Reactome | ISY1 [nucleoplasm]

ISY1 [nucleoplasm]

Stable Identifier

R-HSA-6781963

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Pre-mRNA-splicing factor ISY1 homolog, KIAA1160

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9ULR0 ISY1

Gene Names

ISY1, KIAA1160

Chain

chain:1-285

Reference Genes

COSMIC (genes):ISY1 Q9ULR01

dbSNP Gene:100534599 Q9ULR01

dbSNP Gene:57461 Q9ULR01

ENSEMBL:ENSG00000240682 ISY1

Participates

as a component of

Inferred To

Ghost homologue of ISY1 [nucleoplasm] (Xenopus tropicalis)

LOC102162880 [nucleoplasm] (Sus scrofa)

ISY1 [nucleoplasm] (Bos taurus)

ISY1 [nucleoplasm] (Canis familiaris)

ISY1 [nucleoplasm] (Gallus gallus)

ISY1 [nucleoplasm] (Plasmodium falciparum)

ISY1 [nucleoplasm] (Saccharomyces cerevisiae)

cwf12 [nucleoplasm] (Schizosaccharomyces pombe)

Isy1 [nucleoplasm] (Mus musculus)

Isy1 [nucleoplasm] (Rattus norvegicus)

isy-1 [nucleoplasm] (Caenorhabditis elegans)

Dmel\CG9667 [nucleoplasm] (Drosophila melanogaster)

isy1 [nucleoplasm] (Danio rerio)

isy1 [nucleoplasm] (Dictyostelium discoideum)

Interactors (9)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q14562 DHX8	1	DHX8 [nucleoplasm] (R-HSA-5688092)	0.632	4
UniProt:P09661 SNRPA1	1	SNRPA1 [nucleoplasm] (R-HSA-71958)	0.59	4
UniProt:Q9CSN1 Snw1	1	Snw1 [nucleoplasm] (R-MMU-2065315)	0.564	2
UniProt:Q8IYI6 EXOC8	2	EXOC8 [plasma membrane] (R-HSA-264948) EXOC8 [cytosol] (R-HSA-5623388)	0.556	3
UniProt:P40692 MLH1	3	MLH1 [nucleoplasm] (R-HSA-912495) MLH1 H329P [nucleoplasm] (R-HSA-5444512) MLH1 S252* [nucleoplasm] (R-HSA-5444526)	0.556	3
UniProt:P36957 DLST	5	Lipo-K110-DLST [mitochondrial matrix] (R-HSA-69993) SuccinyllipoH2-K110-DLST [mitochondrial matrix] (R-HSA-9853502) LipoH2-K110-DLST [mitochondrial matrix] (R-HSA-9853485) DLST [mitochondrial matrix] (R-HSA-6792574) GlutaryllipoH2-K110-DLST [mitochondrial matrix] (R-HSA-9858581)	0.556	3
UniProt:P27797 CALR	6	CALR [lumenal side of endoplasmic reticulum membrane] (R-HSA-985502) CALR [endoplasmic reticulum lumen] (R-HSA-195905) CALR [extracellular region] (R-HSA-2197641) CALR [endocytic vesicle lumen] (R-HSA-2239448) CALR [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-8863866) CALR [phagocytic vesicle membrane] (R-HSA-1236879)	0.556	3
UniProt:P37173 TGFBR2	9	TGFBR2 [plasma membrane] (R-HSA-170842) NEDD8-K556,K567-TGFBR2 [plasma membrane] (R-HSA-4332222) TGFBR2 K128Sfs35 [cytosol] (R-HSA-3642166) TGFBR2 K128Afs3 [cytosol] (R-HSA-3642173) TGFBR2 R528C [plasma membrane] (R-HSA-3640899) TGFBR2 R528H [plasma membrane] (R-HSA-3640894) TGFBR2 D522N [plasma membrane] (R-HSA-3640907) TGFBR2 E526Q [plasma membrane] (R-HSA-3645770) TGFBR2 Y470D [plasma membrane] (R-HSA-3640905)	0.556	3
UniProt:P24863 CCNC	1	CCNC [nucleoplasm] (R-HSA-212418)	0.556	3