131

2654136

2654137

2654139

2654141

2654142

2654146

2654148

2654149

2654152

2654154

2654155

2654156

2654157

2654158

2654159

2654160

40701_at

45855_at

49358_at

60531_at

8084100

83157_at

8975

A_14_P105739

A_23_P40989

GE52966

GE59397

GO:0003824

GO:0004197

GO:0004843

GO:0005515

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0006351

GO:0006355

GO:0006508

GO:0006914

GO:0008233

GO:0008234

GO:0008270

GO:0008283

GO:0010506

GO:0016579

GO:0016787

GO:0019538

GO:0030154

GO:0030163

GO:0030318

GO:0031625

GO:0035523

GO:0036211

GO:0036506

GO:0043130

GO:0043226

GO:0044313

GO:0044389

GO:0046872

GO:0050821

GO:0051087

GO:0070536

GO:0070628

GO:0140096

GO:1904288

GO:1904294

GO:1990380

HMNXSV003027059

Hs.20007.0.A1_3p_at

Hs.29074.0.A1_3p_at

PH_hs_0004824

PH_hs_0038811

TC03000957.hg

U75362_at

g4507848_3p_at

Participates

as a component of

as an input of

USP13 binds SIAH2 (Homo sapiens)

as a member of

USP13,OTUD3 [cytosol] (Homo sapiens)

Other forms of this molecule

USP13 [nucleoplasm]

Inferred To

USP13 [cytosol] (Bos taurus)

USP13 [cytosol] (Canis familiaris)

USP13 [cytosol] (Danio rerio)

USP13 [cytosol] (Drosophila melanogaster)

USP13 [cytosol] (Gallus gallus)

USP13 [cytosol] (Mus musculus)

USP13 [cytosol] (Rattus norvegicus)

USP13 [cytosol] (Schizosaccharomyces pombe)

USP13 [cytosol] (Sus scrofa)

ubpA [cytosol] (Dictyostelium discoideum)

Cross References

RefSeq

NP_003931.2

OpenTargets

ENSG00000058056

ZINC - Substances

UBP13_HUMAN

ZINC target

Q92995

PRO

Q92995

PDB

2L80, 2LBC

IntEnz

3.4.19.12

HPA

ENSG00000058056-USP13

GeneCards

Q92995

Ensembl

ENSG00000058056, ENSP00000263966, ENST00000263966, ENSP00000417146, ENST00000496897

Pharos - Targets

Q92995

ZINC - Predictions - Purchasable

UBP13_HUMAN

HMDB Protein

HMDBP10132

Interactors (11)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P0DTD1-PRO_0000449630 REP			0.669	4
UniProt:Q14683 SMC1A	4	SMC1A [cytosol] (R-HSA-2484798) SMC1A [chromosome] (R-HSA-1638774) SMC1A [chromosome, centromeric region] (R-HSA-2466015) SMC1A [nucleoplasm] (R-HSA-64561)	0.643	3
UniProt:Q15038 DAZP2			0.556	3
UniProt:P54252 ATXN3	2	ATXN3 [nucleoplasm] (R-HSA-6783285) ATXN3 [cytosol] (R-HSA-5625607)	0.556	3
UniProt:Q13148 TADBP			0.556	3
UniProt:Q9UQE7 SMC3	6	SMC3 [cytosol] (R-HSA-2545223) 2xAcK-SMC3 [cytosol] (R-HSA-2484792) 2xAcK-SMC3 [chromosome] (R-HSA-2468146) 2xAcK-SMC3 [chromosome, centromeric region] (R-HSA-2468148) 2xAcK-SMC3 [nucleoplasm] (R-HSA-2468050) SMC3 [nucleoplasm] (R-HSA-163009)	0.527	2
UniProt:Q9BUL9 RPP25	1	RPP25 [nucleoplasm] (R-HSA-5696782)	0.527	2
UniProt:Q8NBX0 SCCPDH	2	SCCPDH [extracellular region] (R-HSA-8862997) SCCPDH [platelet alpha granule lumen] (R-HSA-8862982)	0.527	3
UniProt:O60216 RAD21	14	monoSUMO1-K-RAD21 [nucleoplasm] (R-HSA-3108183) p-S454-RAD21 [cytosol] (R-HSA-2500310) p-S454-RAD21 [chromosome] (R-HSA-2485164) RAD21 [cytosol] (R-HSA-2484795) p-S454-RAD21(451-631) [cytosol] (R-HSA-2500309) RAD21(173-450) [cytosol] (R-HSA-2500308) RAD21(1-172) [cytosol] (R-HSA-2484901) RAD21(173-450) [chromosome, centromeric region] (R-HSA-2500296) p-S454-RAD21(451-631) [chromosome, centromeric region] (R-HSA-2467790) RAD21(1-172) [chromosome, centromeric region] (R-HSA-2467793) p-S454-RAD21 [chromosome, centromeric region] (R-HSA-2485163) RAD21 [chromosome] (R-HSA-1638775) RAD21 [nucleoplasm] (R-HSA-163042) RAD21 [chromosome, centromeric region] (R-HSA-2466012)	0.527	2
UniProt:Q9BYV6 TRI55			0.508	2
UniProt:Q969Q1 TRIM63	1	TRIM63 [cytosol] (R-HSA-976020)	0.508	2

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