Reactome | TYW3 [cytoplasm]

TYW3 [cytoplasm]

Stable Identifier

R-HSA-6782888

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytoplasm

Synonyms

tRNA wybutosine-synthesizing protein 3 homolog, TYW3_HUMAN

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Locations in the PathwayBrowser for interactor UniProt:Q9C0B1 FTO

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External Reference Information

External Reference

UniProt:Q6IPR3 TYW3

Gene Names

TYW3, C1orf171

Chain

chain:1-259

Reference Genes

BioGPS Gene:127253 TYW3

COSMIC (genes):TYW3 TYW3

CTD Gene:127253 TYW3

dbSNP Gene:127253 TYW3

ENSEMBL:ENSG00000162623 TYW3

ENSEMBL_homo_sapiens_GENE:ENSG00000162623.16 TYW3

HGNC:24757 TYW3

KEGG Gene (Homo sapiens):127253 TYW3

Monarch:127253 TYW3

NCBI Gene:127253 TYW3

OMIM:611245 TYW3

UCSC:Q6IPR3 TYW3

Reference Transcript

Other Identifiers

11739265_at

11751727_s_at

127253

16666204

227141_PM_at

227141_at

2342392

2342393

2342396

2342397

2342399

2342402

2342405

2342406

2342408

2342409

2342412

2342415

2342417

2342418

2342419

2342420

2342421

2342422

57714_at

62967_r_at

7902345

A_14_P110762

A_23_P103172

A_23_P103180

A_24_P396327

GE552954

GO:0003824

GO:0005515

GO:0005737

GO:0006399

GO:0006400

GO:0008033

GO:0008168

GO:0008175

GO:0016740

GO:0030488

GO:0031591

GO:0032259

GO:0140098

GO:1901135

HMNXSV003033785

HMNXSV003055430

Hs.283713.1.A1_3p_s_at

ILMN_1726842

PH_hs_0016785

PH_hs_0035811

TC01000772.hg

TC01004481.hg

Cross References

RefSeq

NP_001156388.1, XP_006710410.1, NP_612476.1

OpenTargets

ENSG00000162623

GeneCards

Q6IPR3

HPA

ENSG00000162623-TYW3

Ensembl

ENST00000457880, ENSP00000359904, ENSG00000162623, ENST00000370867, ENSP00000407025

PRO

Q6IPR3

Pharos - Targets

Q6IPR3

HMDB Protein

HMDBP09051

Interactors (13)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q96D03 DDT4L			0.556	3
UniProt:Q9NRD5 PICK1	2	PICK1 [endocytic vesicle membrane] (R-HSA-417017) PICK1 [plasma membrane] (R-HSA-416989)	0.556	3
UniProt:Q92673 SORL1	2	SORL1 [endosome membrane] (R-HSA-8871475) SORL1 [Golgi membrane] (R-HSA-8871510)	0.527	3
UniProt:O75096 LRP4	1	LRP4 [plasma membrane] (R-HSA-2467621)	0.527	2
UniProt:Q99435 NELL2	1	NELL2 [extracellular region] (R-HSA-9010198)	0.527	2
UniProt:Q9BRR0 ZKSCAN3	1	ZKSCAN3 [nucleoplasm] (R-HSA-1027422)	0.527	2
UniProt:Q96JK2 DCAF5	1	DCAF5 [nucleoplasm] (R-HSA-8955189)	0.527	2
UniProt:P09382 LGALS1	2	p-LGALS1 [endoplasmic reticulum lumen] (R-HSA-8957003) LGALS1 [endoplasmic reticulum lumen] (R-HSA-8956711)	0.527	2
UniProt:Q9C0B1 FTO	1	FTO [nucleoplasm] (R-HSA-8857715)	0.527	2
UniProt:P01130 LDLR	4	LDLR [endolysosome membrane] (R-HSA-6784818) LDLR [endosome membrane] (R-HSA-171127) LDLR [clathrin-coated endocytic vesicle membrane] (R-HSA-171105) LDLR [plasma membrane] (R-HSA-171053)	0.527	2
UniProt:Q969J2 ZKSCAN4	1	ZKSCAN4 [nucleoplasm] (R-HSA-1027423)	0.527	2
UniProt:Q9Y496 KIF3A	3	KIF3A [cilium] (R-HSA-5610394) KIF3A [cytosol] (R-HSA-984767) KIF3A [ciliary tip] (R-HSA-5625377)	0.527	3
UniProt:P48506 GCLC	4	GCLC H370L [cytosol] (R-HSA-5602842) GCLC P185L [cytosol] (R-HSA-5602975) GCLC R127C [cytosol] (R-HSA-5602822) GCLC [cytosol] (R-HSA-174385)	0.527	3

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